(Q35853655)

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Differential effect of long-term leucine supplementation on skeletal muscle and adipose tissue in old rats: an insulin signaling pathway approach.

scientific article published on 7 April 2011

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21472380%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Differential effect of long-term leucine supplementation on skeletal muscle and adipose tissue in old rats: an insulin signaling pathway approach (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21472380%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Gilbert Zeanandin

1

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27 January 2020

Stéphane M. Schneider

3

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27 January 2020

Isabelle Mothe-Satney

6

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27 January 2020

Dominique Dardevet

7

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27 January 2020

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Michèle Balage

2

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27 January 2020

Joëlle Dupont

4

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27 January 2020

Xavier Hébuterne

5

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Europe PubMed Central

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27 January 2020

publication date

7 April 2011

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Europe PubMed Central

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27 January 2020

1 reference

Europe PubMed Central

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27 January 2020

34

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27 January 2020

2

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27 January 2020

371-387

1 reference

Europe PubMed Central

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27 January 2020

Long-term effects of leucine supplementation on body composition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

11 July 2018

Time-resolved and tissue-specific systems analysis of the pathogenesis of insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

11 July 2018

Leucine deprivation decreases fat mass by stimulation of lipolysis in white adipose tissue and upregulation of uncoupling protein 1 (UCP1) in brown adipose tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

11 July 2018

Dietary implications on mechanisms of sarcopenia: roles of protein, amino acids and antioxidants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

11 July 2018

Physiopathological mechanism of sarcopenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

11 July 2018

A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

11 July 2018

Long-term leucine supplementation does not increase muscle mass or strength in healthy elderly men.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

11 July 2018

Leucine for retention of lean mass on a hypocaloric diet

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

11 July 2018

Antioxidant supplementation restores defective leucine stimulation of protein synthesis in skeletal muscle from old rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

11 July 2018

Phosphorylation of IRS proteins, insulin action, and insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

11 July 2018

The secretory function of adipocytes in the physiology of white adipose tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

11 July 2018

Disruption of BCATm in mice leads to increased energy expenditure associated with the activation of a futile protein turnover cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

11 July 2018

Identification of IRS-1 Ser-1101 as a target of S6K1 in nutrient- and obesity-induced insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

11 July 2018

Role of dietary proteins and amino acids in the pathogenesis of insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

11 July 2018

Nutrient signaling components controlling protein synthesis in striated muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

11 July 2018

The two TORCs and Akt.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

11 July 2018

Increased availability of leucine with leucine-rich whey proteins improves postprandial muscle protein synthesis in aging rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

11 July 2018

Leucine supplementation improves muscle protein synthesis in elderly men independently of hyperaminoacidaemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

11 July 2018

Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

11 July 2018

Hypothalamic mTOR signaling regulates food intake

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

11 July 2018

Potential importance of leucine in treatment of obesity and the metabolic syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

11 July 2018

Branched-chain amino acids: the best compromise to achieve anabolism?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

11 July 2018

Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

11 July 2018

regulation of peroxisome proliferator-activated receptor-gamma activity by mammalian target of rapamycin and amino acids in adipogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

11 July 2018

The role of leucine in weight loss diets and glucose homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

11 July 2018

Amino acid and insulin signaling via the mTOR/p70 S6 kinase pathway. A negative feedback mechanism leading to insulin resistance in skeletal muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

11 July 2018

Leptin secretion from adipose tissue in women. Relationship to plasma levels and gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

11 July 2018

Metabolic fate of leucine: a significant sterol precursor in adipose tissue and muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

11 July 2018

Oxidation of leucine by rat skeletal muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

11 July 2018

Insulin resistance of obese Zucker rats exercise trained at two different intensities.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

11 July 2018

Leucine supplementation in rats induced a delay in muscle IR/PI3K signaling pathway associated with overall impaired glucose tolerance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

24 September 2018

Presence of low-grade inflammation impaired postprandial stimulation of muscle protein synthesis in old rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

24 September 2018

Hypoglycemic effect of isoleucine involves increased muscle glucose uptake and whole body glucose oxidation and decreased hepatic gluconeogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

24 September 2018

A high proportion of leucine is required for optimal stimulation of the rate of muscle protein synthesis by essential amino acids in the elderly.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

24 September 2018

A leucine-supplemented diet restores the defective postprandial inhibition of proteasome-dependent proteolysis in aged rat skeletal muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

24 September 2018

Isoleucine, a blood glucose-lowering amino acid, increases glucose uptake in rat skeletal muscle in the absence of increases in AMP-activated protein kinase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

24 September 2018

Branched-chain amino acids improve glucose metabolism in rats with liver cirrhosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

24 September 2018

Differential effects of insulin and dietary amino acids on muscle protein synthesis in adult and old rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

24 September 2018

Chronic leptin treatment enhances insulin-stimulated glucose disposal in skeletal muscle of high-fat fed rodents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

24 September 2018

Isoleucine, a potent plasma glucose-lowering amino acid, stimulates glucose uptake in C2C12 myotubes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

24 September 2018

Leucine promotes glucose uptake in skeletal muscles of rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

24 September 2018

Tissue-specific effects of chronic dietary leucine and norleucine supplementation on protein synthesis in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

24 September 2018

Leucine is a direct-acting nutrient signal that regulates protein synthesis in adipose tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

24 September 2018

Influence of protein and amino acids on food intake in the rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312629

24 September 2018

Insulin-like growth factor-1 and insulin resistance in skeletal muscles of adult and old rats

1 reference

https://api.crossref.org/works/10.1007%2FS11357-011-9246-0

21 January 2018

Postprandial stimulation of muscle protein synthesis in old rats can be restored by a leucine-supplemented meal

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472380

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Co-ingestion of a protein hydrolysate with or without additional leucine effectively reduces postprandial blood glucose excursions in Type 2 diabetic men

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472380

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increasing dietary leucine intake reduces diet-induced obesity and improves glucose and cholesterol metabolism in mice via multimechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472380

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leucine-supplemented meal feeding for ten days beneficially affects postprandial muscle protein synthesis in old rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472380

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L-Leucine activates branched chain alpha-keto acid dehydrogenase in rat adipose tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472380

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472380

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factor-1 and insulin resistance in skeletal muscles of adult and old rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472380

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered response of protein synthesis to nutritional state and endurance training in old rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472380

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Co-ingestion of a protein hydrolysate and amino acid mixture with carbohydrate improves plasma glucose disposal in patients with type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472380

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of in vitro rat muscle protein synthesis by leucine decreases with age

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472380

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aging is associated with diminished accretion of muscle proteins after the ingestion of a small bolus of essential amino acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472380

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11357-011-9246-0

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21472380%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21472380%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21472380%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

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