(Q35855469)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15292914%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

review article

1 reference

title

Gene therapy progress and prospects. Downregulating gene expression: the impact of RNA interference (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15292914%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

0 references

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15292914%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

author name string

Caplen NJ

series ordinal

1

1 reference

10 August 2017

1 August 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15292914%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15292914%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

volume

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15292914%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

issue

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15292914%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

page(s)

1241-1248

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15292914%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/sj.gt.3302324

31 December 2019

exact match

0 references

cites work

Argonaute2, a link between genetic and biochemical analyses of RNAi

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Single-stranded antisense siRNAs guide target RNA cleavage in RNAi

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

A microRNA in a multiple-turnover RNAi enzyme complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Short-interfering-RNA-mediated gene silencing in mammalian cells requires Dicer and eIF2C translation initiation factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Asymmetry in the assembly of the RNAi enzyme complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Functional siRNAs and miRNAs Exhibit Strand Bias

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Role for a bidentate ribonuclease in the initiation step of RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

RNA interference is mediated by 21- and 22-nucleotide RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Evidence that processed small dsRNAs may mediate sequence-specific mRNA degradation during RNAi in Drosophila embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

R2D2, a Bridge Between the Initiation and Effector Steps of the Drosophila RNAi Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

A micrococcal nuclease homologue in RNAi effector complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Specific interference with gene expression induced by long, double-stranded RNA in mouse embryonal teratocarcinoma cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

On the role of RNA amplification in dsRNA-triggered gene silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Systemic RNAi in C. elegans requires the putative transmembrane protein SID-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Transport of dsRNA into cells by the transmembrane protein SID-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

RNA interference is required for normal centromere function in fission yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Small RNAs correspond to centromere heterochromatic repeats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Establishment and maintenance of a heterochromatin domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

RNA interference machinery regulates chromosome dynamics during mitosis and meiosis in fission yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

RNAi-mediated targeting of heterochromatin by the RITS complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Distinct mechanisms determine transposon inheritance and methylation via small interfering RNA and histone modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Hairpin RNAs and retrotransposon LTRs effect RNAi and chromatin-based gene silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Dicer is essential for mouse development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

siRNAs can function as miRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

A system for stable expression of short interfering RNAs in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Stable suppression of gene expression by RNAi in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Stable suppression of tumorigenicity by virus-mediated RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Identification of Modulators of TRAIL-Induced Apoptosis via RNAi-Based Phenotypic Screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Systematic functional analysis of the Caenorhabditis elegans genome using RNAi

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Identification of Hedgehog pathway components by RNAi in Drosophila cultured cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

A functional genomic analysis of cell morphology using RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

A resource for large-scale RNA-interference-based screens in mammals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

A large-scale RNAi screen in human cells identifies new components of the p53 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

RNAi microarray analysis in cultured mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

High-throughput selection of effective RNAi probes for gene silencing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Small interfering RNA and gene silencing in transgenic mice and rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Germline transmission of RNAi in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Transgenic RNA interference in ES cell-derived embryos recapitulates a genetic null phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Local gene knockdown in the brain using viral-mediated RNA interference.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Tissue-specific RNA interference in postimplantation mouse embryos with endoribonuclease-prepared short interfering RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

siRNAs generated by recombinant human Dicer induce specific and significant but target site-independent gene silencing in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Restriction enzyme-generated siRNA (REGS) vectors and libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Enzymatic production of RNAi libraries from cDNAs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Rational siRNA design for RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents. A comparative analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

RNA interference may be more potent than antisense RNA in human cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Comparison of the Suppressive Effects of Antisense Oligonucleotides and siRNAs Directed Against the Same Targets in Mammalian Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Independent combinatorial effect of antisense oligonucleotides and RNAi-mediated specific inhibition of the recombinant rat P2X3 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Activation of the interferon system by short-interfering RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Expression profiling reveals off-target gene regulation by RNAi

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Allele-specific silencing of dominant disease genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

siRNA-mediated gene silencing in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Cloned zebrafish by nuclear transfer from long-term-cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

RNA interference in adult mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Caspase 8 small interfering RNA prevents acute liver failure in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Fas siRNA reduces apoptotic cell death of allogeneic-transplanted hepatocytes in mouse spleen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Induction of an interferon response by RNAi vectors in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

Transposon silencing in the Caenorhabditis elegans germ line by natural RNAi

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

7 January 2021

Recombinant Dicer efficiently converts large dsRNAs into siRNAs suitable for gene silencing

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

1 reference

7 January 2021

Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

7 January 2021

Efficient delivery of siRNA for inhibition of gene expression in postnatal mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

7 January 2021

RNA interference targeting Fas protects mice from fulminant hepatitis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302324

7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3302324

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15292914%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference