(Q35856748)

English

A single-nucleotide polymorphism in a half-binding site creates p53 and estrogen receptor control of vascular endothelial growth factor receptor 1.

scientific article published on 22 January 2007

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scholarly article

1 reference

Europe PubMed Central

10 August 2017

A single-nucleotide polymorphism in a half-binding site creates p53 and estrogen receptor control of vascular endothelial growth factor receptor 1. (English)

1 reference

Europe PubMed Central

10 August 2017

0 references

single-nucleotide polymorphism

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Gilbert Schönfelder

object named as

Gilbert Schönfelder

5

0 references

author name string

Daniel Menendez

1

1 reference

Europe PubMed Central

10 August 2017

Alberto Inga

2

1 reference

Europe PubMed Central

10 August 2017

Joyce Snipe

3

1 reference

Europe PubMed Central

10 August 2017

Oliver Krysiak

4

1 reference

Europe PubMed Central

10 August 2017

Michael A Resnick

6

1 reference

Europe PubMed Central

10 August 2017

language of work or name

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publication date

22 January 2007

1 reference

Europe PubMed Central

10 August 2017

Molecular and Cellular Biology

1 reference

Europe PubMed Central

10 August 2017

27

1 reference

Europe PubMed Central

10 August 2017

2590-2600

1 reference

Europe PubMed Central

10 August 2017

7

1 reference

Europe PubMed Central

10 August 2017

Transcriptional regulation by p53: one protein, many possibilities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

Estrogen receptor-alpha binds p53 tumor suppressor protein directly and represses its function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

A SNP in the flt-1 promoter integrates the VEGF system into the p53 transcriptional network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

A global map of p53 transcription-factor binding sites in the human genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

Genome-wide prediction of mammalian enhancers based on analysis of transcription-factor binding affinity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

Signal transduction by VEGF receptors in regulation of angiogenesis and lymphangiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

VEGF as a key mediator of angiogenesis in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

Chromatin immunoprecipitation-based screen to identify functional genomic binding sites for sequence-specific transactivators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

MED1/TRAP220 exists predominantly in a TRAP/ Mediator subpopulation enriched in RNA polymerase II and is required for ER-mediated transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

MatInspector and beyond: promoter analysis based on transcription factor binding sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

Functionally distinct polymorphic sequences in the human genome that are targets for p53 transactivation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

Association between intratumoral free and total VEGF, soluble VEGFR-1, VEGFR-2 and prognosis in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

Transduction of soluble Flt-1 gene to peritoneal mesothelial cells can effectively suppress peritoneal metastasis of gastric cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

Anatomy of the estrogen response element

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

Genomic targets of nuclear estrogen receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

Unbiased mapping of transcription factor binding sites along human chromosomes 21 and 22 points to widespread regulation of noncoding RNAs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

Functional mutants of the sequence-specific transcription factor p53 and implications for master genes of diversity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

The biology of VEGF and its receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

TRANSFAC: transcriptional regulation, from patterns to profiles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

Modulation of human NK cell lines by vascular endothelial growth factor and receptor VEGFR-1 (FLT-1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

Differential transactivation by the p53 transcription factor is highly dependent on p53 level and promoter target sequence.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

The TRAP/Mediator coactivator complex interacts directly with estrogen receptors alpha and beta through the TRAP220 subunit and directly enhances estrogen receptor function in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

Estrogen receptor interaction with estrogen response elements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

Surfing the p53 network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

Transcriptional regulation through Mediator-like coactivators in yeast and metazoan cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

The p53 pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

Inhibition of tumor growth by targeting tumor endothelium using a soluble vascular endothelial growth factor receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

Biological and clinical importance of the p53 tumor suppressor gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

Modulation of the transcriptional activity of thyroid hormone receptors by the tumor suppressor p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

p53 tagged sites from human genomic DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

A 13 bp palindrome is a functional estrogen responsive element and interacts specifically with estrogen receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

Definition of a consensus binding site for p53

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

11 July 2018

Soluble vascular endothelial growth factor receptor-1 (sFLT-1) mediates downregulation of FLT-1 and prevents activated neutrophils from women with preeclampsia from additional migration by VEGF.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

24 September 2018

Investigating single nucleotide polymorphism (SNP) density in the human genome and its implications for molecular evolution.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

24 September 2018

Vascular endothelial growth factor receptor Flt-1 negatively regulates developmental blood vessel formation by modulating endothelial cell division.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

24 September 2018

Vascular endothelial growth factor (VEGF) is an autocrine growth factor for VEGF receptor-positive human tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

24 September 2018

Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

24 September 2018

De novo expression of vascular endothelial growth factor in human pancreatic cancer: evidence for an autocrine mitogenic loop.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

24 September 2018

Expression of the VEGF-receptor Flt-1 in benign, premalignant and malignant prostate tissues.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

24 September 2018

Transcriptional activation of transforming growth factor alpha by estradiol: requirement for both a GC-rich site and an estrogen response element half-site.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

24 September 2018

Differential binding characteristics and cellular inhibition by soluble VEGF receptors 1 and 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899907

24 September 2018

Sequence Requirements for Estrogen Receptor Binding to Estrogen Response Elements

1 reference

https://pubmed.ncbi.nlm.nih.gov/17242190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53 inhibits hypoxia-inducible factor-stimulated transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/17242190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a natural soluble form of the vascular endothelial growth factor receptor, FLT-1, and its heterodimerization with KDR

1 reference

https://pubmed.ncbi.nlm.nih.gov/17242190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and function of vascular endothelial growth factor receptor-1 on human colorectal cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17242190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wild-type p53 suppresses angiogenesis in human leiomyosarcoma and synovial sarcoma by transcriptional suppression of vascular endothelial growth factor expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/17242190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen receptor protects p53 from deactivation by human double minute-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/17242190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cooperative binding of estrogen receptor to DNA depends on spacing of binding sites, flanking sequence, and ligand

1 reference

https://pubmed.ncbi.nlm.nih.gov/17242190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergism of closely adjacent estrogen-responsive elements increases their regulatory potential

1 reference

https://pubmed.ncbi.nlm.nih.gov/17242190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53 down-regulates ER-responsive genes by interfering with the binding of ER to ERE

1 reference

https://pubmed.ncbi.nlm.nih.gov/17242190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble VEGF receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17242190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The tumor suppressor p53 is a negative regulator of estrogen receptor signaling pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/17242190

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.01742-06

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

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