(Q35857300)

English

Simvastatin Attenuates Oxidative Stress, NF-κB Activation, and Artery Calcification in LDLR-/- Mice Fed with High Fat Diet via Down-regulation of Tumor Necrosis Factor-α and TNF Receptor 1

scientific article published in December 2015

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Simvastatin Attenuates Oxidative Stress, NF-κB Activation, and Artery Calcification in LDLR-/- Mice Fed with High Fat Diet via Down-regulation of Tumor Necrosis Factor-α and TNF Receptor 1 (English)

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

0 references

1 reference

based on heuristic

inferred from title

author name string

Chih-Pei Lin

1

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Po-Hsun Huang

2

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Chung Fang Lai

3

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Jaw-Wen Chen

4

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Shing-Jong Lin

5

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Jia-Shiong Chen

6

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

language of work or name

0 references

publication date

1 December 2015

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

10

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

12

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

e0143686

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

copyright license

Creative Commons Attribution 4.0 International

1 December 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

describes a project that uses

object named as

ImageQuant

2 references

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4666466/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

Effect of Simvastatin on Arterial Stiffness in Patients with Statin Myalgia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

Mechanisms and clinical consequences of vascular calcification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

Smooth muscle cell-specific runx2 deficiency inhibits vascular calcification.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

TNFR1-activated reactive oxidative species signals up-regulate osteogenic Msx2 programs in aortic myofibroblasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

Reactive oxygen species and inhibitors of inflammatory enzymes, NADPH oxidase, and iNOS in experimental models of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

Predictors of new-onset diabetes in patients treated with atorvastatin: results from 3 large randomized clinical trials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

α-Lipoic acid attenuates vascular calcification via reversal of mitochondrial function and restoration of Gas6/Axl/Akt survival pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

Endothelial ICAM-1 protein induction is regulated by cytosolic phospholipase A2α via both NF-κB and CREB transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

Blood pressure and vascular calcification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

Dysregulation of antioxidant mechanisms contributes to increased oxidative stress in calcific aortic valvular stenosis in humans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

Vascular calcification: pathobiology of a multifaceted disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

Msx2 exerts bone anabolism via canonical Wnt signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

Oxidative stress induces vascular calcification through modulation of the osteogenic transcription factor Runx2 by AKT signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

Simvastatin antagonizes tumor necrosis factor-alpha inhibition of bone morphogenetic proteins-2-induced osteoblast differentiation by regulating Smad signaling and Ras/Rho-mitogen-activated protein kinase pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

NADPH oxidases, reactive oxygen species, and hypertension: clinical implications and therapeutic possibilities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

Mechanisms of vascular calcification in chronic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

Vascular Bmp Msx2 Wnt signaling and oxidative stress in arterial calcification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

TNF-alpha represses transcription of human Bone Morphogenetic Protein-4 in lung epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

Medial vascular calcification in diabetes mellitus and chronic kidney disease: the role of inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

Rosuvastatin affecting aortic valve endothelium to slow the progression of aortic stenosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

Vascular calcification: pathobiological mechanisms and clinical implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

Vascular smooth muscle cell phenotypic plasticity and the regulation of vascular calcification.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

Bone morphogenetic protein-2 induces proinflammatory endothelial phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

Bone morphogenetic proteins in vascular calcification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

A randomized trial of intensive lipid-lowering therapy in calcific aortic stenosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

Regulation of bone morphogenetic protein-2 expression in endothelial cells: role of nuclear factor-kappaB activation by tumor necrosis factor-alpha, H2O2, and high intravascular pressure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

Msx2 promotes cardiovascular calcification by activating paracrine Wnt signals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

Vascular NADPH oxidases: molecular mechanisms of activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

Statins but not angiotensin-converting enzyme inhibitors delay progression of aortic stenosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

Beneficial cardiovascular pleiotropic effects of statins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

Vascular smooth muscle cells and calcification in atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

Signal transduction by tumor necrosis factor and its relatives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

Structural mechanism for statin inhibition of HMG-CoA reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

Arsenite stimulates plasma membrane NADPH oxidase in vascular endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

Non-lipid-related effects of statins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

Msx2 deficiency in mice causes pleiotropic defects in bone growth and ectodermal organ formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

Medial artery calcification. A neglected harbinger of cardiovascular complications in non-insulin-dependent diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

11 July 2018

The effect of statin therapy on arterial stiffness by measuring pulse wave velocity: a systematic review.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

24 September 2018

Tumor necrosis factor-alpha increases alkaline phosphatase expression in vascular smooth muscle cells via MSX2 induction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

24 September 2018

TNFalpha promotes osteogenic differentiation of human mesenchymal stem cells by triggering the NF-kappaB signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

24 September 2018

Annexin-mediated matrix vesicle calcification in vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

24 September 2018

Oxidant generation predominates around calcifying foci and enhances progression of aortic valve calcification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

24 September 2018

Aortic Msx2-Wnt calcification cascade is regulated by TNF-alpha-dependent signals in diabetic Ldlr-/- mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

24 September 2018

Effect of intensive versus standard lipid-lowering treatment with atorvastatin on the progression of calcified coronary atherosclerosis over 12 months: a multicenter, randomized, double-blind trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

24 September 2018

Elevated extracellular calcium levels induce smooth muscle cell matrix mineralization in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

24 September 2018

Simvastatin promotes atherosclerotic plaque stability in apoE-deficient mice independently of lipid lowering

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

24 September 2018

Phosphorus and uremic serum up-regulate osteopontin expression in vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

24 September 2018

Statins reduce inflammation in atheroma of nonhuman primates independent of effects on serum cholesterol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

24 September 2018

PKCzeta regulates TNF-alpha-induced activation of NADPH oxidase in endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

24 September 2018

Monocyte/macrophage regulation of vascular calcification in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4666466

24 September 2018

Coronary Artery Calcification in Older Adults to Age 99

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0143686

21 January 2018

HMG CoA reductase inhibitor (statin) and aortic valve calcium

1 reference

https://pubmed.ncbi.nlm.nih.gov/26625143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress and inflammation are differentially affected by atorvastatin, pravastatin, rosuvastatin, and simvastatin on lungs from mice exposed to cigarette smoke

1 reference

https://pubmed.ncbi.nlm.nih.gov/26625143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Statins protect human aortic smooth muscle cells from inorganic phosphate-induced calcification by restoring Gas6-Axl survival pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/26625143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pravastatin has cholesterol-lowering independent effects on the artery wall of atherosclerotic monkeys

1 reference

https://pubmed.ncbi.nlm.nih.gov/26625143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The antioxidant tempol ameliorates arterial medial calcification in uremic rats: important role of oxidative stress in the pathogenesis of vascular calcification in chronic kidney disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/26625143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular immunostaining of angiotensin-converting enzyme in human coronary atherosclerotic plaques

1 reference

https://pubmed.ncbi.nlm.nih.gov/26625143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis regulates human vascular calcification in vitro: evidence for initiation of vascular calcification by apoptotic bodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/26625143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of proinflammatory cytokine production by pravastatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/26625143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral vascular disease: who gets it and why? A histomorphological analysis of 261 arterial segments from 58 cases

1 reference

https://pubmed.ncbi.nlm.nih.gov/26625143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Arterial media calcification in patients with type 2 diabetes mellitus]

1 reference

https://pubmed.ncbi.nlm.nih.gov/26625143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiological effects of peroxynitrite: potential products of the environment

1 reference

https://pubmed.ncbi.nlm.nih.gov/26625143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endotoxin induces toll-like receptor 4 expression in vascular smooth muscle cells via NADPH oxidase activation and mitogen-activated protein kinase signaling pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/26625143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypercholesterolemia accelerates vascular calcification induced by excessive vitamin D via oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/26625143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0143686

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

2015PLoSO..1043686L

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q35857300&oldid=1854320531"