(Q35860311)

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Beneficial Effects of Evogliptin, a Novel Dipeptidyl Peptidase 4 Inhibitor, on Adiposity with Increased Ppargc1a in White Adipose Tissue in Obese Mice

scientific article published on 3 December 2015

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Europe PubMed Central

PMC publication ID

10 August 2017

Beneficial Effects of Evogliptin, a Novel Dipeptidyl Peptidase 4 Inhibitor, on Adiposity with Increased Ppargc1a in White Adipose Tissue in Obese Mice (English)

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Europe PubMed Central

PMC publication ID

10 August 2017

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Yu-Na Chae

1

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Europe PubMed Central

PMC publication ID

10 August 2017

Tae-Hyoung Kim

2

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Europe PubMed Central

PMC publication ID

10 August 2017

Mi-Kyung Kim

3

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Europe PubMed Central

PMC publication ID

10 August 2017

Chang-Yell Shin

4

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Europe PubMed Central

PMC publication ID

10 August 2017

Il-Hoon Jung

5

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Europe PubMed Central

PMC publication ID

10 August 2017

Yong Sung Sohn

6

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PMC publication ID

10 August 2017

Moon-Ho Son

7

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10 August 2017

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publication date

3 December 2015

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Europe PubMed Central

PMC publication ID

10 August 2017

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Europe PubMed Central

PMC publication ID

10 August 2017

10

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Europe PubMed Central

PMC publication ID

10 August 2017

12

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

e0144064

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Europe PubMed Central

PMC publication ID

10 August 2017

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Creative Commons Attribution 4.0 International

3 December 2015

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4669177/fullTextXML

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Induction of Energy Expenditure by Sitagliptin Is Dependent on GLP-1 Receptor

1 reference

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11 July 2018

Adipose tissue browning and metabolic health

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669177

11 July 2018

Saxagliptin Improves Glucose Tolerance but not Survival in a Murine Model of Dilated Cardiomyopathy

1 reference

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11 July 2018

Emerging gliptins for type 2 diabetes

1 reference

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11 July 2018

Treatment outcomes after initiation of exenatide twice daily or insulin in clinical practice: 12-month results from CHOICE in six European countries

1 reference

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11 July 2018

Effects of LX4211, a dual SGLT1/SGLT2 inhibitor, plus sitagliptin on postprandial active GLP-1 and glycemic control in type 2 diabetes

1 reference

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11 July 2018

Brown adipose tissue and its modulation by a mitochondria-targeted peptide in rat burn injury-induced hypermetabolism

1 reference

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11 July 2018

Impaired protein metabolism: interlinks between obesity, insulin resistance and inflammation

1 reference

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11 July 2018

Dipeptidyl-peptidase-IV by cleaving neuropeptide Y induces lipid accumulation and PPAR-γ expression.

1 reference

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11 July 2018

Linagliptin improves insulin sensitivity and hepatic steatosis in diet-induced obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669177

11 July 2018

Alterations in energy balance following exenatide administration

1 reference

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11 July 2018

Indirect calorimetry in laboratory mice and rats: principles, practical considerations, interpretation and perspectives

1 reference

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11 July 2018

Regulation of adipocyte formation by GLP-1/GLP-1R signaling

1 reference

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11 July 2018

A review of gliptins in 2011.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669177

11 July 2018

Study of the potential association of adipose tissue GLP-1 receptor with obesity and insulin resistance

1 reference

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11 July 2018

Dipeptidyl peptidase 4 is a novel adipokine potentially linking obesity to the metabolic syndrome

1 reference

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11 July 2018

Perilipin Overexpression in White Adipose Tissue Induces a Brown Fat-Like Phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669177

11 July 2018

A novel dipeptidyl peptidase IV inhibitor DA-1229 ameliorates streptozotocin-induced diabetes by increasing β-cell replication and neogenesis

1 reference

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11 July 2018

Dipeptidyl peptidase IV inhibitor sitagliptin reduces local inflammation in adipose tissue and in pancreatic islets of obese mice

1 reference

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11 July 2018

Peripherally acting CB1-receptor antagonist: the relative importance of central and peripheral CB1 receptors in adiposity control

1 reference

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11 July 2018

Conjugated linoleic acid induces uncoupling protein 1 in white adipose tissue of ob/ob mice

1 reference

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11 July 2018

Prolonged AICAR-induced AMP-kinase activation promotes energy dissipation in white adipocytes: novel mechanisms integrating HSL and ATGL

1 reference

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11 July 2018

Efficacy and safety of incretin therapy in type 2 diabetes: systematic review and meta-analysis

1 reference

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11 July 2018

PGC-1alpha: a key regulator of energy metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669177

11 July 2018

PGC-1 coactivators: inducible regulators of energy metabolism in health and disease

1 reference

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11 July 2018

Pharmacokinetic and pharmacodynamic properties of multiple oral doses of sitagliptin, a dipeptidyl peptidase-IV inhibitor: a double-blind, randomized, placebo-controlled study in healthy male volunteers

1 reference

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11 July 2018

Direct metabolic regulation in skeletal muscle and fat tissue by leptin: implications for glucose and fatty acids homeostasis

1 reference

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11 July 2018

Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1

1 reference

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Mice lacking dipeptidyl peptidase IV are protected against obesity and insulin resistance

1 reference

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11 July 2018

Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres

1 reference

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11 July 2018

Healthy body weights: an alternative perspective

1 reference

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11 July 2018

Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks

1 reference

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11 July 2018

Dipeptidyl peptidase-4 inhibitor, vildagliptin, inhibits pancreatic beta cell apoptosis in association with its effects suppressing endoplasmic reticulum stress in db/db mice.

1 reference

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24 September 2018

Relative shrinkage of adipocytes by paraffin in proportion to plastic embedding in human adipose tissue before and after weight loss

1 reference

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The novel dipeptidyl peptidase-4 inhibitor teneligliptin prevents high-fat diet-induced obesity accompanied with increased energy expenditure in mice.

1 reference

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The once-daily human GLP-1 analogue liraglutide impacts appetite and energy intake in patients with type 2 diabetes after short-term treatment

1 reference

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Vildagliptin preserves the mass and function of pancreatic β cells via the developmental regulation and suppression of oxidative and endoplasmic reticulum stress in a mouse model of diabetes

1 reference

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Glucagon-like peptide-1 agonist exendin-4 leads to reduction of weight and caloric intake in a rat model of hypothalamic obesity

1 reference

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Effect of the once-daily human GLP-1 analogue liraglutide on appetite, energy intake, energy expenditure and gastric emptying in type 2 diabetes.

1 reference

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DA-1229, a novel and potent DPP4 inhibitor, improves insulin resistance and delays the onset of diabetes.

1 reference

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24 September 2018

Altered dipeptidyl peptidase-4 activity during the progression of hyperinsulinemic obesity and islet atrophy in spontaneously late-stage type 2 diabetic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669177

24 September 2018

Comparative effects of telmisartan, sitagliptin and metformin alone or in combination on obesity, insulin resistance, and liver and pancreas remodelling in C57BL/6 mice fed on a very high-fat diet

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669177

24 September 2018

Dysregulation of lipolysis and lipid metabolism in visceral and subcutaneous adipocytes by high-fat diet: role of ATGL, HSL, and AMPK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669177

24 September 2018

Inhibition of DPP-4 with sitagliptin improves glycemic control and restores islet cell mass and function in a rodent model of type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669177

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Increased plasma dipeptidyl peptidase IV (DPP IV) activity and decreased DPP IV activity of visceral but not subcutaneous adipose tissue in impaired glucose tolerance rats induced by high-fat or high-sucrose diet

1 reference

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DPP-IV inhibition enhances the antilipolytic action of NPY in human adipose tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669177

24 September 2018

Dipeptidyl-peptidase-IV inhibition augments postprandial lipid mobilization and oxidation in type 2 diabetic patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669177

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Differential antidiabetic efficacy of incretin agonists versus DPP-4 inhibition in high fat fed mice

1 reference

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24 September 2018

Incretin receptors for glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide are essential for the sustained metabolic actions of vildagliptin in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669177

24 September 2018

Relationship between adipocyte size and adipokine expression and secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669177

24 September 2018

Higher fasting plasma concentrations of glucagon-like peptide 1 are associated with higher resting energy expenditure and fat oxidation rates in humans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669177

24 September 2018

Antiobesity action of peripheral exenatide (exendin-4) in rodents: effects on food intake, body weight, metabolic status and side-effect measures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669177

24 September 2018

Peripheral exendin-4 and peptide YY(3-36) synergistically reduce food intake through different mechanisms in mice

1 reference

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Pioglitazone induces mitochondrial biogenesis in human subcutaneous adipose tissue in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669177

24 September 2018

Oxyntomodulin and glucagon-like peptide-1 differentially regulate murine food intake and energy expenditure

1 reference

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Validation of housekeeping genes for normalizing RNA expression in real-time PCR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4669177

24 September 2018

The effect of glucagon-like peptide-1 on energy expenditure and substrate metabolism in humans

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0144064

21 January 2018

PGC1-α over-expression prevents metabolic alterations and soleus muscle atrophy in hindlimb unloaded mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/26633898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic treatment with the dipeptidyl peptidase-4 inhibitor BI 1356 [(R)-8-(3-amino-piperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydro-purine-2,6-dione] increases basal glucagon-like peptide-1 and improves glycemic

1 reference

https://pubmed.ncbi.nlm.nih.gov/26633898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discovery of DA-1229: a potent, long acting dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/26633898

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0144064

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

2015PLoSO..1044064C

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

ResearchGate publication ID

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