(Q42480141)

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A novel dipeptidyl peptidase IV inhibitor DA-1229 ameliorates streptozotocin-induced diabetes by increasing β-cell replication and neogenesis

scientific article published on November 18, 2010

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Europe PubMed Central

PubMed publication ID

1 November 2017

A novel dipeptidyl peptidase IV inhibitor DA-1229 ameliorates streptozotocin-induced diabetes by increasing β-cell replication and neogenesis (English)

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Europe PubMed Central

PubMed publication ID

1 November 2017

author name string

Jae Min Cho

1

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Europe PubMed Central

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1 November 2017

Hye Won Jang

2

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Europe PubMed Central

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1 November 2017

Hwanju Cheon

3

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Europe PubMed Central

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1 November 2017

Yeon Taek Jeong

4

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Europe PubMed Central

PubMed publication ID

1 November 2017

Do-Hoon Kim

5

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Europe PubMed Central

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1 November 2017

Yu-Mi Lim

6

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Europe PubMed Central

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1 November 2017

Song-Hyen Choi

7

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Europe PubMed Central

PubMed publication ID

1 November 2017

Eun-Kyoung Yang

8

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Europe PubMed Central

PubMed publication ID

1 November 2017

Chang-Yell Shin

9

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Europe PubMed Central

PubMed publication ID

1 November 2017

Moon Ho Son

10

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Europe PubMed Central

PubMed publication ID

1 November 2017

Soon Hoe Kim

11

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Europe PubMed Central

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1 November 2017

Heung-Jae Kim

12

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Europe PubMed Central

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1 November 2017

Myung-Shik Lee

13

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Europe PubMed Central

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1 November 2017

language of work or name

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National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21093089

31 August 2024

publication date

18 November 2010

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1 November 2017

full work available at URL

https://api.elsevier.com/content/article/PII:S0168822710005462?httpAccept=text/xml

1 reference

10.1016/J.DIABRES.2010.10.012

https://api.crossref.org/works/10.1016/J.DIABRES.2010.10.012

31 August 2024

https://api.elsevier.com/content/article/PII:S0168822710005462?httpAccept=text/plain

1 reference

10.1016/J.DIABRES.2010.10.012

https://api.crossref.org/works/10.1016/J.DIABRES.2010.10.012

31 August 2024

Diabetes Research and Clinical Practice

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Europe PubMed Central

PubMed publication ID

1 November 2017

91

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Europe PubMed Central

PubMed publication ID

1 November 2017

1

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Europe PubMed Central

PubMed publication ID

1 November 2017

72-79

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Europe PubMed Central

PubMed publication ID

1 November 2017

Type 1 diabetes: new perspectives on disease pathogenesis and treatment

1

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Redefining the clinical management of type 2 diabetes: matching therapy to pathophysiology

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Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats

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Chronic inhibition of dipeptidyl peptidase-4 with a sitagliptin analog preserves pancreatic beta-cell mass and function in a rodent model of type 2 diabetes.

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Dipeptidyl peptidase-4 inhibitors: clinical data and clinical implications

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Dipeptidyl peptidase IV inhibitor treatment stimulates beta-cell survival and islet neogenesis in streptozotocin-induced diabetic rats.

10

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Synthesis and evaluation of pyrazolidine derivatives as dipeptidyl peptidase IV (DP-IV) inhibitors

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Apoptosis of pancreatic beta-cells detected in accelerated diabetes of NOD mice: no role of Fas-Fas ligand interaction in autoimmune diabetes

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Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia

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Extra-insular beta cells associated with ductules are frequent in adult human pancreas

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Glucagon-like peptide 1 receptor agonist ZP10A increases insulin mRNA expression and prevents diabetic progression in db/db mice

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Glucagon-like peptide-1 and islet lipolysis

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In vivo expression of GLP-1/IgG-Fc fusion protein enhances beta-cell mass and protects against streptozotocin-induced diabetes

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Glucagon-like peptide-1 activation of TCF7L2-dependent Wnt signaling enhances pancreatic beta cell proliferation

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beta-Cell Pdx1 expression is essential for the glucoregulatory, proliferative, and cytoprotective actions of glucagon-like peptide-1.

22

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Glucagon-like peptide I reduces postprandial glycemic excursions in IDDM

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Antidiabetogenic effect of glucagon-like peptide-1 (7-36)amide in normal subjects and patients with diabetes mellitus

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Glucagonostatic actions and reduction of fasting hyperglycemia by exogenous glucagon-like peptide I(7-36) amide in type I diabetic patients.

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Islet beta cell failure in type 2 diabetes

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Enhanced expression of PDX-1 and Ngn3 by exendin-4 during beta cell regeneration in STZ-treated mice.

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Glucagon-like peptide-1 receptor signaling modulates beta cell apoptosis

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Preservation of beta-cell function by targeting beta-cell mass

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Exendin-4 improves reversal of diabetes in NOD mice treated with anti-CD3 monoclonal antibody by enhancing recovery of beta-cells

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Cure of overt diabetes in NOD mice by transient treatment with anti-lymphocyte serum and exendin-4.

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Anti-inflammatory action of exendin-4 in human islets is enhanced by phosphodiesterase inhibitors: potential therapeutic benefits in diabetic patients

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Identifiers

10.1016/J.DIABRES.2010.10.012

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

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