(Q35871814)

10 August 2017

Sedation and histamine H1-receptor antagonism: studies in man with the enantiomers of chlorpheniramine and dimethindene (English)

1 reference

10 August 2017

1 reference

1 reference

1 reference

https://api.crossref.org/works/10.1111/J.1476-5381.1991.TB12418.X

29 October 2022

author name string

A. N. Nicholson

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1686208

29 October 2022

P. A. Pascoe

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1686208

29 October 2022

C. Turner

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1686208

29 October 2022

C. R. Ganellin

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1686208

29 October 2022

P. M. Greengrass

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1686208

29 October 2022

A. F. Casy

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1686208

29 October 2022

A. D. Mercer

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1686208

29 October 2022

language of work or name

English

0 references

publication date

1 September 1991

1 reference

PMCID

1908262

full work available at URL

10 August 2017

https://europepmc.org/articles/PMC1908262

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1686208

https://europepmc.org/articles/PMC1908262?pdf=render

29 October 2022

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1686208

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1476-5381.1991.tb12418.x

29 October 2022

1 reference

https://api.crossref.org/works/10.1111/J.1476-5381.1991.TB12418.X

http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1476-5381.1991.tb12418.x/fullpdf

29 October 2022

1 reference

https://api.crossref.org/works/10.1111/J.1476-5381.1991.TB12418.X

British Journal of Pharmacology

29 October 2022

published in

1 reference

10 August 2017

104

1 reference

10 August 2017

1

1 reference

10 August 2017

270-276

1 reference

Evaluation of the CNS properties of SCH 29851, a potential non-sedating antihistamine

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Antihistaminic activity and central effects of terfenadine. A review of European studies

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Performance studies with the H1-histamine receptor antagonists, astemizole and terfenadine

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Catecholamine uptake by synaptosomes from rat brain. Structure-activity relationships of drugs with differential effects on dopamine and norepinephrine neurons

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Inhibition of dopamine uptake into synaptosomes of rat corpus striatum by chlorpheniramine and its structural analogs

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Antiparkinsonian drugs and central dopamine neurons.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

The effect of pheniramine and its structural analogues on 5-hydroxytryptamine in rat and mouse brain

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Quantification of Sleepiness: A New Approach

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

A comparison of the EEG effects of the potent antihistaminic (DL-chlorpheniramine) with a less potent isomer (L-chlorpheniramine).

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

The effect of imipramine-like drugs and antihistamine drugs on uptake mechanisms in the central noradrenaline and 5-hydroxytryptamine neurons.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Effect of some antiparkinsonian drugs on catecholamine neurons.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Central and peripheral monoaminergic membrane-pump blockade by some addictive analgesics and antihistamines

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Muscarinic cholinergic binding in rat brain

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Electroencephalographic, behavioural and visceral effects of intraventricular infusion of histamine in the rabbit

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Importance of drug enantiomers in clinical pharmacology

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Antihistamines: impaired performance and the tendency to sleep.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Stereoselectivity: an issue of significant importance in clinical pharmacology

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Evidence for histaminergic arousal mechanisms in the hypothalamus of cat.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Inhibition by H1-antihistamines of the uptake of noradrenaline and 5-HT into rat brain synaptosomes.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Studies on the central effects of the H1-antagonist, loratadine

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Antimuscarinic effects of antihistamines: quantitative evaluation by receptor-binding assay

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Pharmacological studies with SK&F 93944 (temelastine), a novel histamine H1-receptor antagonist with negligible ability to penetrate the central nervous system

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Selective displacement of [3H]mepyramine from peripheral vs. central nervous system receptors by loratadine, a non-sedating antihistamine

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Peripheral antihistamine and central sedative effects of three H1-receptor antagonists

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Histaminergic systems and sleep. Studies in man with H1 and H2 antagonists.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

A comparison of triprolidine and clemastine on histamine antagonism and performance tests in man: Implications for the mechanism of drug induced drowsiness

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Stereoisomers of an antihistamine and the pharmacologic receptors of rabbit aorta

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Hypothalamic 24-Hour Rhythms in Histamine, Histidine Decarboxylase and Histamine-N-Methyltransferase*

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Adipocyte beta-adrenergic receptors. Identification and subcellular localization by (-)-[3H]dihydroalprenolol binding

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

The binding of [3H]mepyramine to histamine H1 receptors in guinea-pig brain

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Multiple serotonin receptors: differential binding of [3H]5-hydroxytryptamine, [3H]lysergic acid diethylamide and [3H]spiroperidol

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Heterogeneity of histamine H1-receptors: species variations in [3H]mepyramine binding of brain membranes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Histamine H1 receptors identified in mammalian brain membranes with [3H]mepyramine

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

In vivo occupation of cerebral histamine H1-receptors evaluated with 3H-mepyramine may predict sedative properties of psychotropic drugs

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Binding characteristics of 3H-prazosin to rat brain α-adrenergic receptors

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Performance studies with antihistamines

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Spiperone: a ligand of choice for neuroleptic receptors. 1. Kinetics and characteristics of in vitro binding

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

pD2-, pA2- and pD2′-values of series of compounds in a histaminic and a cholinergic system

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Neurochemical evidence for histamine acting as a transmitter in mammalian brain

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

[3H]Ketanserin (R 41 468), a selective 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain distribution, and functional role.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Binding of the imidazoline UK-14, 304, a putative full α2-adrenoceptor agonist, to rat cerebral cortex membranes

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Kinetics of [3H]flunitrazepam binding to membrane-bound benzodiazepine receptors.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Circadian rhythms in rat mid-brain and caudate nucleus biogenic amine levels.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1908262

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

24 September 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.1991.TB12418.X

New Tables for Multiple Comparisons with a Control

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.1991.TB12418.X

Antihistamines and sedation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.1991.TB12418.X

Comparative pharmacology of chlorpheniramine (Chlor-Trimeton) and its optical isomers

21 January 2018

1 reference

12 December 2020

Pharmacodynamic and pharmacokinetic differences between drug enantiomers in humans: an overview

1 reference

12 December 2020

[Behavior of chlorpheniramine in vivo after administration of d- and l-chlorpheniramine maleate]

1 reference

12 December 2020

Effects of H1- and H2-histamine receptor agonists and antagonists on sleep and wakefulness in the rat

1 reference

12 December 2020

Influence of substrate configuration on chlorpheniramine N-demethylation by hepatic microsomes from rats, rabbits, and mice

1 reference

12 December 2020

Labeling of histamine H1-receptors in the brain of the living mouse

1 reference

12 December 2020

The H1-antagonist mequitazine: studies on performance and visual function

1 reference

12 December 2020

Mass fragmentographic determination of d- and l-chloropheniramine with aid of the stable isotope technique

1 reference

12 December 2020

A pharmacologic investigation of dimethpyrindene maleate (Forhistal)

1 reference

12 December 2020

An Analysis of Transformations

6

1 reference

https://api.crossref.org/works/10.1111/J.1476-5381.1991.TB12418.X

29 October 2022

Identifiers

1 reference

10 August 2017

1 reference

10 August 2017

1 reference

PMCID

1908262