(Q35874524)

English

Constitutive expression of inter-α-inhibitor (IαI) family proteins and tumor necrosis factor-stimulated gene-6 (TSG-6) by human amniotic membrane epithelial and stromal cells supporting formation of the heavy chain-hyaluronan (HC-HA) complex.

scientific article published on 20 February 2012

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23 January 2020

Constitutive expression of inter-α-inhibitor (IαI) family proteins and tumor necrosis factor-stimulated gene-6 (TSG-6) by human amniotic membrane epithelial and stromal cells supporting formation of the heavy chain-hyaluronan (HC-HA) complex (English)

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23 January 2020

3

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23 January 2020

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Suzhen Zhang

1

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23 January 2020

Hua He

2

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23 January 2020

Scheffer C G Tseng

4

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20 February 2012

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23 January 2020

Journal of Biological Chemistry

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23 January 2020

287

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23 January 2020

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23 January 2020

12433-12444

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23 January 2020

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11 June 2022

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Hyaluronan, TSG-6, and inter-α-inhibitor in periprosthetic breast capsules: reduced levels of free hyaluronan and TSG-6 expression in contracted capsules.

1 reference

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Characterization of hyaluronan and TSG-6 in skin scarring: differential distribution in keloid scars, normal scars and unscarred skin.

1 reference

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Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6

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1 reference

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1 reference

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11 July 2018

Suppression of activation and induction of apoptosis in RAW264.7 cells by amniotic membrane extract.

1 reference

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11 July 2018

Human amniotic epithelial cells as novel feeder layers for promoting ex vivo expansion of limbal epithelial progenitor cells

1 reference

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11 July 2018

Amniotic membrane transplantation in the management of severe ocular surface disease: indications and outcomes.

1 reference

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11 July 2018

How does amniotic membrane work?

1 reference

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11 July 2018

TSG-6 potentiates the antitissue kallikrein activity of inter-alpha-inhibitor through bikunin release.

1 reference

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11 July 2018

SHAP potentiates the CD44-mediated leukocyte adhesion to the hyaluronan substratum.

1 reference

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11 July 2018

Characterization of complexes formed between TSG-6 and inter-alpha-inhibitor that act as intermediates in the covalent transfer of heavy chains onto hyaluronan.

1 reference

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11 July 2018

Hyaluronic acid-CD44 interaction mediates the adhesion of lymphocytes by amniotic membrane stroma.

1 reference

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11 July 2018

The TSG-6 and I alpha I interaction promotes a transesterification cleaving the protein-glycosaminoglycan-protein (PGP) cross-link.

1 reference

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11 July 2018

TNFalpha-stimulated gene product (TSG-6) and its binding protein, IalphaI, in the human intervertebral disc: new molecules for the disc.

1 reference

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Inter-alpha-trypsin inhibitor, a covalent protein-glycosaminoglycan-protein complex

1 reference

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11 July 2018

The amniotic membrane in ophthalmology.

1 reference

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11 July 2018

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11 July 2018

Induction of the hyaluronic acid-binding protein, tumor necrosis factor-stimulated gene-6, in cervical smooth muscle cells by tumor necrosis factor-alpha and prostaglandin E(2).

1 reference

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11 July 2018

Amniotic membrane transplantation for ocular surface reconstruction

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11 July 2018

A novel allelic variant of the human TSG-6 gene encoding an amino acid difference in the CUB module. Chromosomal localization, frequency analysis, modeling, and expression

1 reference

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11 July 2018

Hyaluronan-binding proteins: tying up the giant

1 reference

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11 July 2018

Expression of inter-alpha-trypsin inhibitor and tumor necrosis factor-stimulated gene 6 in renal proximal tubular epithelial cells.

1 reference

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Profiling changes in gene expression during differentiation and maturation of monocyte-derived dendritic cells using both oligonucleotide microarrays and proteomics

1 reference

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11 July 2018

Immunohistochemical distribution of inter-alpha-trypsin inhibitor chains in normal and malignant human lung tissue

1 reference

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11 July 2018

ITIH4 serum concentration increases during acute-phase processes in human patients and is up-regulated by interleukin-6 in hepatocarcinoma HepG2 cells

1 reference

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11 July 2018

Intracellular proteolytic processing of the heavy chain of rat pre-alpha-inhibitor. The COOH-terminal propeptide is required for coupling to bikunin

1 reference

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11 July 2018

Human inter-alpha-trypsin inhibitor heavy chain H3 gene. Genomic organization, promoter analysis, and gene linkage

1 reference

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11 July 2018

Glycosylation pattern of human inter-alpha-inhibitor heavy chains

1 reference

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11 July 2018

Gene expression of the two heavy chains and one light chain forming the inter-alpha-trypsin-inhibitor in human tissues

1 reference

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11 July 2018

Complexity of IL-1 beta induced gene expression pattern in human articular chondrocytes

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11 July 2018

TSG-6 expression in human articular chondrocytes. Possible implications in joint inflammation and cartilage degradation

1 reference

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11 July 2018

Development of an enzyme-linked immunosorbent assay for human plasma inter-alpha-trypsin inhibitor (ITI) using specific antibodies against each of the H1 and H2 heavy chains

1 reference

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11 July 2018

Transcriptional regulation of TSG6, a tumor necrosis factor- and interleukin-1-inducible primary response gene coding for a secreted hyaluronan-binding protein.

1 reference

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11 July 2018

Effects of exogenous hyaluronic acid and serum on matrix organization and stability in the mouse cumulus cell-oocyte complex.

1 reference

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11 July 2018

TSG-6: a TNF-, IL-1-, and LPS-inducible secreted glycoprotein associated with arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320993

11 July 2018

Human inter-α-inhibitor family in inflammation: simultaneous synthesis of positive and negative acute-phase proteins

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11 July 2018

Evidence for the Covalent Binding of SHAP, Heavy Chains of Inter-α-Trypsin Inhibitor, to Hyaluronan

1 reference

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11 July 2018

Biosynthesis of bikunin proteins in the human carcinoma cell line HepG2 and in primary human hepatocytes. Polypeptide assembly by glycosaminoglycan

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320993

11 July 2018

Proteins of the inter-alpha-trypsin inhibitor family stabilize the cumulus extracellular matrix through their direct binding with hyaluronic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320993

11 July 2018

Post-translational processing of the inter-α-trypsin inhibitor in the human hepatoma HepG2 cell line

1 reference

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11 July 2018

Isolation and characterization of the human inter-alpha-trypsin inhibitor heavy-chain H1 gene

1 reference

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11 July 2018

Analysis of inter-alpha-trypsin inhibitor and a novel trypsin inhibitor, pre-alpha-trypsin inhibitor, from human plasma. Polypeptide chain stoichiometry and assembly by glycan

1 reference

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11 July 2018

Carbohydrate as covalent crosslink in human inter-alpha-trypsin inhibitor: a novel plasma protein structure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320993

11 July 2018

Isolation and characterization of eight tumor necrosis factor-induced gene sequences from human fibroblasts

1 reference

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11 July 2018

Chondroitin 4-sulfate covalently cross-links the chains of the human blood protein pre-alpha-inhibitor

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11 July 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320993

11 July 2018

Inter-alpha-trypsin inhibitor and pre-alpha-trypsin inhibitor in health and disease. Determination by immunoelectrophoresis and immunoblotting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320993

11 July 2018

Hyaluronic acid associated with the surfaces of cultured fibroblasts is linked to a serum-derived 85-kDa protein

1 reference

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11 July 2018

Superficial zone chondrocytes in normal and osteoarthritic human articular cartilages synthesize novel truncated forms of inter-alpha-trypsin inhibitor heavy chains which are attached to a chondroitin sulfate proteoglycan other than bikunin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320993

24 September 2018

The transfer of heavy chains from bikunin proteins to hyaluronan requires both TSG-6 and HC2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320993

24 September 2018

Equivalent involvement of inter-alpha-trypsin inhibitor heavy chain isoforms in forming covalent complexes with hyaluronan

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320993

24 September 2018

Hyaluronan cross-linking: a protective mechanism in inflammation?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320993

24 September 2018

Covalent transfer of heavy chains of inter-alpha-trypsin inhibitor family proteins to hyaluronan in in vivo and in vitro expanded porcine oocyte-cumulus complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320993

24 September 2018

ITIH5, a novel member of the inter-alpha-trypsin inhibitor heavy chain family is downregulated in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320993

24 September 2018

Molecular heterogeneity of the SHAP-hyaluronan complex. Isolation and characterization of the complex in synovial fluid from patients with rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320993

24 September 2018

Impaired cumulus mucification and female sterility in tumor necrosis factor-induced protein-6 deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320993

24 September 2018

Role of tumour necrosis factor stimulated gene 6 (TSG-6) in the coupling of inter-alpha-trypsin inhibitor to hyaluronan in human follicular fluid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320993

24 September 2018

Two distinct populations of tumor necrosis factor-stimulated gene-6 protein in the extracellular matrix of expanded mouse cumulus cell-oocyte complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320993

24 September 2018

Proteoglycans and hyaluronan in human fetal membranes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320993

24 September 2018

Defect in SHAP-hyaluronan complex causes severe female infertility. A study by inactivation of the bikunin gene in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320993

24 September 2018

Covalent linkage between proteins of the inter-alpha-inhibitor family and hyaluronic acid is mediated by a factor produced by granulosa cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320993

24 September 2018

Biosynthesis of bikunin (urinary trypsin inhibitor) in rat hepatocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.342873

21 January 2018

Structural Characterization of Inter-α-inhibitor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.342873

21 January 2018

Isolation and characterization of an inter-alpha-trypsin inhibitor-IgG complex from human serum

1 reference

https://pubmed.ncbi.nlm.nih.gov/22351758

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and characterization of urinary trypsin inhibitor, UTI68, from normal human urine, and its cleavage by human uropepsin

1 reference

https://pubmed.ncbi.nlm.nih.gov/22351758

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and characterization of a novel substrate for plasma kallikrein (PK-120) in human plasma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22351758

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electrophoretic pattern of the inter-alpha-inhibitor family proteins in human serum, characterized by chain-specific antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/22351758

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo binding of human inter-alpha-trypsin inhibitor free heavy chains to hyaluronic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/22351758

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired fertility in female mice lacking urinary trypsin inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/22351758

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assembly and secretion of recombinant chains of human inter-alpha-trypsin inhibitor in COS-7 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22351758

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.342873

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22351758%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22351758%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22351758%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

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