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English
Catalytic and framework mutations in the neuraminidase active site of influenza viruses that are resistant to 4-guanidino-Neu5Ac2en.
scientific article published in May 1997
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
191482
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9094607%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
title
Catalytic and framework mutations in the neuraminidase active site of influenza viruses that are resistant to 4-guanidino-Neu5Ac2en
(English)
1 reference
stated in
Europe PubMed Central
PMCID
191482
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9094607%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
author
Robert G. Webster
series ordinal
4
object named as
R G Webster
1 reference
stated in
Europe PubMed Central
PMCID
191482
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9094607%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
author name string
L V Gubareva
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
191482
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9094607%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
M J Robinson
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
191482
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9094607%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
R C Bethell
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
191482
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9094607%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
language of work or name
English
0 references
publication date
1 May 1997
1 reference
stated in
Europe PubMed Central
PMCID
191482
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9094607%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
published in
Journal of Virology
1 reference
stated in
Europe PubMed Central
PMCID
191482
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9094607%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
volume
71
1 reference
stated in
Europe PubMed Central
PMCID
191482
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9094607%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
page(s)
3385-3390
1 reference
stated in
Europe PubMed Central
PMCID
191482
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9094607%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
issue
5
1 reference
stated in
Europe PubMed Central
PMCID
191482
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9094607%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
cites work
Mutation in the influenza virus neuraminidase gene resulting in decreased sensitivity to the neuraminidase inhibitor 4-guanidino-Neu5Ac2en leads to instability of the enzyme
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191482
retrieved
27 July 2018
Characterization of mutants of influenza A virus selected with the neuraminidase inhibitor 4-guanidino-Neu5Ac2en
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191482
retrieved
27 July 2018
GG167 (4-guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid) is a potent inhibitor of influenza virus in ferrets
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191482
retrieved
27 July 2018
Molecular basis for the resistance of influenza viruses to 4-guanidino-Neu5Ac2en
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191482
retrieved
27 July 2018
Generation and characterization of an influenza virus neuraminidase variant with decreased sensitivity to the neuraminidase-specific inhibitor 4-guanidino-Neu5Ac2en
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191482
retrieved
27 July 2018
Safety and efficacy of the neuraminidase inhibitor GG167 in experimental human influenza
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191482
retrieved
27 July 2018
Rational design of potent sialidase-based inhibitors of influenza virus replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191482
retrieved
27 July 2018
Sequence and structure alignment of paramyxovirus hemagglutinin-neuraminidase with influenza virus neuraminidase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191482
retrieved
27 July 2018
Three-dimensional structure of influenza A N9 neuraminidase and its complex with the inhibitor 2-deoxy 2,3-dehydro-N-acetyl neuraminic acid
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191482
retrieved
27 July 2018
4-Guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid is a highly effective inhibitor both of the sialidase (neuraminidase) and of growth of a wide range of influenza A and B viruses in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191482
retrieved
27 July 2018
Molecular modeling studies on ligand binding to sialidase from influenza virus and the mechanism of catalysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191482
retrieved
27 July 2018
Influenza B virus neuraminidase can synthesize its own inhibitor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191482
retrieved
27 July 2018
A sialic acid-derived phosphonate analog inhibits different strains of influenza virus neuraminidase with different efficiencies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191482
retrieved
27 July 2018
Inhibition of influenza virus replication in mice by GG167 (4-guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid) is consistent with extracellular activity of viral neuraminidase (sialidase)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191482
retrieved
27 July 2018
Influenza type A virus neuraminidase does not play a role in viral entry, replication, assembly, or budding
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191482
retrieved
27 July 2018
Inhibition of replication of avian influenza viruses by the neuraminidase inhibitor 4-guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191482
retrieved
27 July 2018
Three-dimensional structure of the complex of 4-guanidino-Neu5Ac2en and influenza virus neuraminidase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191482
retrieved
27 July 2018
Plaque inhibition assay for drug susceptibility testing of influenza viruses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191482
retrieved
27 July 2018
Structure of the influenza virus glycoprotein antigen neuraminidase at 2.9 A resolution
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191482
retrieved
27 July 2018
Influenzavirus neuraminidase and neuraminidase-inhibition test procedures
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191482
retrieved
27 July 2018
Three-dimensional structure of neuraminidase of subtype N9 from an avian influenza virus.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191482
retrieved
27 July 2018
Site-directed mutation of the active site of influenza neuraminidase and implications for the catalytic mechanism.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191482
retrieved
27 July 2018
Biologic potential of amantadine-resistant influenza A virus in an avian model
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191482
retrieved
27 July 2018
The neuraminidase of influenza virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191482
retrieved
27 July 2018
Three-dimensional structure of the neuraminidase of influenza virus A/Tokyo/3/67 at 2.2 A resolution
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191482
retrieved
27 July 2018
The structure of the complex between influenza virus neuraminidase and sialic acid, the viral receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191482
retrieved
27 July 2018
Inhibition of influenza virus replication in tissue culture by 2-deoxy-2,3-dehydro-N-trifluoroacetylneuraminic acid (FANA): mechanism of action
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191482
retrieved
27 July 2018
Synthesis of 2'-(4-methylumbelliferyl)-.alpha.-D-N-acetylneuraminic acid and detection of skin fibroblast neuraminidase in normal humans and in sialidosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191482
retrieved
27 July 2018
Crystal structure of a bacterial sialidase (from Salmonella typhimurium LT2) shows the same fold as an influenza virus neuraminidase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191482
retrieved
24 September 2018
Influenza virus neuraminidase: structure, antibodies, and inhibitors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191482
retrieved
24 September 2018
Newcastle disease virus contains a linkage-specific glycoprotein sialidase. Application to the localization of sialic acid residues in N-linked oligosaccharides of alpha 1-acid glycoprotein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191482
retrieved
24 September 2018
Antigenic hybrids of influenza a viruses with surface antigens to order
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9094607
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/JVI.71.5.3385-3390.1997
0 references
PMCID
191482
1 reference
stated in
Europe PubMed Central
PMCID
191482
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9094607%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
PubMed ID
9094607
1 reference
stated in
Europe PubMed Central
PMCID
191482
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9094607%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
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