(Q35882594)

English

Dissecting the genetics of the human transcriptome identifies novel trait-related trans-eQTLs and corroborates the regulatory relevance of non-protein coding loci†.

scientific article published on 27 May 2015

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scholarly article

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Europe PubMed Central

10 August 2017

Dissecting the genetics of the human transcriptome identifies novel trait-related trans-eQTLs and corroborates the regulatory relevance of non-protein coding loci†. (English)

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10 August 2017

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Ralph Burkhardt

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Jörg Hackermüller

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Hoor Al-Hasani

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Lesca Holdt

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Frank Beutner

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Knut Krohn

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Markus Löffler

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Markus Scholz

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Daniel Teupser

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Joachim Thiery

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publication date

27 May 2015

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Human Molecular Genetics

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12 June 2020

4746-4763

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12 June 2020

Heritability and genomics of gene expression in peripheral blood

1 reference

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Cell cycle, oncogenic and tumor suppressor pathways regulate numerous long and macro non-protein-coding RNAs

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rSNPBase: a database for curated regulatory SNPs

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Genetic associations with expression for genes implicated in GWAS studies for atherosclerotic cardiovascular disease and blood phenotypes

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Systematic identification of trans eQTLs as putative drivers of known disease associations

1 reference

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Alu elements in ANRIL non-coding RNA at chromosome 9p21 modulate atherogenic cell functions through trans-regulation of gene networks

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Congruence of additive and non-additive effects on gene expression estimated from pedigree and SNP data

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The genomic signature of trait-associated variants.

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Human disease-associated genetic variation impacts large intergenic non-coding RNA expression

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Transcription factor and chromatin features predict genes associated with eQTLs

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Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population

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An integrated map of genetic variation from 1,092 human genomes

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The GENCODE pseudogene resource

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Protein degradation pathways in Parkinson's disease: curse or blessing

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Impact of common regulatory single-nucleotide variants on gene expression profiles in whole blood

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Matrix eQTL: ultra fast eQTL analysis via large matrix operations

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Statistical colocalization of monocyte gene expression and genetic risk variants for type 1 diabetes

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Exon-specific QTLs skew the inferred distribution of expression QTLs detected using gene expression array data

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Dissecting the regulatory architecture of gene expression QTLs

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Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression

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seeQTL: a searchable database for human eQTLs

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Genomics of ADME gene expression: mapping expression quantitative trait loci relevant for absorption, distribution, metabolism and excretion of drugs in human liver

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Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses

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Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA

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The use of genome-wide eQTL associations in lymphoblastoid cell lines to identify novel genetic pathways involved in complex traits

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Gene expression in skin and lymphoblastoid cells: Refined statistical method reveals extensive overlap in cis-eQTL signals

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Candidate causal regulatory effects by integration of expression QTLs with complex trait genetic associations

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Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4512630

24 September 2018

Ghrelin can bind to a species of high density lipoprotein associated with paraoxonase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4512630

24 September 2018

A survey of genetic human cortical gene expression

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV194

21 January 2018

High-Dimensional Regression and Variable Selection Using CAR Scores

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV194

21 January 2018

Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/26019233

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the fatty acid binding site on glutathione S-transferase P

1 reference

https://pubmed.ncbi.nlm.nih.gov/26019233

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/HMG/DDV194

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26019233%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26019233%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26019233%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

ResearchGate publication ID

0 references

Sitelinks

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