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SARM1 activation triggers axon degeneration locally via NAD⁺ destruction
scientific article
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
4513950
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25908823%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
title
SARM1 activation triggers axon degeneration locally via NAD⁺ destruction
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
4513950
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25908823%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
main subject
Sterile alpha and TIR motif containing 1
1 reference
stated in
GOA release 2020-03-11
positive regulation of neuron death
1 reference
stated in
GOA release 2020-03-11
author
Jeffrey Milbrandt
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
4513950
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25908823%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
author name string
Josiah Gerdts
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
4513950
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25908823%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
E J Brace
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
4513950
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25908823%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
Yo Sasaki
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
4513950
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25908823%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
Aaron DiAntonio
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
4513950
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25908823%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
language of work or name
English
0 references
publication date
23 April 2015
1 reference
stated in
Europe PubMed Central
PMC publication ID
4513950
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25908823%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
published in
Science
1 reference
stated in
Europe PubMed Central
PMC publication ID
4513950
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25908823%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
volume
348
1 reference
stated in
Europe PubMed Central
PMC publication ID
4513950
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25908823%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
issue
6233
1 reference
stated in
Europe PubMed Central
PMC publication ID
4513950
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25908823%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
page(s)
453-457
1 reference
stated in
Europe PubMed Central
PMC publication ID
4513950
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25908823%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
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P7C3 neuroprotective chemicals function by activating the rate-limiting enzyme in NAD salvage
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PubMed Central
reference URL
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Mitochondrial dysfunction induces Sarm1-dependent cell death in sensory neurons
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Accurate measurement of nicotinamide adenine dinucleotide (NAD⁺) with high-performance liquid chromatography
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11 July 2018
Sarm1-mediated axon degeneration requires both SAM and TIR interactions
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PubMed Central
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Activation of the innate signaling molecule MAVS by bunyavirus infection upregulates the adaptor protein SARM1, leading to neuronal death
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T-cell death following immune activation is mediated by mitochondria-localized SARM.
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dSarm/Sarm1 is required for activation of an injury-induced axon death pathway
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Control of nonapoptotic developmental cell death in Caenorhabditis elegans by a polyglutamine-repeat protein
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11 July 2018
Image-based screening identifies novel roles for IkappaB kinase and glycogen synthase kinase 3 in axonal degeneration
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PubMed Central
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Pathways and subcellular compartmentation of NAD biosynthesis in human cells: from entry of extracellular precursors to mitochondrial NAD generation.
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11 July 2018
Axonal degeneration is blocked by nicotinamide mononucleotide adenylyltransferase (Nmnat) protein transduction into transected axons.
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Protein turnover of the Wallenda/DLK kinase regulates a retrograde response to axonal injury
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Nicotinamide mononucleotide adenylyl transferase-mediated axonal protection requires enzymatic activity but not increased levels of neuronal nicotinamide adenine dinucleotide
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11 July 2018
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11 July 2018
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based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1126/SCIENCE.1258366
1 reference
stated in
Europe PubMed Central
PMC publication ID
4513950
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25908823%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
ADS bibcode
2015Sci...348..453G
0 references
Fatcat ID
release_i6r6fymyufgoxeubutb5pr5rsu
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/i6r6fymyufgoxeubutb5pr5rsu
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PMC publication ID
4513950
1 reference
stated in
Europe PubMed Central
PMC publication ID
4513950
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25908823%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
PubMed publication ID
25908823
1 reference
stated in
Europe PubMed Central
PMC publication ID
4513950
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25908823%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 March 2020
ResearchGate publication ID
275345542
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