(Q35887221)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434908%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

Chromatin-targeting small molecules cause class-specific transcriptional changes in pancreatic endocrine cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434908%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434908%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

T.A. Lewis

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434908%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

15

Stuart L Schreiber

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434908%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

14

Paul A Clemons

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434908%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

13

Bridget K Wagner

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434908%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

author name string

Joshua C Gilbert

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434908%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Dina Fomina-Yadlin

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434908%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Alexander D Gitlin

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434908%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Yuan Yuan

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434908%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Florence F Wagner

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434908%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Edward B Holson

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434908%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Tuoping Luo

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434908%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Bradley Taylor

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434908%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Supriya Gupta

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434908%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Alykhan F Shamji

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434908%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

language of work or name

English

0 references

publication date

20 March 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434908%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

26 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434908%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

volume

109

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434908%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

issue

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434908%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

page(s)

5364-5369

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434908%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

26 January 2020

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/3325696

inferred from PubMed Central ID database lookup

cites work

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1 reference

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Discovery of histone deacetylase 8 selective inhibitors

11 July 2018

1 reference

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Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancers

11 July 2018

1 reference

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Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325696

Total synthesis of (+)-chaetocin and its analogues: their histone methyltransferase G9a inhibitory activity

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325696

Chemical phylogenetics of histone deacetylases

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325696

Romidepsin for the treatment of cutaneous T-cell lymphoma

11 July 2018

1 reference

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Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325696

The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325696

Targeting DNA methylation

11 July 2018

1 reference

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Histone deacetylase inhibitors: Potential in cancer therapy

11 July 2018

1 reference

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Cholesterol metabolism and pancreatic beta-cell function

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325696

Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325696

The anticancer agent chaetocin is a competitive substrate and inhibitor of thioredoxin reductase

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325696

Extreme makeover: converting one cell into another

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325696

Differential effects of class I isoform histone deacetylase depletion and enzymatic inhibition by belinostat or valproic acid in HeLa cells.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325696

Histone deacetylase inhibitors modify pancreatic cell fate determination and amplify endocrine progenitors

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325696

Histone deacetylase inhibitor panobinostat induces clinical responses with associated alterations in gene expression profiles in cutaneous T-cell lymphoma

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325696

Antitumor activity of histone deacetylase inhibitors in non-small cell lung cancer cells: development of a molecular predictive model

11 July 2018

1 reference

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Evolution of decitabine development: accomplishments, ongoing investigations, and future strategies

11 July 2018

1 reference

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Discovery and development of SAHA as an anticancer agent

11 July 2018

1 reference

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11 July 2018

The mammalian epigenome

1 reference

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Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase

11 July 2018

1 reference

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Coordinated recruitment of histone methyltransferase G9a and other chromatin-modifying enzymes in SHP-mediated regulation of hepatic bile acid metabolism

11 July 2018

1 reference

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The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325696

A series of novel, potent, and selective histone deacetylase inhibitors

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325696

Linear models and empirical bayes methods for assessing differential expression in microarray experiments

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325696

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325696

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325696

Identification and functional significance of genes regulated by structurally different histone deacetylase inhibitors

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325696

Functional role of G9a-induced histone methylation in small heterodimer partner-mediated transcriptional repression

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325696

Zebularine: a new drug for epigenetic therapy

11 July 2018

1 reference

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Small molecule regulators of protein arginine methyltransferases

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325696

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325696

Signaling network model of chromatin

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325696

Translating the Histone Code

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325696

Genomewide studies of histone deacetylase function in yeast

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325696

Analysis of a Chinese hamster ovary cell mutant with defective mobilization of cholesterol from the plasma membrane to the endoplasmic reticulum

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325696

Comparison of cytokine effects on mouse pancreatic alpha-cell and beta-cell lines. Viability, secretory function, and MHC antigen expression

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325696

Exploration of the internal cavity of histone deacetylase (HDAC) with selective HDAC1/HDAC2 inhibitors (SHI-1:2).

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325696

Identification of a specific inhibitor of the histone methyltransferase SU(VAR)3-9.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325696

Epigenetic reactivation of tumor suppressor genes by a novel small-molecule inhibitor of human DNA methyltransferases.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325696

Gene expression profiling of multiple histone deacetylase (HDAC) inhibitors: defining a common gene set produced by HDAC inhibition in T24 and MDA carcinoma cell lines

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325696

Direct Effect of Cholesterol on Insulin Secretion: A Novel Mechanism for Pancreatic -Cell Dysfunction

24 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22434908

12 December 2020

inferred from PubMed ID database lookup

Regulation of insulin secretion from beta-cell lines derived from transgenic mice insulinomas resembles that of normal beta-cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22434908

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.1201079109

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434908%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

0 references

release_fssu5heiqzdp5ho25qwzerhele

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/fssu5heiqzdp5ho25qwzerhele

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434908%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22434908%20AND%20SRC:MED&resulttype=core&format=json