(Q35888381)

English

A physiologically based pharmacokinetic model of mitoxantrone in mice and scale-up to humans: a semi-mechanistic model incorporating DNA and protein binding

scientific article published on 27 March 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

A physiologically based pharmacokinetic model of mitoxantrone in mice and scale-up to humans: a semi-mechanistic model incorporating DNA and protein binding (English)

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

pharmacokinetics

1 reference

based on heuristic

inferred from title

author name string

Guohua An

1

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Marilyn E Morris

2

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

language of work or name

0 references

publication date

27 March 2012

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

The AAPS Journal

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

14

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

2

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

352-364

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

ABC multidrug transporters: structure, function and role in chemoresistance.

1 reference

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11 July 2018

Role of the breast cancer resistance protein (ABCG2) in drug transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326165

11 July 2018

Mitoxantrone: a review of its use in multiple sclerosis

1 reference

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Doxorubicin pharmacokinetics: Macromolecule binding, metabolism, and excretion in the context of a physiologic model

1 reference

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11 July 2018

Comparative pharmacokinetic and cytotoxic analysis of three different formulations of mitoxantrone in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326165

11 July 2018

Topoisomerase II DNA cleavage stimulation, DNA binding activity, cytotoxicity, and physico-chemical properties of 2-aza- and 2-aza-oxide-anthracenedione derivatives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326165

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DNA-binding specificity and RNA polymerase inhibitory activity of bis(aminoalkyl)anthraquinones and bis(methylthio)vinylquinolinium iodides

1 reference

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Pharmacological disposition of 1,4-dihydroxy-5-8-bis[[2 [(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione dihydrochloride in the dog.

1 reference

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11 July 2018

Molecular and biochemical pharmacology of mitoxantrone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326165

11 July 2018

Physiologically Based Pharmacokinetic Modeling: Principles and Applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326165

11 July 2018

Mitoxantrone (novantrone): a review of experimental and early clinical studies

1 reference

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The structure and abundance of rat tissue cardiolipins

1 reference

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Methotrexate tissue distribution: prediction by a mathematical model

1 reference

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11 July 2018

High field 1H-NMR analysis of the 1:1 intercalation complex of the antitumor agent mitoxantrone and the DNA duplex [d(CpGpCpG)]

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326165

11 July 2018

Pharmacokinetics of mitoxantrone in man and laboratory animals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326165

11 July 2018

A clinical and pharmacokinetic study of mitoxantrone in acute nonlymphocytic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326165

11 July 2018

Relationship between the pharmacological activity of antitumor drugs Ametantrone and mitoxantrone (Novatrone) and their ability to condense nucleic acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326165

11 July 2018

Cisplatin pharmacokinetics: applications of a physiological model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326165

11 July 2018

Clinical assessment of the structure-activity relationship of anthracyclines and related synthetic derivatives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326165

11 July 2018

Pharmacokinetics and metabolism of mitoxantrone. A review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326165

11 July 2018

Physiologically based pharmacokinetic model for topotecan in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326165

24 September 2018

HPLC analysis of mitoxantrone in mouse plasma and tissues: application in a pharmacokinetic study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326165

24 September 2018

A physiologically based pharmacokinetic model of docetaxel disposition: from mouse to man.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326165

24 September 2018

Flavonoids are inhibitors of breast cancer resistance protein (ABCG2)-mediated transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326165

24 September 2018

Flow cytometric analysis of breast cancer resistance protein expression and function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3326165

24 September 2018

Evidence of a specific complex between adriamycin and negatively-charged phospholipids.

1 reference

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24 September 2018

Pharmacokinetic study on the mechanism of tissue distribution of doxorubicin: interorgan and interspecies variation of tissue-to-plasma partition coefficients in rats, rabbits, and guinea pigs.

1 reference

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24 September 2018

The effect of malignant effusions on methotrexate disposition

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451016

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methotrexate Pharmacokinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451016

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Experimental evidence of characteristic tissue distribution of adriamycin. Tissue DNA concentration as a determinant

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451016

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved high-performance liquid chromatography of the new antineoplastic agents bisantrene and mitoxantrone

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451016

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disposition of mitoxantrone in patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451016

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disposition of mitoxantrone in cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451016

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Excretion and metabolism of mitoxantrone in rabbits

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451016

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiological parameters in laboratory animals and humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451016

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Various inhibitors of DNA topoisomerases diminish repair-specific DNA incision in UV-irradiated human fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451016

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Body distribution of free, liposomal and nanoparticle-associated mitoxantrone in B16-melanoma-bearing mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451016

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic studies of mitoxantrone and one of its metabolites in serum and urine in patients with advanced breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22451016

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiologically based pharmacokinetics of cyclosporine A: extension to tissue distribution kinetics in rats and scale-up to human

1 reference

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inferred from PubMed ID database lookup

Identifiers

10.1208/S12248-012-9344-7

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

ResearchGate publication ID

0 references

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