(Q35891245)

English

Attenuation of TGF-β signaling suppresses premature senescence in a p21-dependent manner and promotes oncogenic Ras-mediated metastatic transformation in human mammary epithelial cells

scientific article published on 22 February 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Attenuation of TGF-β signaling suppresses premature senescence in a p21-dependent manner and promotes oncogenic Ras-mediated metastatic transformation in human mammary epithelial cells (English)

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Abhik Bandyopadhyay

4

object named as

Abhik Bandyopadhyay

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

8

object named as

Joseph Agyin

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

author name string

Shu Lin

1

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Junhua Yang

2

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Abdel G Elkahloun

3

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Long Wang

5

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

John E Cornell

6

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

I-Tien Yeh

7

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Gail Tomlinson

9

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Lu-Zhe Sun

10

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

publication date

22 February 2012

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Molecular Biology of the Cell

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

23

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

8

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

1569-1581

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization

1 reference

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Isolation and characterization of a metastatic hybrid cell line generated by ER negative and ER positive breast cancer cells in mouse bone marrow

1 reference

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11 July 2018

TGF-beta signaling engages an ATM-CHK2-p53-independent RAS-induced senescence and prevents malignant transformation in human mammary epithelial cells

1 reference

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SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression

1 reference

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Cancer statistics, 2010

1 reference

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A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis

1 reference

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11 July 2018

TGFbeta in Cancer

1 reference

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11 July 2018

Smads orchestrate specific histone modifications and chromatin remodeling to activate transcription

1 reference

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11 July 2018

Prognostic significance of basal-like phenotype and fascin expression in node-negative invasive breast carcinomas.

1 reference

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Smad4-expression is decreased in breast cancer tissues: a retrospective study

1 reference

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Phenotypic evaluation of the basal-like subtype of invasive breast carcinoma

1 reference

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Oncogenic pathway signatures in human cancers as a guide to targeted therapies

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11 July 2018

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

1 reference

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BRAFE600-associated senescence-like cell cycle arrest of human naevi

1 reference

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Tumour biology: senescence in premalignant tumours

1 reference

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Genes that mediate breast cancer metastasis to lung

1 reference

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DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

1 reference

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Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer

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Cell-type-specific responses to chemotherapeutics in breast cancer

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Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation

1 reference

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Synthesis and activity of new aryl- and heteroaryl-substituted pyrazole inhibitors of the transforming growth factor-beta type I receptor kinase domain

1 reference

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11 July 2018

The two faces of transforming growth factor beta in carcinogenesis

1 reference

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11 July 2018

Smad3 regulates senescence and malignant conversion in a mouse multistage skin carcinogenesis model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327327

11 July 2018

Links between tumor suppressors: p53 is required for TGF-beta gene responses by cooperating with Smads.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327327

11 July 2018

Oncogenic functions of tumour suppressor p21(Waf1/Cip1/Sdi1): association with cell senescence and tumour-promoting activities of stromal fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327327

11 July 2018

Gene expression profiling predicts clinical outcome of breast cancer

1 reference

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11 July 2018

A comparison of gene expression signatures from breast tumors and breast tissue derived cell lines

1 reference

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11 July 2018

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

1 reference

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11 July 2018

Binding of c-Myc to chromatin mediates mitogen-induced acetylation of histone H4 and gene activation.

1 reference

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11 July 2018

Responsiveness to transforming growth factor-beta (TGF-beta)-mediated growth inhibition is a function of membrane-bound TGF-beta type II receptor in human breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327327

11 July 2018

p16(MTS-1/CDKN2/INK4a) in cancer progression

1 reference

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11 July 2018

Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells.

1 reference

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11 July 2018

Molecular portraits of human breast tumours

1 reference

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11 July 2018

Defects in TGF-beta signaling overcome senescence of mouse keratinocytes expressing v-Ha-ras

1 reference

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11 July 2018

A soluble transforming growth factor beta type III receptor suppresses tumorigenicity and metastasis of human breast cancer MDA-MB-231 cells

1 reference

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11 July 2018

Murine fibroblasts lacking p21 undergo senescence and are resistant to transformation by oncogenic Ras.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327327

11 July 2018

c-Myc target genes involved in cell growth, apoptosis, and metabolism

1 reference

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11 July 2018

Expression of transforming growth factor beta type III receptor suppresses tumorigenicity of human breast cancer MDA-MB-231 cells

1 reference

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11 July 2018

Expression of a dominant-negative mutant TGF-beta type II receptor in transgenic mice reveals essential roles for TGF-beta in regulation of growth and differentiation in the exocrine pancreas

1 reference

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11 July 2018

Expression of a dominant-negative type II transforming growth factor beta (TGF-beta) receptor in the epidermis of transgenic mice blocks TGF-beta-mediated growth inhibition

1 reference

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11 July 2018

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

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The absence of p21Cip1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression.

1 reference

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TGF-beta-receptor-mediated signaling

1 reference

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11 July 2018

Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism

1 reference

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Signal transduction via serine/threonine kinase receptors

1 reference

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Differential regulation of p34cdc2 and p33cdk2 by transforming growth factor‐β1 in murine mammary epithelial cells

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Modulation of c-myc by transforming growth factor-beta in human colon carcinoma cells

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Selective inhibition of growth-related gene expression in murine keratinocytes by transforming growth factor beta

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TGF-beta 1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains.

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Interplay between the tumor suppressor p53 and TGF beta signaling shapes embryonic body axes in Xenopus

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Expression profile of agonistic Smads in human breast cancer cells: absence of regulation by estrogens.

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A kinase-defective transforming growth factor-beta receptor type II is a dominant-negative regulator for human breast carcinoma MCF-7 cells.

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Transgenic mice overexpressing a dominant-negative mutant type II transforming growth factor beta receptor show enhanced tumorigenesis in the mammary gland and lung in response to the carcinogen 7,12-dimethylbenz-[a]-anthracene

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24 September 2018

Transforming growth factor-beta and breast cancer risk in women with mammary epithelial hyperplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22357622

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autocrine TGFbeta supports growth and survival of human breast cancer MDA-MB-231 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22357622

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of growth factors, growth inhibiting factors, and their receptors in invasive breast cancer. I: An inventory in search of autocrine and paracrine loops

1 reference

https://pubmed.ncbi.nlm.nih.gov/22357622

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional Regulation of the p21(WAF1/CIP1)Gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/22357622

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TGF-beta and cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22357622

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1091/MBC.E11-10-0849

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

ResearchGate publication ID

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