(Q35906138)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187158%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

Human immunodeficiency virus-1 Tat activates NF-κB via physical interaction with IκB-α and p65 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187158%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187158%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Camillo Palmieri

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187158%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

author name string

Eleonora Vecchio

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187158%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Annamaria De Laurentiis

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187158%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Francesca Trimboli

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187158%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Antonio Pisano

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187158%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Cristina Falcone

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187158%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Marilena Pontoriero

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187158%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Annalisa Rossi

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187158%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Annarita Scialdone

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187158%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Francesca Fasanella Masci

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187158%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Giuseppe Scala

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187158%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Ileana Quinto

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187158%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

language of work or name

English

0 references

publication date

19 December 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187158%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

published in

Nucleic Acids Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187158%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

volume

40

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187158%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187158%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

page(s)

3548-3562

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187158%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial 3.0 Unported

19 January 2020

copyright license

start time

7 November 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3333881/fullTextXML

inferred from PubMed Central ID database lookup

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Microarray analysis of lymphatic tissue reveals stage-specific, gene expression signatures in HIV-1 infection

11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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Encoding NF-kappaB temporal control in response to TNF: distinct roles for the negative regulators IkappaBalpha and A20.

11 July 2018

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Human immunodeficiency virus type 1 Tat protein inhibits the SIRT1 deacetylase and induces T cell hyperactivation

11 July 2018

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HIV tat and neurotoxicity

11 July 2018

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Tat gets the "green" light on transcription initiation

11 July 2018

1 reference

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Cooperative interaction of C/EBP beta and Tat modulates MCP-1 gene transcription in astrocytes.

11 July 2018

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Inhibition of HIV-1 replication in primary human monocytes by the IkappaB-alphaS32/36A repressor of NF-kappaB

11 July 2018

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Recruitment of IkappaBalpha to the hes1 promoter is associated with transcriptional repression

11 July 2018

1 reference

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Oscillations in NF-kappaB signaling control the dynamics of gene expression

11 July 2018

1 reference

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De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

11 July 2018

1 reference

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Macrophage inflammatory protein-1

11 July 2018

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Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase

11 July 2018

1 reference

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Genetic analysis of NF- B/Rel transcription factors defines functional specificities

11 July 2018

1 reference

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Essential role of RelA Ser311 phosphorylation by zetaPKC in NF-kappaB transcriptional activation

11 July 2018

1 reference

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Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1)

11 July 2018

1 reference

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Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB.

11 July 2018

1 reference

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The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation

11 July 2018

1 reference

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Post-activation turn-off of NF-kappa B-dependent transcription is regulated by acetylation of p65

11 July 2018

1 reference

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NF-kappaB regulation in the immune system

11 July 2018

1 reference

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Physical and functional interaction of HIV-1 Tat with E2F-4, a transcriptional regulator of mammalian cell cycle

11 July 2018

1 reference

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NF-kappaB activation upon interaction of HIV-1 envelope glycoproteins with cell surface CD4 involves IkappaB kinases

11 July 2018

2 references

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11 July 2018

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Induction of rapid and extensive beta-chemokine synthesis in macrophages by human immunodeficiency virus type 1 and gp120, independently of their coreceptor phenotype

21 January 2018

1 reference

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Duration of nuclear NF-kappaB action regulated by reversible acetylation

11 July 2018

1 reference

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Regulation of human immunodeficiency virus type 1 infection, beta-chemokine production, and CCR5 expression in CD40L-stimulated macrophages: immune control of viral entry

11 July 2018

1 reference

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Simian immunodeficiency virus replicates to high levels in naturally infected African green monkeys without inducing immunologic or neurologic disease

11 July 2018

1 reference

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Hostile takeovers: viral appropriation of the NF-kB pathway

11 July 2018

1 reference

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Chemokine and chemokine-receptor expression in human glial elements: induction by the HIV protein, Tat, and chemokine autoregulation

11 July 2018

1 reference

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IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain

11 July 2018

1 reference

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HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter

11 July 2018

1 reference

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HIV-1 Tat protein mimicry of chemokines

11 July 2018

1 reference

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Interaction of human immunodeficiency virus type 1 Tat with the transcriptional coactivators p300 and CREB binding protein

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

Activation of integrated provirus requires histone acetyltransferase. p300 and P/CAF are coactivators for HIV-1 Tat

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

HIV-1 Tat induces the expression of the interleukin-6 (IL6) gene by binding to the IL6 leader RNA and by interacting with CAAT enhancer-binding protein beta (NF-IL6) transcription factors

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

The angiogenesis induced by HIV-1 tat protein is mediated by the Flk-1/KDR receptor on vascular endothelial cells.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

Chronic human immunodeficiency virus type 1 infection of myeloid cells disrupts the autoregulatory control of the NF-kappaB/Rel pathway via enhanced IkappaBalpha degradation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

Activation of transcription factor NF-kappaB by the Tat protein of human immunodeficiency virus type 1

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

Macrophage inflammatory protein-1alpha is induced by human immunodeficiency virus infection of monocyte-derived macrophages

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

Chemokines and T lymphocyte recruitment to lymph nodes in HIV infection.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

Human immunodeficiency virus type 1 infection alters chemokine beta peptide expression in human monocytes: implications for recruitment of leukocytes into brain and lymph nodes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

Regulation of NF-kappa B through the nuclear processing of p105 (NF-kappa B1) in Epstein-Barr virus-immortalized B cell lines.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

The p65 subunit of NF-kappa B regulates I kappa B by two distinct mechanisms

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

The human immunodeficiency virus type 1 Tat protein transactivates tumor necrosis factor beta gene expression through a TAR-like structure.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

Direct interaction of human TFIID with the HIV-1 transactivator tat

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

The expression of the interleukin 6 gene is induced by the human immunodeficiency virus 1 TAT protein

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

Lentivirus Tat proteins specifically associate with a cellular protein kinase, TAK, that hyperphosphorylates the carboxyl-terminal domain of the large subunit of RNA polymerase II: candidate for a Tat cofactor

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

Regulation of I kappa B alpha and p105 in monocytes and macrophages persistently infected with human immunodeficiency virus

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

In vitro and in vivo binding of human immunodeficiency virus type 1 Tat protein and Sp1 transcription factor

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

Tat trans-activates the human immunodeficiency virus through a nascent RNA target

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

Production of interleukins in human immunodeficiency virus-1-replicating lymph nodes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

Increased interleukin-6 production is associated with disease progression in HIV infection

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

Characterization of an immediate-early gene induced in adherent monocytes that encodes IκB-like activity

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

Functional roles for the TATA promoter and enhancers in basal and Tat-induced expression of the human immunodeficiency virus type 1 long terminal repeat

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

Specific NF-kappa B subunits act in concert with Tat to stimulate human immunodeficiency virus type 1 transcription

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

Transcriptional activation of the tumor necrosis factor alpha-inducible zinc finger protein, A20, is mediated by kappa B elements

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

Structural and functional insights into IκB-α/HIV-1 Tat interaction

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

Computational analysis and in vivo validation of a microRNA encoded by the IBTK gene, a regulator of B-lymphocytes differentiation and survival.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

Proteasome inhibitors block HIV-1 replication by affecting both cellular and viral targets.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

Divergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

Human T-cell lymphotropic virus type 1 tax induction of biologically Active NF-kappaB requires IkappaB kinase-1-mediated phosphorylation of RelA/p65.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

Lack of responsiveness of a nuclear factor-kappaB-regulated promoter to transactivation by human immunodeficiency virus 1 Tat in HeLa cells

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

The Tat protein of human immunodeficiency virus type-1 promotes vascular cell growth and locomotion by engaging the alpha5beta1 and alphavbeta3 integrins and by mobilizing sequestered basic fibroblast growth factor.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

Induction of interleukin-6 during human immunodeficiency virus infection.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3333881

Role of HIV-1 Tat and CC chemokine MIP-1alpha in the pathogenesis of HIV associated central nervous system disorders

24 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22187158

12 December 2020

inferred from PubMed ID database lookup

Activation of human microglial cells by HIV-1 gp41 and Tat proteins

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22187158

12 December 2020

inferred from PubMed ID database lookup

IkappaB-alpha represses the transcriptional activity of the HIV-1 Tat transactivator by promoting its nuclear export

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22187158

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1093/NAR/GKR1224

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187158%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187158%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

22187158

1 reference