(Q35908961)

11 August 2017

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title

Death effectors of beta-cell apoptosis in type 1 diabetes (English)

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11 August 2017

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Myung-Shik Lee

1

1 reference

PubMed ID

15464423

11 August 2017

Inik Chang

series ordinal

2

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PubMed ID

15464423

11 August 2017

Sunshin Kim

series ordinal

3

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11 August 2017

1 September 2004

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Molecular Genetics and Metabolism

11 August 2017

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11 August 2017

83

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11 August 2017

1-2

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11 August 2017

82-92

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Beta cell apoptosis in T cell-mediated autoimmune diabetes

11 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Apoptosis of pancreatic beta-cells detected in accelerated diabetes of NOD mice: no role of Fas-Fas ligand interaction in autoimmune diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

beta-cell glucotoxicity in the Psammomys obesus model of type 2 diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Lipotoxicity of beta-cells in obesity and in other causes of fatty acid spillover

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

The role of CD4+ and CD8+ T cells in the destruction of islet grafts by spontaneously diabetic mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

T helper cell subsets in insulin-dependent diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Participation of target Fas protein in apoptosis pathway induced by CD4+ Th1 and CD8+ cytotoxic T cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Lymphocyte-mediated cytotoxicity: two pathways and multiple effector molecules

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Development of insulitis without diabetes in transgenic mice lacking perforin-dependent cytotoxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

The role of Fas in autoimmune diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Requirement of Fas for the development of autoimmune diabetes in nonobese diabetic mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Mouse islet cell lysis mediated by interleukin-1-induced Fas.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Constitutive activation of the Fas ligand gene in mouse lymphoproliferative disorders.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Massive upregulation of the Fas ligand in lpr and gld mice: implications for Fas regulation and the graft-versus-host disease-like wasting syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Radiation and stress-induced apoptosis: a role for Fas/Fas ligand interactions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Mechanisms of beta cell death in diabetes: a minor role for CD95.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Inhibition of autoimmune diabetes by Fas ligand: the paradox is solved

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Significant role for Fas in the pathogenesis of autoimmune diabetes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Fas ligand in human serum

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Soluble Fas ligand-susceptible "memory" cells in mice but not in human: potential role of soluble Fas ligand in deletion of auto-reactive cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Fas is detectable on beta cells in accelerated, but not spontaneous, diabetes in nonobese diabetic mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Effective destruction of Fas-deficient insulin-producing beta cells in type 1 diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Fas/Fas ligand interactions play an essential role in the initiation of murine autoimmune diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

In vivo blockade of the Fas-Fas ligand pathway inhibits cyclophosphamide-induced diabetes in NOD mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Contribution of Fas to diabetes development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Perforin-independent beta-cell destruction by diabetogenic CD8(+) T lymphocytes in transgenic nonobese diabetic mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Fas is expressed in murine pancreatic islet cells and an insulinoma cell line but does not mediate their apoptosis in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

IL-1 receptor deficiency slows progression to diabetes in the NOD mouse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

IFN-gamma/TNF-alpha synergism as the final effector in autoimmune diabetes: a key role for STAT1/IFN regulatory factor-1 pathway in pancreatic beta cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Defective TNF-alpha-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Transmembrane TNF and IFNgamma induce caspase-independent death of primary mouse pancreatic beta cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Prevention of diabetes in nonobese diabetic mice by tumor necrosis factor (TNF): similarities between TNF-alpha and interleukin 1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Effect of tumor necrosis factor alpha on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

HLA class II induction in human islet cells by interferon-γ plus tumour necrosis factor or lymphotoxin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

IFN gamma/TNF alpha synergism in MHC class II induction: effect of nicotinamide on MHC class II expression but not on islet-cell apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Diabetes and tolerance in transgenic mice expressing class II MHC molecules in pancreatic beta cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Nitric oxide-induced apoptosis in pancreatic beta cells is mediated by the endoplasmic reticulum stress pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Does nitric oxide mediate autoimmune destruction of beta-cells? Possible therapeutic interventions in IDDM

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Caspase-1 is not required for type 1 diabetes in the NOD mouse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Suppression of TNF-alpha-induced apoptosis by NF-kappaB

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

In utero gene therapy: the case for.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Hydrogen peroxide-induced apoptosis is CD95-independent, requires the release of mitochondria-derived reactive oxygen species and the activation of NF-kappaB.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Inhibition of cytokine-induced NF-kappaB activation by adenovirus-mediated expression of a NF-kappaB super-repressor prevents beta-cell apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Protection of human islets from the effects of interleukin-1beta by adenoviral gene transfer of an Ikappa B repressor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Synergistic activation of NF-kappab and inducible isoform of nitric oxide synthase induction by interferon-gamma and tumor necrosis factor-alpha in INS-1 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Selection of insulinoma cell lines with resistance to interleukin-1beta- and gamma-interferon-induced cytotoxicity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Tissue inhibitor of metalloproteinase-1 prevents cytokine-mediated dysfunction and cytotoxicity in pancreatic islets and beta-cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Active repression of antiapoptotic gene expression by RelA(p65) NF-kappa B.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

IL-1 produced and released endogenously within human islets inhibits beta cell function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Nuclear Factor κB Protects Pancreatic β-Cells From Tumor Necrosis Factor-α-Mediated Apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Mutational analysis of the double-stranded RNA (dsRNA) binding domain of the dsRNA-activated protein kinase, PKR.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Glutamate neurotoxicity in cortical cell culture is calcium dependent

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

The mitochondrial permeability transition pore and its role in cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Increased activity of L-type Ca2+ channels exposed to serum from patients with type I diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

The mitochondrial permeability transition.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Mitochondrial control of apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Role of calcium in pancreatic islet cell death by IFN-gamma/TNF-alpha

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

RyR2 and calpain-10 delineate a novel apoptosis pathway in pancreatic islets

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMGME.2004.08.002

10.1016/J.YMGME.2004.08.002

7 January 2021

Identifiers

DOI

1 reference

11 August 2017

1 reference

PubMed ID

15464423