(Q36380639)

13 August 2017

Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice (English)

1 reference

13 August 2017

4

Zinkernagel RM

1 reference

13 August 2017

Kägi D

1

1 reference

13 August 2017

Odermatt B

2

1 reference

13 August 2017

Seiler P

3

1 reference

13 August 2017

Mak TW

5

1 reference

13 August 2017

Hengartner H

6

1 reference

13 August 2017

language of work or name

English

0 references

publication date

1 October 1997

1 reference

Journal of Experimental Medicine

13 August 2017

1 reference

13 August 2017

186

1 reference

13 August 2017

989-997

1 reference

13 August 2017

7

1 reference

Interferon-gamma is essential for destruction of beta cells and development of insulin-dependent diabetes mellitus

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199062

Development of insulitis without diabetes in transgenic mice lacking perforin-dependent cytotoxicity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199062

CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199062

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199062

Effect of tumor necrosis factor alpha on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199062

A null mutation in the perforin gene impairs cytolytic T lymphocyte- and natural killer cell-mediated cytotoxicity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199062

Genetic control of autoimmune diabetes in the NOD mouse

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199062

Immune function in mice lacking the perforin gene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199062

Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199062

Breeding of a non-obese, diabetic strain of mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199062

Syngeneic transfer of autoimmune diabetes from diabetic NOD mice to healthy neonates. Requirement for both L3T4+ and Lyt-2+ T cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199062

Genomic organization of the mouse pore-forming protein (perforin) gene and localization to chromosome 10. Similarities to and differences from C9.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199062

Does nitric oxide mediate autoimmune destruction of beta-cells? Possible therapeutic interventions in IDDM

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199062

Constitutive and induced expression of APO-1, a new member of the nerve growth factor/tumor necrosis factor receptor superfamily, in normal and neoplastic cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199062

Detection of perforin and granzyme A mRNA in infiltrating cells during infection of mice with lymphocytic choriomeningitis virus

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199062

In vivo expression of perforin by CD8+ lymphocytes in autoimmune disease. Studies on spontaneous and adoptively transferred diabetes in nonobese diabetic mice

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199062

Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199062

Genetic analysis of autoimmune type 1 diabetes mellitus in mice

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199062

Kinetics of response in lymphoid tissues to antiretroviral therapy of HIV-1 infection

28 June 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.186.7.989

Genetic absence of gamma-interferon delays but does not prevent diabetes in NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.186.7.989

Two distinct pathways of specific killing revealed by perforin mutant cytotoxic T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.186.7.989

Therapy with monoclonal antibodies by elimination of T-cell subsets in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.186.7.989

CD8 T cells are not required for islet destruction induced by a CD4+ islet-specific T-cell clone

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.186.7.989

T helper cell subsets in insulin-dependent diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.186.7.989

In situ characterization of autoimmune phenomena and expression of HLA molecules in the pancreas in diabetic insulitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.186.7.989

Major histocompatibility complex class I molecules are required for the development of insulitis in non-obese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.186.7.989

Beta 2-microglobulin-deficient NOD mice do not develop insulitis or diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.186.7.989

Prevention of insulitis and diabetes in beta 2-microglobulin-deficient non-obese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.186.7.989

Major histocompatibility complex class I-deficient NOD-B2mnull mice are diabetes and insulitis resistant

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.186.7.989

The role of CD8+ T cells in the initiation of insulin-dependent diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.186.7.989

The effect of cyclophosphamide treatment on lymphocyte subsets in the nonobese diabetic mouse: a comparison of various lymphoid organs

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.186.7.989

Progression from insulitis to beta-cell destruction in NOD mouse requires L3T4+ T-lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.186.7.989

Administration of silica particles or anti-Lyt2 antibody prevents beta-cell destruction in NOD mice given cyclophosphamide

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.186.7.989

The role of Fas in autoimmune diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.186.7.989

Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.186.7.989

Human tumor necrosis factor potentiates human interleukin 1-mediated rat pancreatic beta-cell cytotoxicity

21 January 2018

1 reference

12 December 2020

Expression of apoptosis-inducing CD95 (Fas/Apo-1) on human beta-cells sorted by flow-cytometry and cultured in vitro

1 reference

12 December 2020

Potential involvement of Fas and its ligand in the pathogenesis of Hashimoto's thyroiditis

1 reference

12 December 2020

Both the Lyt-2+ and L3T4+ T cell subsets are required for the transfer of diabetes in nonobese diabetic mice

1 reference

12 December 2020

IFN-gamma and tumor necrosis factor-alpha. Cytotoxicity to murine islets of Langerhans

1 reference

12 December 2020

Promotion of spontaneous diabetes in non-obese diabetes-prone mice by cyclophosphamide

1 reference

12 December 2020

Flow cytometric enumeration of mononuclear cell populations infiltrating the islets of Langerhans in prediabetic NOD mice: development of a model of autoimmune insulitis for type I diabetes

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.186.7.989

1 reference

13 August 2017

1 reference

13 August 2017

1 reference