(Q35911112)

11 August 2017

1 reference

title

Role of oxidative stress and inflammation in the origin of Type 2 diabetes--a paradigm shift (English)

1 reference

11 August 2017

1 reference

1 reference

Sivaram Pillarisetti

1

1 reference

PubMed ID

15469391

11 August 2017

Uday Saxena

series ordinal

2

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PubMed ID

15469391

11 August 2017

language of work or name

English

0 references

publication date

1 October 2004

1 reference

Expert Opinion on Therapeutic Targets

11 August 2017

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11 August 2017

8

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11 August 2017

5

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11 August 2017

401-408

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Lifetime Risk for Diabetes Mellitus in the United States

11 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

Insulin Resistant States and Insulin Signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

Intrinsic and extrinsic uncoupling of oxidative phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

The impact of fatty acid oxidation on energy utilization: targets and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

Mitochondrial dysfunction in the elderly: possible role in insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

Superoxide-mediated activation of uncoupling protein 2 causes pancreatic beta cell dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

Uncoupling protein 2: a possible link between fatty acid excess and impaired glucose-induced insulin secretion?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

Antioxidant and prooxidant mechanisms in the regulation of redox(y)-sensitive transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

Aspirin inhibits serine phosphorylation of insulin receptor substrate 1 in tumor necrosis factor-treated cells through targeting multiple serine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

Inflammation: the link between insulin resistance, obesity and diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

A central role for JNK in obesity and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

Interleukin-6 induces oxidative stress and endothelial dysfunction by overexpression of the angiotensin II type 1 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

Dietary antioxidant intake and risk of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

Dietary factors determining diabetes and impaired glucose tolerance. A 20-year follow-up of the Finnish and Dutch cohorts of the Seven Countries Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

Vitamin C and hyperglycemia in the European Prospective Investigation into Cancer--Norfolk (EPIC-Norfolk) study: a population-based study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

Did the antioxidant trials fail to validate the oxidation hypothesis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

Is oxidative stress the pathogenic mechanism underlying insulin resistance, diabetes, and cardiovascular disease? The common soil hypothesis revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

NOX enzymes and the biology of reactive oxygen

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

Evidence for contribution of vascular NAD(P)H oxidase to increased oxidative stress in animal models of diabetes and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

Essential role of the NADPH oxidase subunit p47(phox) in endothelial cell superoxide production in response to phorbol ester and tumor necrosis factor-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

A possible target of antioxidative therapy for diabetic vascular complications-vascular NAD(P)H oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

Azelnidipine, a newly developed long-acting calcium antagonist, inhibits tumor necrosis factor-alpha-induced interleukin-8 expression in endothelial cells through its anti-oxidative properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

6,6'-Bis(2-hydroxyphenyl)-2,2'-bipyridine manganese(III) complexes: a novel series of superoxide dismutase and catalase mimetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

Reversal of age-related learning deficits and brain oxidative stress in mice with superoxide dismutase/catalase mimetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

Alpha-lipoic acid: a multifunctional antioxidant that improves insulin sensitivity in patients with type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

Oral administration of RAC-alpha-lipoic acid modulates insulin sensitivity in patients with type-2 diabetes mellitus: a placebo-controlled pilot trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

Effects of an engineered human anti-TNF-alpha antibody (CDP571) on insulin sensitivity and glycemic control in patients with NIDDM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

Are oxidative stress-activated signaling pathways mediators of insulin resistance and beta-cell dysfunction?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

Consequences on beta-cell function and reserve after long-term pancreas transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.5.401

21 January 2018

Identifiers

DOI

10.1517/14728222.8.5.401

1 reference

11 August 2017

1 reference

PubMed ID

15469391