(Q35911472)

English

Raf and VEGF: emerging therapeutic targets in Kaposi's sarcoma-associated herpesvirus infection and angiogenesis in hematopoietic and nonhematopoietic tumors

scientific article published in January 2005

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

1 reference

Europe PubMed Central

Raf and VEGF: emerging therapeutic targets in Kaposi's sarcoma-associated herpesvirus infection and angiogenesis in hematopoietic and nonhematopoietic tumors (English)

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

author name string

Hamden KE

1

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

Whitman AG

2

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

Ford PW

3

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

Shelton JG

4

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

McCubrey JA

5

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

Akula SM

6

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

publication date

1 January 2005

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

19

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

18-26

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

https://scigraph.springernature.com/pub.10.1038/sj.leu.2403532

0 references

Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma

1 reference

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Molecular biology and pathogenesis of Kaposi sarcoma-associated herpesvirus

1 reference

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21 January 2018

Spectrum of Kaposi's sarcoma-associated herpesvirus, or human herpesvirus 8, diseases

1 reference

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21 January 2018

Biology of Kaposi's sarcoma

1 reference

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21 January 2018

Micronodular Kaposi's sarcoma - a new variant of classic-sporadic Kaposi's sarcoma

1 reference

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21 January 2018

KSHV/HHV8-associated lymphoproliferations in the AIDS setting

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21 January 2018

Cytokine-mediated growth promotion of Kaposi's sarcoma and primary effusion lymphoma.

1 reference

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21 January 2018

Kaposi's sarcoma and other manifestations of human herpesvirus 8.

1 reference

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21 January 2018

Update on Kaposi's sarcoma and other HHV8 associated diseases. Part 2: pathogenesis, Castleman's disease, and pleural effusion lymphoma

1 reference

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21 January 2018

Viral G protein-coupled receptor and Kaposi's sarcoma: a model of paracrine neoplasia?

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21 January 2018

Human herpes virus 8 interleukin-6 homologue triggers gp130 on neuronal and hematopoietic cells

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The N-terminal propiece of interleukin 1 alpha is a transforming nuclear oncoprotein

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Signaling via the interferon-alpha receptor in chronic myelogenous leukemia cells

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Inflammatory cytokines and the reactivation of Kaposi's sarcoma-associated herpesvirus lytic replication

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Lessons from 10 years of interferon beta-1b (Betaferon/Betaseron) treatment

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Regulation of interferon-gamma gene expression

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Multiple roles for tumor necrosis factor-alpha and lymphotoxin alpha/beta in immunity and autoimmunity

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Autocrine lymphotoxin production in Epstein-Barr virus-immortalized B cells: induction via NF-kappaB activation mediated by EBV-derived latent membrane protein 1.

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21 January 2018

What is transforming growth factor-beta (TGF-beta)?

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Transforming growth factor-beta signaling in normal and malignant hematopoiesis

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Vascular endothelial growth factor/vascular permeability factor in the pathogenesis of primary effusion lymphomas

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Human herpesvirus-8-transformed endothelial cells have functionally activated vascular endothelial growth factor/vascular endothelial growth factor receptor

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Biosynthesis and processing by phorbol ester of the cells surface-associated precursor form of heparin-binding EGF-like growth factor.

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The membrane protein CD9/DRAP 27 potentiates the juxtacrine growth factor activity of the membrane-anchored heparin-binding EGF-like growth factor

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The ErbB signaling network: receptor heterodimerization in development and cancer

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GM-CSF in inflammation and autoimmunity.

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Structure and function of placental growth factor

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Scatter factor/hepatocyte growth factor (SF/HGF) content and function in human gliomas

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Role of scatter factor in the pathogenesis of AIDS-related Kaposi sarcoma.

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Platelet-derived growth factor receptors: a therapeutic target in solid tumors

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Oncostatin M, a multifunctional cytokine

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Induction of HHV-8 lytic cycle replication by inflammatory cytokines produced by HIV-1-infected T cells

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The role of epidermal growth factor and its receptors in mammalian CNS.

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EGF Receptor Signaling: Putting a New Spin on Eye Development

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G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator

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Differential effects of kinase cascade inhibitors on neoplastic and cytokine-mediated cell proliferation

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Differential abilities of activated Raf oncoproteins to abrogate cytokine dependency, prevent apoptosis and induce autocrine growth factor synthesis in human hematopoietic cells

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Effects of inducible MEK1 activation on the cytokine dependency of lymphoid cells

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The Raf/MEK/ERK pathway: new concepts of activation.

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Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus

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Mutations of the BRAF gene in human cancer

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V599EB-RAF is an oncogene in melanocytes

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Conferring specificity on the ubiquitous Raf/MEK signalling pathway

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A JC virus-induced signal is required for infection of glial cells by a clathrin- and eps15-dependent pathway

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Epidermal growth factor receptor is a cellular receptor for human cytomegalovirus

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Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 envelope glycoprotein gB induces the integrin-dependent focal adhesion kinase-Src-phosphatidylinositol 3-kinase-rho GTPase signal pathways and cytoskeletal rearrangements

1 reference

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Raf promotes human herpesvirus-8 (HHV-8/KSHV) infection.

1 reference

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Differential abilities of the Raf family of protein kinases to abrogate cytokine dependency and prevent apoptosis in murine hematopoietic cells by a MEK1-dependent mechanism

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Vascular endothelial growth factor augments human herpesvirus-8 (HHV-8/KSHV) infection.

1 reference

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VEGF-receptor signal transduction

1 reference

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The CD40-induced signaling pathway in endothelial cells resulting in the overexpression of vascular endothelial growth factor involves Ras and phosphatidylinositol 3-kinase.

1 reference

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Growing and shaping the vascular tree: multiple roles for VEGF

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Expression of VEGF isoforms by epiphyseal chondrocytes during low-oxygen tension is HIF-1 alpha dependent.

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Autocrine signaling in carcinoma: VEGF and the alpha6beta4 integrin

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Vascular endothelial growth factor as a target for anticancer therapy

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Oncogenes and angiogenesis: signaling three-dimensional tumor growth

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Novel 4-anilinoquinazolines with C-7 basic side chains: design and structure activity relationship of a series of potent, orally active, VEGF receptor tyrosine kinase inhibitors

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New anilinophthalazines as potent and orally well absorbed inhibitors of the VEGF receptor tyrosine kinases useful as antagonists of tumor-driven angiogenesis.

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Design and discovery of small molecules targeting raf-1 kinase

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Peptidoglycan induces nuclear factor-kappaB activation and cyclooxygenase-2 expression via Ras, Raf-1, and ERK in RAW 264.7 macrophages

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CI-1040 (PD184352), a targeted signal transduction inhibitor of MEK (MAPKK)

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Use of mitogenic cascade blockers for treatment of C-Raf induced lung adenoma in vivo: CI-1040 strongly reduces growth and improves lung structure

1 reference

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Selective expression of stromal-derived factor-1 in the capillary vascular endothelium plays a role in Kaposi sarcoma pathogenesis

1 reference

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7 January 2021

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Regulation of endothelial cell branching morphogenesis by endogenous chemokine stromal-derived factor-1

1 reference

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7 January 2021

based on heuristic

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Interleukin-1 beta increases the BCL-2/BAX ratio in Kaposi's sarcoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403532

7 January 2021

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1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403532

7 January 2021

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Interleukin 8 (IL-8) and the release of leukocytes from the bone marrow

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403532

7 January 2021

based on heuristic

inferred from DOI database lookup

Oncostatin M: foe or friend?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403532

7 January 2021

based on heuristic

inferred from DOI database lookup

All three receptors for vascular endothelial growth factor (VEGF) are expressed on B-chronic lymphocytic leukemia (CLL) cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403532

7 January 2021

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inferred from DOI database lookup

Inhibition of vascular endothelial growth factor in the treatment of colorectal cancer

1 reference

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7 January 2021

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Discovery of 5-[5-fluoro-2-oxo-1,2- dihydroindol-(3Z)-ylidenemethyl]-2,4- dimethyl-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)amide, a novel tyrosine kinase inhibitor targeting vascular endothelial and platelet-derived growth factor receptor

1 reference

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7 January 2021

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Effect of SB 203580 on the activity of c-Raf in vitro and in vivo

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Inefficient establishment of KSHV latency suggests an additional role for continued lytic replication in Kaposi sarcoma pathogenesis.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Human herpesvirus 8 DNA sequences in CD8+ T cells

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.LEU.2403532

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

ResearchGate publication ID

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