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Tumor suppressor function of RUNX3 in breast cancer
scientific article published in May 2012
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scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
3337355
retrieved
11 August 2017
title
Tumor suppressor function of RUNX3 in breast cancer
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3337355
retrieved
11 August 2017
main subject
breast cancer
1 reference
based on heuristic
inferred from title
author name string
Lin-Feng Chen
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
3337355
retrieved
11 August 2017
publication date
1 May 2012
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stated in
Europe PubMed Central
PMCID
3337355
retrieved
11 August 2017
published in
Journal of Cellular Biochemistry
1 reference
stated in
Europe PubMed Central
PMCID
3337355
retrieved
11 August 2017
volume
113
1 reference
stated in
Europe PubMed Central
PMCID
3337355
retrieved
11 August 2017
issue
5
1 reference
stated in
Europe PubMed Central
PMCID
3337355
retrieved
11 August 2017
page(s)
1470-1477
1 reference
stated in
Europe PubMed Central
PMCID
3337355
retrieved
11 August 2017
cites work
RUNX3 acts as a tumor suppressor in breast cancer by targeting estrogen receptor α
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PubMed Central
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27 July 2018
TGF-β signaling in breast cancer cell invasion and bone metastasis
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27 July 2018
Lysine methyltransferase G9a is required for de novo DNA methylation and the establishment, but not the maintenance, of proviral silencing
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PubMed Central
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27 July 2018
Global cancer statistics
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PubMed Central
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27 July 2018
Control of RUNX3 by histone methyltransferases
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PubMed Central
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27 July 2018
Role of Notch and its oncogenic signaling crosstalk in breast cancer
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Cancer statistics, 2010
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RUNX3 is multifunctional in carcinogenesis of multiple solid tumors
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PubMed Central
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Src kinase phosphorylates RUNX3 at tyrosine residues and localizes the protein in the cytoplasm
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PubMed Central
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Runt-related transcription factor RUNX3 is a target of MDM2-mediated ubiquitination
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Molecular pathology of RUNX3 in human carcinogenesis
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Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer
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27 July 2018
Hypoxic silencing of tumor suppressor RUNX3 by histone modification in gastric cancer cells
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337355
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27 July 2018
RUNX3 attenuates beta-catenin/T cell factors in intestinal tumorigenesis
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Regulation of Estrogen Receptor α by the SET7 Lysine Methyltransferase
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Stromal gene expression predicts clinical outcome in breast cancer
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27 July 2018
Enhancer of zeste homologue 2 (EZH2) down-regulates RUNX3 by increasing histone H3 methylation
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PubMed Central
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27 July 2018
Estrogen receptor-alpha hinge-region lysines 302 and 303 regulate receptor degradation by the proteasome
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27 July 2018
Epithelial progeny of estrogen-exposed breast progenitor cells display a cancer-like methylome
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27 July 2018
RUNX3 inactivation by frequent promoter hypermethylation and protein mislocalization constitute an early event in breast cancer progression.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337355
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27 July 2018
Downregulation of the RUNX3 gene by promoter hypermethylation and hemizygous deletion in breast cancer
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Potential advantages of DNA methyltransferase 1 (DNMT1)-targeted inhibition for cancer therapy
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Estrogen carcinogenesis in breast cancer
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27 July 2018
RUNX3 cooperates with FoxO3a to induce apoptosis in gastric cancer cells
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Phosphorylation, acetylation and ubiquitination: the molecular basis of RUNX regulation
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27 July 2018
CHIP (carboxyl terminus of Hsc70-interacting protein) promotes basal and geldanamycin-induced degradation of estrogen receptor-alpha
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27 July 2018
Wnt signalling in stem cells and cancer
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27 July 2018
Ligand-dependent switching of ubiquitin-proteasome pathways for estrogen receptor
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27 July 2018
Inhibiting proteasomal proteolysis sustains estrogen receptor-alpha activation.
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27 July 2018
Oncogenic potential of the RUNX gene family: 'overview'.
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27 July 2018
Transforming growth factor-beta stimulates p300-dependent RUNX3 acetylation, which inhibits ubiquitination-mediated degradation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337355
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Methylation of RUNX3 in various types of human cancers and premalignant stages of gastric carcinoma
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RUNX transcription factors as key targets of TGF-beta superfamily signaling
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27 July 2018
Runx3 controls the axonal projection of proprioceptive dorsal root ganglion neurons
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Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylation
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The leukemic protein core binding factor beta (CBFbeta)-smooth-muscle myosin heavy chain sequesters CBFalpha2 into cytoskeletal filaments and aggregates
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Multistep carcinogenesis of breast cancer and tumour heterogeneity
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Nucleocytoplasmic transport: signals, mechanisms and regulation
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RUNX3 in oncogenic and anti-oncogenic signaling in gastrointestinal cancers.
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Epithelial-mesenchymal transition and cancer stem cells: a dangerously dynamic duo in breast cancer progression
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24 September 2018
RUNX3 directly interacts with intracellular domain of Notch1 and suppresses Notch signaling in hepatocellular carcinoma cells
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24 September 2018
Jab1/CSN5 induces the cytoplasmic localization and degradation of RUNX3.
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24 September 2018
Pim-1 kinase phosphorylates and stabilizes RUNX3 and alters its subcellular localization.
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24 September 2018
Expression of RUNX3 gene, methylation status and clinicopathological significance in breast cancer and breast cancer cell lines
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24 September 2018
Signaling by estrogens
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The epigenomics of cancer
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24 September 2018
Targets of genome copy number reduction in primary breast cancers identified by integrative genomics
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24 September 2018
RUNX3 is frequently inactivated by dual mechanisms of protein mislocalization and promoter hypermethylation in breast cancer
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3337355
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24 September 2018
The RUNX3 tumor suppressor upregulates Bim in gastric epithelial cells undergoing transforming growth factor beta-induced apoptosis
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24 September 2018
DNA methylation-associated inactivation of TGFbeta-related genes DRM/Gremlin, RUNX3, and HPP1 in human cancers
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24 September 2018
RUNX3, a novel tumor suppressor, is frequently inactivated in gastric cancer by protein mislocalization.
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Oncogenes and tumor suppressor genes in breast cancer: potential diagnostic and therapeutic applications
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Regulation of tumor suppressors by nuclear-cytoplasmic shuttling
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Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development.
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Inhibition of growth of mouse gastric cancer cells by Runx3, a novel tumor suppressor
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24 September 2018
The Runx3 transcription factor regulates development and survival of TrkC dorsal root ganglia neurons
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Worms gang up on bacteria
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Estrogen receptor transcription and transactivation: Estrogen receptor alpha and estrogen receptor beta: regulation by selective estrogen receptor modulators and importance in breast cancer
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Detection of promoter hypermethylation in serum samples of cancer patients by methylation-specific polymerase chain reaction for tumour suppressor genes including RUNX3
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The fundamental role of epigenetic events in cancer
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12 December 2020
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Identifiers
DOI
10.1002/JCB.24074
1 reference
stated in
Europe PubMed Central
PMCID
3337355
retrieved
11 August 2017
PMCID
3337355
1 reference
stated in
Europe PubMed Central
PMCID
3337355
retrieved
11 August 2017
PubMed ID
22275124
1 reference
stated in
Europe PubMed Central
PMCID
3337355
retrieved
11 August 2017
ResearchGate publication ID
221775354
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