(Q35921144)

English

Differential phosphorylation of vertebrate p34cdc2 kinase at the G1/S and G2/M transitions of the cell cycle: identification of major phosphorylation sites

scientific article published on February 1, 1991

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scholarly article

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Europe PubMed Central

11 August 2017

Differential phosphorylation of vertebrate p34cdc2 kinase at the G1/S and G2/M transitions of the cell cycle: identification of major phosphorylation sites (English)

1 reference

Europe PubMed Central

11 August 2017

phosphorylation

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based on heuristic

inferred from title

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8 December 2022

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E. A. Nigg

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8 December 2022

author name string

W. Krek

1

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publication date

1 February 1991

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full work available at URL

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1846803/?tool=EBI

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8 December 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1846803/pdf/?tool=EBI

Portable Document Format

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8 December 2022

https://europepmc.org/articles/PMC452647

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8 December 2022

https://europepmc.org/articles/PMC452647?pdf=render

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1846803

8 December 2022

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fj.1460-2075.1991.tb07951.x

1 reference

10.1002/J.1460-2075.1991.TB07951.X

https://api.crossref.org/works/10.1002/J.1460-2075.1991.TB07951.X

8 December 2022

http://onlinelibrary.wiley.com/wol1/doi/10.1002/j.1460-2075.1991.tb07951.x/fullpdf

1 reference

10.1002/J.1460-2075.1991.TB07951.X

https://api.crossref.org/works/10.1002/J.1460-2075.1991.TB07951.X

8 December 2022

The EMBO Journal

1 reference

Europe PubMed Central

11 August 2017

10

1 reference

Europe PubMed Central

11 August 2017

305-316

1 reference

Europe PubMed Central

11 August 2017

2

1 reference

Europe PubMed Central

11 August 2017

Cyclin synthesis, modification and destruction during meiotic maturation of the starfish oocyte

1 reference

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Isolation of monoclonal antibodies that recognize the transforming proteins of avian sarcoma viruses

1 reference

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2 October 2017

Complete amino acid sequence of the catalytic subunit of bovine cardiac muscle cyclic AMP-dependent protein kinase

1 reference

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2 October 2017

Detection and quantification of phosphotyrosine in proteins

1 reference

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2 October 2017

Cyclin: a protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division

1 reference

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2 October 2017

Genetic control of the cell division cycle in yeast

1 reference

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2 October 2017

Site-specific mutagenesis of cdc2+, a cell cycle control gene of the fission yeast Schizosaccharomyces pombe

1 reference

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2 October 2017

Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes

1 reference

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2 October 2017

Cell cycle regulation in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

p13suc1 acts in the fission yeast cell division cycle as a component of the p34cdc2 protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

Molecular cloning of cDNAs encoding two isoforms of the catalytic subunit of protein phosphatase 2A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

Molecular cloning and characterization of the mRNA for cyclin from sea urchin eggs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

Structure and developmental expression of the chicken CDC2 kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

Dominoes and clocks: the union of two views of the cell cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

Mitotic control by metaphase-promoting factor and cdc proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

The Saccharomyces cerevisiae CKS1 gene, a homolog of the Schizosaccharomyces pombe suc1+ gene, encodes a subunit of the Cdc28 protein kinase complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

Maturation promoting factor, cyclin and the control of M-phase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

Involvement of protein phosphatases 1 and 2A in the control of M phase-promoting factor activity in starfish

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

An essential G1 function for cyclin-like proteins in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

Simple and complex cell cycles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

Isolation of a human cyclin cDNA: evidence for cyclin mRNA and protein regulation in the cell cycle and for interaction with p34cdc2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

A family of cyclin homologs that control the G1 phase in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

The role of cyclin synthesis and degradation in the control of maturation promoting factor activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

Cyclin synthesis drives the early embryonic cell cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

Expression and function of Drosophila cyclin A during embryonic cell cycle progression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

Cyclin is a component of the sea urchin egg M-phase specific histone H1 kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

The role of cyclin synthesis, modification and destruction in the control of cell division.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

MPF from starfish oocytes at first meiotic metaphase is a heterodimer containing one molecule of cdc2 and one molecule of cyclin B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

The role of cyclin B in meiosis I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

Enforced expression of the c-myc oncogene inhibits cell differentiation by precluding entry into a distinct predifferentiation state in G0/G1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

Protein kinase recognition sequence motifs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

Human cDNAs encoding homologs of the small p34Cdc28/Cdc2-associated protein of Saccharomyces cerevisiae and Schizosaccharomyces pombe

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

Controls of cell proliferation in yeast and animals.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

In vitro disassembly of the nuclear lamina and M phase-specific phosphorylation of lamins by cdc2 kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

Mitotic role for the Cdc28 protein kinase of Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

Cdc2 H1 kinase is negatively regulated by a type 2A phosphatase in the Xenopus early embryonic cell cycle: evidence from the effects of okadaic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

p34cdc2: the S and M kinase?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

Cell cycle control in eukaryotes: molecular mechanisms of cdc2 activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

The A- and B-type cyclin associated cdc2 kinases in Xenopus turn on and off at different times in the cell cycle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

G1-specific cyclins of S. cerevisiae: cell cycle periodicity, regulation by mating pheromone, and association with the p34CDC28 protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

The A- and B-type cyclins of Drosophila are accumulated and destroyed in temporally distinct events that define separable phases of the G2-M transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

The roles of Drosophila cyclins A and B in mitotic control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

Universal control mechanism regulating onset of M-phase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

Drosophila cdc2 homologs: a functional homolog is coexpressed with a cognate variant

1 reference

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2 October 2017

Complementation of fission yeast cdc2ts and cdc25ts mutants identifies two cell cycle genes from Drosophila: a cdc2 homologue and string

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

Cyclin is a component of maturation-promoting factor from Xenopus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

2 October 2017

Sequence of two phosphorylated sites in the catalytic subunit of bovine cardiac muscle adenosine 3‘:5‘-monophosphate-dependent protein kinase

1 reference

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2 October 2017

Gene required in G1 for commitment to cell cycle and in G2 for control of mitosis in fission yeast.

1 reference

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11 July 2018

Primary structure homology between the product of yeast cell division control gene CDC28 and vertebrate oncogenes

1 reference

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Isolation of a transplantable cell line induced by the MC29 avian leukosis virus

1 reference

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11 July 2018

The cell cycle control gene cdc2+ of fission yeast encodes a protein kinase potentially regulated by phosphorylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

11 July 2018

Multiple phosphorylated forms of the product of the fission yeast cell division cycle gene cdc2+.

1 reference

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11 July 2018

The clam embryo protein cyclin A induces entry into M phase and the resumption of meiosis in Xenopus oocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

11 July 2018

Translation of cyclin mRNA is necessary for extracts of activated xenopus eggs to enter mitosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

11 July 2018

Transcripts of one of two Drosophila cyclin genes become localized in pole cells during embryogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

11 July 2018

Reversible tyrosine phosphorylation of cdc2: dephosphorylation accompanies activation during entry into mitosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

11 July 2018

Purification and characterisation of bovine brain protein kinase C isotypes alpha, beta and gamma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

11 July 2018

A cdc2-like protein is involved in the initiation of DNA replication in Xenopus egg extracts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

11 July 2018

Cell cycle control of DNA replication by a homologue from human cells of the p34cdc2 protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

11 July 2018

A bifunctional gene product involved in two phases of the yeast cell cycle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

24 September 2018

Phosphorylation of tyrosine-416 is not required for the transforming properties and kinase activity of pp60v-src.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

24 September 2018

Mutagenesis of Fujinami Sarcoma Virus: Evidence that tyrosine phosphorylation of P130gag-fps modulates its biological activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

24 September 2018

Evidence that the phosphorylation of tyrosine is essential for cellular transformation by Rous sarcoma virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

24 September 2018

Fission yeast p13 blocks mitotic activation and tyrosine dephosphorylation of the Xenopus cdc2 protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

24 September 2018

Triggering of cyclin degradation in interphase extracts of amphibian eggs by cdc2 kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

24 September 2018

A somatic cell-derived system for studying both early and late mitotic events in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452647

14 November 2018

Human cdc2 protein kinase is a major cell-cycle regulated tyrosine kinase substrate

1 reference

https://pubmed.ncbi.nlm.nih.gov/1846803

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A 60 kd cdc2-associated polypeptide complexes with the E1A proteins in adenovirus-infected cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/1846803

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dephosphorylation and activation of Xenopusp34 cdc2 protein kinase during the cell cycle

1 reference

https://pubmed.ncbi.nlm.nih.gov/1846803

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cdc2 protein kinase is complexed with both cyclin A and B: evidence for proteolytic inactivation of MPF

1 reference

https://pubmed.ncbi.nlm.nih.gov/1846803

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct activation of cdc2 with phosphatase: identification of p13suc1-sensitive and insensitive steps

1 reference

https://pubmed.ncbi.nlm.nih.gov/1846803

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of p34cdc2 protein kinase during mitosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/1846803

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of M-phase-specific histone H1 kinase by modification of the phosphorylation of its p34cdc2 and cyclin components

1 reference

https://pubmed.ncbi.nlm.nih.gov/1846803

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functionally homologous cell cycle control genes in budding and fission yeast

1 reference

https://pubmed.ncbi.nlm.nih.gov/1846803

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The fission yeast cdc2/cdc13/suc1 protein kinase: regulation of catalytic activity and nuclear localization

1 reference

https://pubmed.ncbi.nlm.nih.gov/1846803

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The fission yeast cell cycle control gene cdc2: isolation of a sequence suc1 that suppresses cdc2 mutant function

1 reference

https://pubmed.ncbi.nlm.nih.gov/1846803

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of cdc2 protein kinase during mitosis in human cells: cell cycle-dependent phosphorylation and subunit rearrangement

1 reference

https://pubmed.ncbi.nlm.nih.gov/1846803

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulated expression and phosphorylation of a possible mammalian cell-cycle control protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/1846803

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/J.1460-2075.1991.TB07951.X

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1846803

8 December 2022

1 reference

Europe PubMed Central

11 August 2017

1 reference

Europe PubMed Central

11 August 2017

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