(Q35921680)

11 August 2017

Identification of ubiquitin-specific protease 9X (USP9X) as a deubiquitinase acting on ubiquitin-peroxin 5 (PEX5) thioester conjugate (English)

1 reference

Ubiquitin specific peptidase 9 X-linked

11 August 2017

1 reference

thiol-dependent deubiquitinase

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Cláudia P Grou

1

1 reference

11 August 2017

Tânia Francisco

2

1 reference

11 August 2017

Tony A Rodrigues

3

1 reference

11 August 2017

Marta O Freitas

4

1 reference

11 August 2017

Manuel P Pinto

5

1 reference

11 August 2017

Andreia F Carvalho

6

1 reference

11 August 2017

Pedro Domingues

7

1 reference

11 August 2017

Stephen A Wood

8

1 reference

11 August 2017

José E Rodríguez-Borges

9

1 reference

11 August 2017

Clara Sá-Miranda

10

1 reference

11 August 2017

Marc Fransen

11

1 reference

11 August 2017

Jorge E Azevedo

12

1 reference

11 August 2017

language of work or name

English

0 references

publication date

27 February 2012

1 reference

Journal of Biological Chemistry

11 August 2017

1 reference

11 August 2017

287

1 reference

11 August 2017

16

1 reference

11 August 2017

12815-12827

1 reference

describes a project that uses

11 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3339989/fullTextXML

inferred from PubMed Central ID database lookup

cites work

α-Synuclein fate is determined by USP9X-regulated monoubiquitination

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High-yield expression in Escherichia coli and purification of mouse ubiquitin-activating enzyme E1.

2 October 2017

1 reference

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PEX5 protein binds monomeric catalase blocking its tetramerization and releases it upon binding the N-terminal domain of PEX14

2 October 2017

1 reference

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Ubp15p, a ubiquitin hydrolase associated with the peroxisomal export machinery

2 October 2017

1 reference

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Cysteine ubiquitination of PTS1 receptor Pex5p regulates Pex5p recycling

2 October 2017

1 reference

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Intraperoxisomal redox balance in mammalian cells: oxidative stress and interorganellar cross-talk

2 October 2017

1 reference

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USP47 is a deubiquitylating enzyme that regulates base excision repair by controlling steady-state levels of DNA polymerase β

2 October 2017

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Regulation of histone H2A and H2B deubiquitination and Xenopus development by USP12 and USP46.

2 October 2017

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2 October 2017

1 reference

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A global census of fission yeast deubiquitinating enzyme localization and interaction networks reveals distinct compartmentalization profiles and overlapping functions in endocytosis and polarity

2 October 2017

1 reference

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Peroxisomes as dynamic organelles: peroxisomal matrix protein import

2 October 2017

1 reference

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USP9x-mediated deubiquitination of EFA6 regulates de novo tight junction assembly

2 October 2017

1 reference

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Getting a camel through the eye of a needle: the import of folded proteins by peroxisomes

2 October 2017

1 reference

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Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival

2 October 2017

1 reference

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Ubiquitin-like sequence in ASK1 plays critical roles in the recognition and stabilization by USP9X and oxidative stress-induced cell death.

2 October 2017

1 reference

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The cytosolic domain of PEX3, a protein involved in the biogenesis of peroxisomes, binds membrane lipids

2 October 2017

1 reference

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Deubiquitinase activities required for hepatocyte growth factor-induced scattering of epithelial cells

2 October 2017

1 reference

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Mapping the cargo protein membrane translocation step into the PEX5 cycling pathway

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Defining the human deubiquitinating enzyme interaction landscape

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Solution structure of human Pex5.Pex14.PTS1 protein complexes obtained by small angle X-ray scattering

2 October 2017

1 reference

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Size and shape of protein molecules at the nanometer level determined by sedimentation, gel filtration, and electron microscopy.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes

2 October 2017

1 reference

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Peroxisome matrix and membrane protein biogenesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Spermatogenesis in a man with complete deletion of USP9Y

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Properties of the ubiquitin-pex5p thiol ester conjugate.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

The peroxisomal protein import machinery--a case report of transient ubiquitination with a new flavor.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Protein partners of deubiquitinating enzymes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

The ubiquitin E3 ligase MARCH7 is differentially regulated by the deubiquitylating enzymes USP7 and USP9X

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Members of the E2D (UbcH5) family mediate the ubiquitination of the conserved cysteine of Pex5p, the peroxisomal import receptor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Control of AMPK-related kinases by USP9X and atypical Lys(29)/Lys(33)-linked polyubiquitin chains

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Ubiquitination of mammalian Pex5p, the peroxisomal import receptor.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

A conserved cysteine is essential for Pex4p-dependent ubiquitination of the peroxisomal import receptor Pex5p

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

ElaD, a Deubiquitinating protease expressed by E. coli

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Characterization of the role of the receptors PEX5 and PEX7 in the import of proteins into glycosomes of Trypanosoma brucei

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Recognition of a Functional Peroxisome Type 1 Target by the Dynamic Import Receptor Pex5p

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Dynamic architecture of the peroxisomal import receptor Pex5p

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

The ubiquitin ligase itch is auto-ubiquitylated in vivo and in vitro but is protected from degradation by interacting with the deubiquitylating enzyme FAM/USP9X

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

PTS2 co-receptors: diverse proteins with common features

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Peroxisome targeting signal 1: is it really a simple tripeptide?

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

The import receptor Pex7p and the PTS2 targeting sequence

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Derivitization of the C-terminus of ubiquitin and ubiquitin-like proteins using intein chemistry: methods and uses

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

A genomic and functional inventory of deubiquitinating enzymes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Chromosome alignment and segregation regulated by ubiquitination of survivin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Shuttling mechanism of peroxisome targeting signal type 1 receptor Pex5: ATP-independent import and ATP-dependent export

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Functional role of the AAA peroxins in dislocation of the cycling PTS1 receptor back to the cytosol

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Pex5p, the peroxisomal cycling receptor, is a monomeric non-globular protein.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

The Arabidopsis peroxisomal targeting signal type 2 receptor PEX7 is necessary for peroxisome function and dependent on PEX5.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

A genomic analysis of rat proteases and protease inhibitors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

The FAM deubiquitylating enzyme localizes to multiple points of protein trafficking in epithelia, where it associates with E-cadherin and beta-catenin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Routing of Hansenula polymorpha alcohol oxidase: an alternative peroxisomal protein-sorting machinery

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Pex8p: an intraperoxisomal organizer of the peroxisomal import machinery

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Mammalian Pex14p: membrane topology and characterisation of the Pex14p-Pex14p interaction

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Chemistry-based functional proteomics reveals novel members of the deubiquitinating enzyme family

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Saccharomyces cerevisiae acyl-CoA oxidase follows a novel, non-PTS1, import pathway into peroxisomes that is dependent on Pex5p

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Peroxisomal targeting signal receptor Pex5p interacts with cargoes and import machinery components in a spatiotemporally differentiated manner: conserved Pex5p WXXXF/Y motifs are critical for matrix protein import

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

FAM deubiquitylating enzyme is essential for preimplantation mouse embryo development

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Characterization of the mammalian peroxisomal import machinery: Pex2p, Pex5p, Pex12p, and Pex14p are subunits of the same protein assembly

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Peroxisomal targeting signal-1 recognition by the TPR domains of human PEX5

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Analysis of the deubiquitinating enzymes of the yeast Saccharomyces cerevisiae

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Characterization of peroxisomal Pex5p from rat liver. Pex5p in the Pex5p-Pex14p membrane complex is a transmembrane protein

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Characterization of two related Drosophila gamma-tubulin complexes that differ in their ability to nucleate microtubules

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Recombinant human peroxisomal targeting signal receptor PEX5. Structural basis for interaction of PEX5 with PEX14.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

An isoform of pex5p, the human PTS1 receptor, is required for the import of PTS2 proteins into peroxisomes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Peroxisome targeting signal type 1 (PTS1) receptor is involved in import of both PTS1 and PTS2: studies with PEX5-defective CHO cell mutants

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Characterisation of the coding sequence and fine mapping of the human DFFRY gene and comparative expression analysis and mapping to the Sxrb interval of the mouse Y chromosome of the Dffry gene

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

The Drosophila developmental gene fat facets has a human homologue in Xp11.4 which escapes X-inactivation and has related sequences on Yq11.2

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Mutations in the PTS1 receptor gene, PXR1, define complementation group 2 of the peroxisome biogenesis disorders

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Identification and characterization of the putative human peroxisomal C-terminal targeting signal import receptor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Determination of molecular weights and frictional ratios of proteins in impure systems by use of gel filtration and density gradient centrifugation. Application to crude preparations of sulfite and hydroxylamine reductases

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Biogenesis of peroxisomes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Ubiquitin-aldehyde: a general inhibitor of ubiquitin-recycling processes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

Ubiquitin as a degradation signal

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

The Hansenula polymorpha PER3 gene is essential for the import of PTS1 proteins into the peroxisomal matrix

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339989

The N-terminal half of the peroxisomal cycling receptor Pex5p is a natively unfolded domain.

27 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.340158

The energetics of Pex5p-mediated peroxisomal protein import.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.340158

Characterization of the peroxisomal cycling receptor, Pex5p, using a cell-free in vitro import system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.340158

Cloning and expression analysis of a novel mouse gene with sequence similarity to the Drosophila fat facets gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.340158

Sex differences in sex chromosome gene expression in mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.340158

NEDD8: A new ataxin-3 interactor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.340158

In vitro synthesis of peroxisomal membrane polypeptides

21 January 2018

1 reference

12 December 2020

Insertion of Pex5p into the Peroxisomal Membrane Is Cargo Protein-dependent

1 reference

12 December 2020

Plant catalase is imported into peroxisomes by Pex5p but is distinct from typical PTS1 import

1 reference

12 December 2020

Ubiquitin adenylate: structure and role in ubiquitin activation

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M112.340158

1 reference

release_bneiktoyz5fjvknpxoeyrcbsiu

11 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/bneiktoyz5fjvknpxoeyrcbsiu

24 November 2022

mapped directly with Wikidata item

1 reference

11 August 2017

PubMed publication ID

22371489

1 reference