(Q28268269)

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The ubiquitin ligase itch is auto-ubiquitylated in vivo and in vitro but is protected from degradation by interacting with the deubiquitylating enzyme FAM/USP9X

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The ubiquitin ligase itch is auto-ubiquitylated in vivo and in vitro but is protected from degradation by interacting with the deubiquitylating enzyme FAM/USP9X (English)

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Annie Angers

6

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object named as

Stephen A Wood

5

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author name string

Rania Mouchantaf

1

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Bilal A Azakir

2

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Peter S McPherson

3

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Susan M Millard

4

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language of work or name

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publication date

15 December 2006

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Journal of Biological Chemistry

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281

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38738-47

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50

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Mechanisms underlying ubiquitination

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

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Ubiquitination of a yeast plasma membrane receptor signals its ligand-stimulated endocytosis

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Receptor downregulation and multivesicular-body sorting

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https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

The HECT domain ligase itch ubiquitinates endophilin and localizes to the trans-Golgi network and endosomal system

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

WW domain HECT E3s target Cbl RING finger E3s for proteasomal degradation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

Itchy, a Nedd4 Ubiquitin Ligase, Downregulates Latent Membrane Protein 2A Activity in B-Cell Signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

Dysregulation of T lymphocyte function in itchy mice: a role for Itch in TH2 differentiation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

Human ITCH is a coregulator of the hematopoietic transcription factor NF-E2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

The tight junction-specific protein occludin is a functional target of the E3 ubiquitin-protein ligase itch

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

Interaction between two ubiquitin-protein isopeptide ligases of different classes, CBLC and AIP4/ITCH.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

Recognition and ubiquitination of Notch by Itch, a hect-type E3 ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

Functional contribution of EEN to leukemogenic transformation by MLL-EEN fusion protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

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Conjugation and deconjugation of ubiquitin regulating the destiny of proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

Ubiquitin, proteasomes, and the regulation of intracellular protein degradation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

Rapid Ca2+-dependent decrease of protein ubiquitination at synapses

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

The ENTH domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

Jun turnover is controlled through JNK-dependent phosphorylation of the E3 ligase Itch

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

The ubiquitin-protein ligase E6-associated protein (E6-AP) serves as its own substrate.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

Conformational flexibility underlies ubiquitin ligation mediated by the WWP1 HECT domain E3 ligase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

Degradation of CFTR by the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

Functional annotation of deubiquitinating enzymes using RNA interference

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

Interaction of Grb2 via its Src homology 3 domains with synaptic proteins including synapsin I

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

The FAM deubiquitylating enzyme localizes to multiple points of protein trafficking in epithelia, where it associates with E-cadherin and beta-catenin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

Tandem MS analysis of brain clathrin-coated vesicles reveals their critical involvement in synaptic vesicle recycling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

Probability-based protein identification by searching sequence databases using mass spectrometry data

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

Cloning and expression analysis of a novel mouse gene with sequence similarity to the Drosophila fat facets gene.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

Endophilin regulates JNK activation through its interaction with the germinal center kinase-like kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

Identification of the major synaptojanin-binding proteins in brain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

WW domain sequence activity relationships identified using ligand recognition propensities of 42 WW domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

Stabilization of the E3 ubiquitin ligase Nrdp1 by the deubiquitinating enzyme USP8

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

Reciprocal activities between herpes simplex virus type 1 regulatory protein ICP0, a ubiquitin E3 ligase, and ubiquitin-specific protease USP7.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

Themes and variations on ubiquitylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

The ubiquitin-protein ligase Itch regulates p73 stability

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

Activation of the E3 ubiquitin ligase Itch through a phosphorylation-induced conformational change

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

A specific protein substrate for a deubiquitinating enzyme: Liquid facets is the substrate of Fat facets

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

The deubiquitinating enzyme Fam interacts with and stabilizes beta-catenin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

FAM deubiquitylating enzyme is essential for preimplantation mouse embryo development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

Fat facets and Liquid facets promote Delta endocytosis and Delta signaling in the signaling cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

Notch signalling in vertebrate neural development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

Epsins: adaptors in endocytosis?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

ENTH/ANTH proteins and clathrin-mediated membrane budding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605959200

21 January 2018

Identifiers

10.1074/JBC.M605959200

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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