(Q35922180)

English

Activation of natural killer T cells promotes M2 Macrophage polarization in adipose tissue and improves systemic glucose tolerance via interleukin-4 (IL-4)/STAT6 protein signaling axis in obesity

scientific article published on 6 March 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Activation of natural killer T cells promotes M2 Macrophage polarization in adipose tissue and improves systemic glucose tolerance via interleukin-4 (IL-4)/STAT6 protein signaling axis in obesity (English)

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

0 references

object named as

Shengyi Sun

2

0 references

object named as

Ling Qi

10

0 references

object named as

Sander Kersten

9

0 references

author name string

Yewei Ji

1

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Aimin Xu

3

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Prerna Bhargava

4

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Liu Yang

5

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Karen S L Lam

6

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Bin Gao

7

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Chih-Hao Lee

8

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

language of work or name

0 references

publication date

6 March 2012

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

287

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

17

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

13561-13571

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Impact of CD1d deficiency on metabolism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

2 October 2017

Mice lacking NKT cells but with a complete complement of CD8+ T-cells are not protected against the metabolic abnormalities of diet-induced obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

2 October 2017

Gr-1+ CD11b+ myeloid-derived suppressor cells suppress inflammation and promote insulin sensitivity in obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

2 October 2017

Innate and cytokine-driven signals, rather than microbial antigens, dominate in natural killer T cell activation during microbial infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

2 October 2017

B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

2 October 2017

Eosinophils sustain adipose alternatively activated macrophages associated with glucose homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

2 October 2017

Presumed guilty: natural killer T cell defects and human disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

2 October 2017

Type 2 diabetes as an inflammatory disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

2 October 2017

Angptl4 protects against severe proinflammatory effects of saturated fat by inhibiting fatty acid uptake into mesenteric lymph node macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

2 October 2017

STAT6 transcription factor is a facilitator of the nuclear receptor PPARγ-regulated gene expression in macrophages and dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

2 October 2017

Alternative activation of macrophages: mechanism and functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

2 October 2017

Control of macrophage activation and function by PPARs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

2 October 2017

Macrophages, inflammation, and insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

2 October 2017

Raising the NKT cell family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

2 October 2017

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

2 October 2017

Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

2 October 2017

Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

2 October 2017

Epigenetic regulation of the alternatively activated macrophage phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

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Lysosomal recycling terminates CD1d-mediated presentation of short and polyunsaturated variants of the NKT cell lipid antigen alphaGalCer

1 reference

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2 October 2017

The IRE1alpha-XBP1 pathway of the unfolded protein response is required for adipogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

2 October 2017

Harnessing invariant NKT cells in vaccination strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

2 October 2017

Preserved glucose tolerance in high-fat-fed C57BL/6 mice transplanted with PPARgamma-/-, PPARdelta-/-, PPARgammadelta-/-, or LXRalphabeta-/- bone marrow

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

2 October 2017

Obesity in C57BL/6J mice is characterized by adipose tissue hypoxia and cytotoxic T-cell infiltration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

2 October 2017

Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

2 October 2017

Obesity induces a phenotypic switch in adipose tissue macrophage polarization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

2 October 2017

The biology of NKT cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

2 October 2017

Toward an understanding of NKT cell biology: progress and paradoxes

1 reference

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2 October 2017

Glycolipid presentation to natural killer T cells differs in an organ-dependent fashion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

2 October 2017

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

2 October 2017

Obesity is associated with macrophage accumulation in adipose tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

2 October 2017

The response of natural killer T cells to glycolipid antigens is characterized by surface receptor down-modulation and expansion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

2 October 2017

A natural killer T (NKT) cell developmental pathway iInvolving a thymus-dependent NK1.1(-)CD4(+) CD1d-dependent precursor stage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

2 October 2017

Distinct functional lineages of human V(alpha)24 natural killer T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

2 October 2017

CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides

1 reference

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2 October 2017

CD1 recognition by mouse NK1+ T lymphocytes

1 reference

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2 October 2017

Recognition of a lipid antigen by CD1-restricted alpha beta+ T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

2 October 2017

An invariant T cell receptor alpha chain is used by a unique subset of major histocompatibility complex class I-specific CD4+ and CD4-8- T cells in mice and humans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

2 October 2017

Positive selection of mouse NK1+ T cells by CD1-expressing cortical thymocytes

1 reference

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2 October 2017

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

1 reference

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2 October 2017

Alternative M2 activation of Kupffer cells by PPARdelta ameliorates obesity-induced insulin resistance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

11 July 2018

Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

11 July 2018

Beta 2-microglobulin deficient mice lack CD4-8+ cytolytic T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

11 July 2018

Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8+ T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

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CD1b restricts the response of human CD4-8- T lymphocytes to a microbial antigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

11 July 2018

Natural killer T cells are involved in adipose tissues inflammation and glucose intolerance in diet-induced obese mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

24 September 2018

Invariant NKT cells and CD1d(+) cells amass in human omentum and are depleted in patients with cancer and obesity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

24 September 2018

Invariant natural killer T cells in asthma and chronic obstructive pulmonary disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

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Reduced CD4+ subset and Th1 bias of the human iNKT cells in Type 1 diabetes mellitus.

1 reference

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24 September 2018

Mechanism of CD1d-restricted natural killer T cell activation during microbial infection.

1 reference

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24 September 2018

A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells

1 reference

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24 September 2018

Role of NK1.1+ T cells in a TH2 response and in immunoglobulin E production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340139

24 September 2018

An invariant V alpha 24-J alpha Q/V beta 11 T cell receptor is expressed in all individuals by clonally expanded CD4-8- T cells

1 reference

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Sea-level fingerprinting as a direct test for the source of global meltwater pulse IA.

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The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection

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21 January 2018

The natural killer T-cell ligand α-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22396530

12 December 2020

based on heuristic

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NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R-STAT6 pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/22396530

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A thymic precursor to the NK T cell lineage

1 reference

https://pubmed.ncbi.nlm.nih.gov/22396530

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phase I study of the natural killer T-cell ligand alpha-galactosylceramide (KRN7000) in patients with solid tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22396530

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.350066

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

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