(Q35922459)

English

Induction of autophagy by palmitic acid via protein kinase C-mediated signaling pathway independent of mTOR (mammalian target of rapamycin).

scientific article published on 9 March 2012

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scholarly article

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Europe PubMed Central

11 August 2017

Induction of autophagy by palmitic acid via protein kinase C-mediated signaling pathway independent of mTOR (mammalian target of rapamycin). (English)

1 reference

Europe PubMed Central

11 August 2017

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6

object named as

Markus R Wenk

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Europe PubMed Central

11 August 2017

author name string

Shi Hao Tan

1

1 reference

Europe PubMed Central

11 August 2017

Guanghou Shui

2

1 reference

Europe PubMed Central

11 August 2017

Jing Zhou

3

1 reference

Europe PubMed Central

11 August 2017

Jasmine Jia'En Li

4

1 reference

Europe PubMed Central

11 August 2017

Boon-Huat Bay

5

1 reference

Europe PubMed Central

11 August 2017

Han-Ming Shen

7

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Europe PubMed Central

11 August 2017

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publication date

9 March 2012

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Europe PubMed Central

11 August 2017

number of pages

13

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Journal of Biological Chemistry

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Europe PubMed Central

11 August 2017

287

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Europe PubMed Central

11 August 2017

18

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Europe PubMed Central

11 August 2017

14364-14376

1 reference

Europe PubMed Central

11 August 2017

Differential roles of unsaturated and saturated fatty acids on autophagy and apoptosis in hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340233

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Mammalian triacylglycerol metabolism: synthesis, lipolysis, and signaling

1 reference

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Comparative plasma lipidome between human and cynomolgus monkey: are plasma polar lipids good biomarkers for diabetic monkeys?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340233

2 October 2017

A diacylglycerol-dependent signaling pathway contributes to regulation of antibacterial autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340233

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Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance.

1 reference

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2 October 2017

Altered lipid content inhibits autophagic vesicular fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340233

2 October 2017

Methods in mammalian autophagy research

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340233

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Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase

1 reference

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The role of the Atg1/ULK1 complex in autophagy regulation

1 reference

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2 October 2017

Acyl-CoA synthesis, lipid metabolism and lipotoxicity.

1 reference

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2 October 2017

Lipid oversupply, selective insulin resistance, and lipotoxicity: molecular mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340233

2 October 2017

Palmitic acid mediates hypothalamic insulin resistance by altering PKC-theta subcellular localization in rodents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340233

2 October 2017

Regulation mechanisms and signaling pathways of autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340233

2 October 2017

As a matter of fat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340233

2 October 2017

Autophagy regulates lipid metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340233

2 October 2017

ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340233

2 October 2017

PKC delta signaling: a dual role in regulating hypoxic stress-induced autophagy and apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340233

2 October 2017

Role of JNK1-dependent Bcl-2 phosphorylation in ceramide-induced macroautophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340233

2 October 2017

Protein kinase C function in muscle, liver, and beta-cells and its therapeutic implications for type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340233

2 October 2017

Sphingolipids, insulin resistance, and metabolic disease: new insights from in vivo manipulation of sphingolipid metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340233

2 October 2017

Protein kinase Ctheta is required for autophagy in response to stress in the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340233

2 October 2017

Autophagy fights disease through cellular self-digestion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340233

2 October 2017

Autophagy plays a protective role during zVAD-induced necrotic cell death.

1 reference

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2 October 2017

Mechanisms of disease:Molecular and metabolic mechanisms of insulin resistance and beta-cell failure in type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340233

2 October 2017

Autophagy: process and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340233

2 October 2017

Generation of cell lines with tetracycline-regulated autophagy and a role for autophagy in controlling cell size

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340233

2 October 2017

Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340233

2 October 2017

Autophagy and signaling: their role in cell survival and cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340233

2 October 2017

Growing roles for the mTOR pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340233

2 October 2017

Development by self-digestion: molecular mechanisms and biological functions of autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340233

2 October 2017

Ceramide-mediated macroautophagy involves inhibition of protein kinase B and up-regulation of beclin 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340233

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Lipopenia and skin barrier abnormalities in DGAT2-deficient mice

1 reference

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Lipotoxicity: when tissues overeat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340233

2 October 2017

Protein kinase C delta activation and translocation to the nucleus are required for fatty acid-induced apoptosis of insulin-secreting cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340233

2 October 2017

Triglyceride accumulation protects against fatty acid-induced lipotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340233

2 October 2017

Protein kinase C: structural and spatial regulation by phosphorylation, cofactors, and macromolecular interactions

1 reference

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A novel mouse model of lipotoxic cardiomyopathy

1 reference

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2 October 2017

Autophagy as a regulated pathway of cellular degradation

1 reference

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2 October 2017

Redistribution of substrates to adipose tissue promotes obesity in mice with selective insulin resistance in muscle

1 reference

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Obesity resistance and multiple mechanisms of triglyceride synthesis in mice lacking Dgat

1 reference

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2 October 2017

Protein kinase C activation by phorbol esters: do cysteine-rich regions and pseudosubstrate motifs play a role?

1 reference

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2 October 2017

Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet

1 reference

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Triacylglycerol synthesis in isolated fat cells. Studies on the microsomal diacylglycerol acyltransferase activity using ethanol-dispersed diacylglycerols.

1 reference

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11 July 2018

Palmitate induced insulin resistance by PKCtheta-dependent activation of mTOR/S6K pathway in C2C12 myotubes

1 reference

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24 September 2018

Protective role of autophagy in palmitate-induced INS-1 beta-cell death.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340233

24 September 2018

Fluorescent detection of lipid droplets and associated proteins

1 reference

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24 September 2018

Chronic exposure to free fatty acids or high glucose induces apoptosis in rat pancreatic islets: possible role of oxidative stress.

1 reference

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24 September 2018

Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340233

24 September 2018

Palmitate-induced apoptosis can occur through a ceramide-independent pathway

1 reference

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Toward one step analysis of cellular lipidomes using liquid chromatography coupled with mass spectrometry: application to Saccharomyces cerevisiae and Schizosaccharomyces pombe lipidomics

1 reference

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12 December 2020

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Identifiers

10.1074/JBC.M111.294157

1 reference

Europe PubMed Central

11 August 2017

1 reference

Europe PubMed Central

11 August 2017

1 reference

Europe PubMed Central

11 August 2017

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