(Q35925494)

English

Reversibly locking a protein fold in an active conformation with a disulfide bond: integrin alphaL I domains with high affinity and antagonist activity in vivo

scientific article published on 15 May 2001

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scholarly article

1 reference

Europe PubMed Central

11 August 2017

Reversibly locking a protein fold in an active conformation with a disulfide bond: integrin alphaL I domains with high affinity and antagonist activity in vivo (English)

1 reference

Europe PubMed Central

11 August 2017

protein folding

0 references

author name string

M Shimaoka

1

1 reference

Europe PubMed Central

11 August 2017

C Lu

2

1 reference

Europe PubMed Central

11 August 2017

R T Palframan

3

1 reference

Europe PubMed Central

11 August 2017

U H von Andrian

4

1 reference

Europe PubMed Central

11 August 2017

A McCormack

5

1 reference

Europe PubMed Central

11 August 2017

J Takagi

6

1 reference

Europe PubMed Central

11 August 2017

T A Springer

7

1 reference

Europe PubMed Central

11 August 2017

language of work or name

0 references

publication date

15 May 2001

1 reference

Europe PubMed Central

11 August 2017

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

11 August 2017

98

1 reference

Europe PubMed Central

11 August 2017

6009-6014

1 reference

Europe PubMed Central

11 August 2017

11

1 reference

Europe PubMed Central

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

2 October 2017

Locking in alternate conformations of the integrin alphaLbeta2 I domain with disulfide bonds reveals functional relationships among integrin domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

2 October 2017

An isolated, surface-expressed I domain of the integrin alphaLbeta2 is sufficient for strong adhesive function when locked in the open conformation with a disulfide bond.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

2 October 2017

Structure of a conserved receptor domain that regulates kinase activity: the cytoplasmic domain of bacterial taxis receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

2 October 2017

Integrin structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

2 October 2017

Computational design of an integrin I domain stabilized in the open high affinity conformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

2 October 2017

NMR and mutagenesis evidence for an I domain allosteric site that regulates lymphocyte function-associated antigen 1 ligand binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

2 October 2017

Structural basis of collagen recognition by integrin alpha2beta1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

2 October 2017

NMR solution structure of the inserted domain of human leukocyte function associated antigen-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

2 October 2017

The CC chemokine thymus-derived chemotactic agent 4 (TCA-4, secondary lymphoid tissue chemokine, 6Ckine, exodus-2) triggers lymphocyte function-associated antigen 1-mediated arrest of rolling T lymphocytes in peripheral lymph node high endothelial v

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

2 October 2017

Integrin leukocyte function-associated antigen-1-mediated cell binding can be activated by clustering of membrane rafts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

2 October 2017

A transgenic mouse model to analyze CD8(+) effector T cell differentiation in vivo

1 reference

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2 October 2017

The actin cytoskeleton regulates LFA-1 ligand binding through avidity rather than affinity changes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

2 October 2017

Molecular mechanisms of lymphocyte homing to peripheral lymph nodes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

2 October 2017

Crystal structure of the I domain from integrin alpha2beta1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

2 October 2017

Extreme stabilization of a thermolysin-like protease by an engineered disulfide bond

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

2 October 2017

Regulation of leukocyte integrin function: affinity vs. avidity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

2 October 2017

The role of the divalent cation in the structure of the I domain from the CD11a/CD18 integrin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

2 October 2017

Two conformations of the integrin A-domain (I-domain): a pathway for activation?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

2 October 2017

Comparative protein modelling by satisfaction of spatial restraints

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

2 October 2017

Crystal structure of the A domain from the alpha subunit of integrin CR3 (CD11b/CD18)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

2 October 2017

A binding interface on the I domain of lymphocyte function-associated antigen-1 (LFA-1) required for specific interaction with intercellular adhesion molecule 1 (ICAM-1)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

2 October 2017

Lock on/off disulfides identify the transmembrane signaling helix of the aspartate receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

2 October 2017

Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

2 October 2017

Crystal structure of the I-domain from the CD11a/CD18 (LFA-1, alpha L beta 2) integrin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

2 October 2017

WHAT IF: a molecular modeling and drug design program

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

2 October 2017

Intercellular adhesion molecule 3, a third adhesion counter-receptor for lymphocyte function-associated molecule 1 on resting lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

2 October 2017

Mapping the intercellular adhesion molecule-1 and -2 binding site on the inserted domain of leukocyte function-associated antigen-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

11 July 2018

Structural aspects of heterotrimeric G-protein signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

11 July 2018

Model building of disulfide bonds in proteins with known three-dimensional structure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

11 July 2018

A soluble form of intercellular adhesion molecule-1 inhibits rhinovirus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

11 July 2018

Molecular regulation of the interaction between leukocyte function-associated antigen-1 and soluble ICAM-1 by divalent metal cations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

24 September 2018

Direct evidence for two affinity states for lymphocyte function-associated antigen 1 on activated T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

24 September 2018

Global flexibility in a sensory receptor: a site-directed cross-linking approach.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

24 September 2018

Low affinity of cell surface lymphocyte function-associated antigen-1 (LFA-1) generates selectivity for cell-cell interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

14 November 2018

On the species specificity of the interaction of LFA-1 with intercellular adhesion molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=33413

14 November 2018

The alpha subunit cytoplasmic domain regulates the assembly and adhesiveness of integrin lymphocyte function-associated antigen-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/11353828

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

State-dependent disulfide cross-linking in rhodopsin

1 reference

https://pubmed.ncbi.nlm.nih.gov/11353828

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intravital microscopy of the peripheral lymph node microcirculation in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/11353828

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of molecular interactions between intercellular adhesion molecule-1 and leukocyte function- associated antigen-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/11353828

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemokines trigger immediate beta2 integrin affinity and mobility changes: differential regulation and roles in lymphocyte arrest under flow

1 reference

https://pubmed.ncbi.nlm.nih.gov/11353828

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T cell adhesion to intercellular adhesion molecule-1 (ICAM-1) is controlled by cell spreading and the activation of integrin LFA-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/11353828

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The I domain of integrin leukocyte function-associated antigen-1 is involved in a conformational change leading to high affinity binding to ligand intercellular adhesion molecule 1 (ICAM-1)

1 reference

https://pubmed.ncbi.nlm.nih.gov/11353828

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

I domain of beta 2 integrin lymphocyte function-associated antigen-1 contains a binding site for ligand intercellular adhesion molecule-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/11353828

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The top of the inserted-like domain of the integrin lymphocyte function-associated antigen-1 beta subunit contacts the alpha subunit beta -propeller domain near beta-sheet 3

1 reference

https://pubmed.ncbi.nlm.nih.gov/11353828

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.101130498

1 reference

Europe PubMed Central

11 August 2017

2001PNAS...98.6009S

0 references

1 reference

Europe PubMed Central

11 August 2017

1 reference

Europe PubMed Central

11 August 2017

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