(Q35932150)

11 August 2017

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title

Fleroxacin clinical pharmacokinetics (English)

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11 August 2017

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A. E. Stuck

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1551289

8 October 2022

D. K. Kim

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1551289

8 October 2022

F. J. Frey

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1551289

8 October 2022

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1551289

8 October 2022

publication date

1 February 1992

1 reference

Clinical Pharmacokinetics

11 August 2017

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11 August 2017

22

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11 August 2017

2

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11 August 2017

116-131

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https://scigraph.springernature.com/pub.10.2165/00003088-199222020-00003

11 August 2017

0 references

cites work

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12 December 2020

Fleroxacin (Ro 23-6240): activity in vitro against 355 enteropathogenic and non-fermentative gram-negative bacilli and Legionella pneumophila

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12 December 2020

Unique aspects of quinolone pharmacokinetics

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Inhibition of drug metabolism by quinolone antibiotics.

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In vitro activity of fleroxacin and 6 other antimicrobials against Acinetobacter anitratus

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Disposition of fleroxacin, a new trifluoroquinolone, and its metabolites. Pharmacokinetics in renal failure and influence of haemodialysis

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12 December 2020

Adverse reactions in a dose-ranging study with a new long-acting fluoroquinolone, fleroxacin

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12 December 2020

In-vitro activity of fleroxacin against Chlamydia trachomatis

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12 December 2020

Fleroxacin: safety, tolerance and effect on the faecal flora of healthy volunteers

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12 December 2020

Pharmacokinetics and body fluid penetration of fleroxacin in healthy volunteers

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12 December 2020

Determination of the new fluoroquinolone fleroxacin and its N-demethyl and N-oxide metabolites in plasma and urine by high-performance liquid chromatography with fluorescence detection

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12 December 2020

In vitro activities of seven quinolone derivatives against Neisseria gonorrhoeae.

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12 December 2020

In vivo tissue pharmacokinetics by fluorine magnetic resonance spectroscopy: a study of liver and muscle disposition of fleroxacin in humans

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12 December 2020

In vitro susceptibility of Xanthomonas (Pseudomonas) maltophilia to newer antimicrobial agents

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12 December 2020

Fleroxacin: in-vitro activity worldwide against 20,807 clinical isolates and comparison to ciprofloxacin and norfloxacin.

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Renal tolerance of fleroxacin in healthy volunteers

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12 December 2020

Clinical pharmacokinetics of ciprofloxacin

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12 December 2020

In vitro activity of the new 4-quinolone compound Ro 23-6240

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12 December 2020

The pharmacokinetics and therapeutic efficacy of fleroxacin and pefloxacin in a rat abscess model

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12 December 2020

The metabolism and pharmacokinetics of fleroxacin in healthy subjects

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12 December 2020

The antimicrobial activity of Fleroxacin RO 23-6240, a third generation fluoroquinolone derivative, tested in vitro

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12 December 2020

Renal handling of fleroxacin in rabbits, dogs, and humans

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12 December 2020

In vitro characterization of Ro 23-6240

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12 December 2020

Double-blind, dose-range-finding study of fleroxacin (RO 23-6240; AM-833) for treatment of complicated urinary tract infections

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12 December 2020

RO23-6240, a new orally absorbed quinolone: in vitro comparison with other broad-spectrum oral antimicrobial agents and imipenem

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12 December 2020

A new trifluorinated quinolone: Ro 23-6240 (AM 833).

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12 December 2020

In vitro activity of ceftriaxone, cefetamet (Ro 15-8074), ceftetrame (Ro 19-5247; T-2588), and fleroxacin (Ro 23-6240; AM-833) versus Neisseria gonorrhoeae and Haemophilus ducreyi

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12 December 2020

Pharmacokinetics and tissue penetration of fleroxacin after single and multiple 400- and 800-mg-dosage regimens

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12 December 2020

Comparative oral pharmacokinetics of fleroxacin and pefloxacin

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12 December 2020

Fluoroquinolone antibiotics. Microbiology, pharmacokinetics and clinical use.

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12 December 2020

Dose-ranging study of fleroxacin for treatment of uncomplicated Chlamydia trachomatis genital infections

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12 December 2020

In vitro activity of fleroxacin and 14 other antimicrobials against slime- and non-slime-producing Staphylococcus epidermidis

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12 December 2020

Fluoroquinolone antimicrobial agents

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12 December 2020

In vitro studies of fleroxacin (Ro 23-6240), a new trifluorinated quinolone derivative

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12 December 2020

Inhibition of Legionella pneumophila multiplication within human macrophages by fleroxacin

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12 December 2020

Comparative in-vitro activity of fleroxacin and other 6-fluoroquinolones against mycobacteria

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12 December 2020

In vitro and in vivo antibacterial activity of AM-833, a new quinolone derivative

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12 December 2020

In vitro activity of RO 23-6240 (AM-833): a new fluoroquinolone

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12 December 2020

Comparative in vitro activity of the new quinolone fleroxacin (RO 23-6240).

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12 December 2020

A simple isocratic high-pressure liquid chromatographic assay of quinolones in serum.

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12 December 2020

In vitro activity of new antibiotics against Haemophilus influenzae.

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12 December 2020

Pharmacokinetic disposition of quinolones in human body fluids and tissues

1 reference

12 December 2020

The penetration of fleroxacin into intra-abdominal abscesses

1 reference

12 December 2020

Comparative in vitro activity of fleroxacin (RO 23-6240) against Ureaplasma urealyticum and Mycoplasma hominis

1 reference

12 December 2020

Metabolism of fleroxacin in man

1 reference

12 December 2020

Penetration of fleroxacin into maxillary sinus mucosa and palatine tonsil

1 reference

12 December 2020

The activity of the 4 quinolone Ro 23 6240 and the cephalosporins Ro 15 8074 and Ro 19 5247 against penicillin sensitive and resistant gonococci.

1 reference

12 December 2020

In vitro susceptibility of Neisseria gonorrhoeae to RO 23-6240 and ciprofloxacin

1 reference

12 December 2020

Clinical pharmacokinetics and tolerance of fleroxacin in healthy male volunteers

1 reference

12 December 2020

Pharmacokinetics and metabolism of intravenous and oral fleroxacin in subjects with normal and impaired renal function and in patients on continuous ambulatory peritoneal dialysis

1 reference

12 December 2020

In vitro activity of Ro 23-6240, a new fluorinated 4-quinolone

1 reference

12 December 2020

In-vitro susceptibility of staphylococci to fleroxacin in comparison with six other quinolones

1 reference

12 December 2020

[In vitro activity of 5 new quinolones against Gardnerella vaginalis]

1 reference

12 December 2020

Susceptibility of 310 nonfermentative gram-negative bacteria to aztreonam, carumonam, ciprofloxacin, ofloxacin and fleroxacin

1 reference

12 December 2020

Pharmacokinetic interactions between theophylline and other medication (Part I).

1 reference

12 December 2020

Susceptibility of Brucella melitensis to fluoroquinolones

1 reference

12 December 2020

Comparative in-vitro activity of Ro 23-6240, a new trifluorinated quinolone

1 reference

12 December 2020

In-vitro activity of fleroxacin

1 reference

12 December 2020

Clinical pharmacokinetics of the newer antibacterial 4-quinolones

1 reference

12 December 2020

Comparative in vitro activity of cefetamet and fleroxacin against anaerobic bacteria

1 reference

12 December 2020

RO 23-6240 (AM-833), a new fluoroquinolone: in vitro antimicrobial activity and tentative disk diffusion interpretive criteria

1 reference

12 December 2020

In-vitro activity of fleroxacin (Ro 23-6240), a new fluoro-quinolone, and other agents, against Mycobacterium spp

1 reference

12 December 2020

Pharmacokinetics and tissue penetration of Ro 23-6240, a new trifluoroquinolone

1 reference

12 December 2020

Pseudomonas aeruginosa: in vitro susceptibility to antimicrobial drugs, single and combined, with and without defibrinated human blood

1 reference

12 December 2020

Steady-state pharmacokinetics of fleroxacin in patients with skin and skin structure infections

1 reference

12 December 2020

Susceptibilities of genital mycoplasmas to the newer quinolones as determined by the agar dilution method

1 reference

12 December 2020

In-vitro activity of fleroxacin against urinary tract and genital tract pathogens

1 reference

12 December 2020

Single and multiple dose pharmacokinetics of fleroxacin.

1 reference

12 December 2020

In-vitro activity of fleroxacin against isolates causing complicated urinary tract infections and concentrations in seminal and prostatic fluid and in prostatic adenoma tissue

1 reference

12 December 2020

Altered disposition of fleroxacin in patients with cystic fibrosis

1 reference

12 December 2020

Penetration of fleroxacin into prostatic secretion and prostatic adenoma tissue

1 reference

12 December 2020

In vitro activities of T-3262, NY-198, fleroxacin (AM-833; RO 23-6240), and other new quinolone agents against clinically isolated Chlamydia trachomatis strains

1 reference

12 December 2020

Safety of fleroxacin coadministered with theophylline to young and elderly volunteers

1 reference

12 December 2020

High-performance liquid chromatography for the determination of three new fluoroquinolones, fleroxacin, temafloxacin and A-64730, in biological fluids

1 reference

12 December 2020

In-vitro activity of fleroxacin compared with three other quinolones

1 reference

12 December 2020

In vitro activity of eight antimicrobial agents against non-penicillinase-producing gonococci isolated in Munich

1 reference

12 December 2020

A comparison of the penetration of two quinolones into intra-abdominal abscess

1 reference

12 December 2020

Intraphagocytic penetration of antibiotics

1 reference

12 December 2020

Fleroxacin concentrations in myometrium, ovary and fallopian tube

1 reference

12 December 2020

Single- and multiple-dose pharmacokinetics of fleroxacin, a trifluorinated quinolone, in humans

1 reference

12 December 2020

Disposition of fleroxacin, a new trifluoroquinolone, and its metabolites. Pharmacokinetics in elderly patients

1 reference

12 December 2020

Liquid-chromatographic determination of fleroxacin in serum and urine

1 reference

12 December 2020

In vitro activities of fleroxacin, cefetamet, ciprofloxacin, ceftriaxone, trimethoprim-sulfamethoxazole, and amoxicillin-clavulanic acid against rare members of the family Enterobacteriaceae primarily of human (clinical) origin

1 reference

12 December 2020

Comparative in vitro activity of RO 23-6240 (fleroxacin), a new 4-quinolone derivative

1 reference

12 December 2020

The 4-quinolone antibiotics: past, present, and future

1 reference

12 December 2020

Comparative in vitro activities of six new fluoroquinolones and other oral antimicrobial agents against Campylobacter pylori

1 reference

12 December 2020

In vitro evaluation of Ro 23-6240, a new fluorinated 4-quinolone.

1 reference

12 December 2020

In vitro activity of the new quinolone RO 23-6240 (AM-833) and the new cephalosporins RO 15-8074 and RO 19-5247 (T-2525) against Mycobacterium fortuitum and Mycobacterium chelonae

1 reference

12 December 2020

10.2165/00003088-199222020-00003

Identifiers

DOI

1 reference

Dimensions Publication ID

11 August 2017

0 references

1 reference