(Q35946087)

11 August 2017

Dll4-Notch signaling in Flt3-independent dendritic cell development and autoimmunity in mice (English)

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11 August 2017

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17

Miriam Merad

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11 August 2017

21

Iannis Aifantis

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11 August 2017

6

Hugo Mouquet

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11 August 2017

18

Ralph M Steinman

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11 August 2017

9

Juliana Idoyaga

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11 August 2017

Fabienne Billiard

1

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11 August 2017

Camille Lobry

2

1 reference

11 August 2017

Guillaume Darrasse-Jèze

3

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11 August 2017

Janelle Waite

4

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11 August 2017

Xia Liu

5

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11 August 2017

Amanda DaNave

7

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11 August 2017

Michelle Tait

8

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11 August 2017

Marylène Leboeuf

10

1 reference

11 August 2017

Christos A Kyratsous

11

1 reference

11 August 2017

Jacquelynn Burton

12

1 reference

11 August 2017

Julie Kalter

13

1 reference

11 August 2017

Apostolos Klinakis

14

1 reference

11 August 2017

Wen Zhang

15

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11 August 2017

Gavin Thurston

16

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11 August 2017

Andrew J Murphy

19

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11 August 2017

George D Yancopoulos

20

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11 August 2017

Dimitris Skokos

22

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11 August 2017

language of work or name

English

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publication date

30 April 2012

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Journal of Experimental Medicine

11 August 2017

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11 August 2017

209

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11 August 2017

5

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11 August 2017

1011-1028

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describes a project that uses

11 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3348095/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Inhibition of Notch signaling ameliorates insulin resistance in a FoxO1-dependent manner

1 reference

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Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain

2 October 2017

1 reference

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The earliest intrathymic precursors of CD8α(+) thymic dendritic cells correspond to myeloid-type double-negative 1c cells.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

Continuous activation of the CD122/STAT-5 signaling pathway during selection of antigen-specific regulatory T cells in the murine thymus

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

Dll1- and dll4-mediated notch signaling are required for homeostasis of intestinal stem cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

Regulation of dendritic cell differentiation and function by Notch and Wnt pathways

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

Origin and development of dendritic cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

Development of monocytes, macrophages, and dendritic cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

Dynamic regulation of notch 1 and notch 2 surface expression during T cell development and activation revealed by novel monoclonal antibodies

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

Feedback control of regulatory T cell homeostasis by dendritic cells in vivo

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

T-bet-deficient NOD mice are protected from diabetes due to defects in both T cell and innate immune system function

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

Notch and wingless signaling cooperate in regulation of dendritic cell differentiation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

In vivo analysis of dendritic cell development and homeostasis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

Thymus-homing peripheral dendritic cells constitute two of the three major subsets of dendritic cells in the steady-state thymus

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

Dendritic cell homeostasis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

Regulatory T cells and immune tolerance

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

Notch-RBP-J signaling controls the homeostasis of CD8- dendritic cells in the spleen.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

CD8- DCs induce IL-12-independent Th1 differentiation through Delta 4 Notch-like ligand in response to bacterial LPS

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

Developmental regulation of Foxp3 expression during ontogeny.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymus

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

Heterogeneity of thymic dendritic cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

Regulatory T cell lineage specification by the forkhead transcription factor foxp3

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

Regulation of lymphoid development, differentiation, and function by the Notch pathway.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

CD69 is an immunoregulatory molecule induced following activation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

Multiple immuno-regulatory defects in type-1 diabetes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

Notch 1-deficient common lymphoid precursors adopt a B cell fate in the thymus.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

Mice lacking flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells, and natural killer cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

Notch1 deficiency dissociates the intrathymic development of dendritic cells and T cells.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

Chemokines and cell migration in secondary lymphoid organs

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

The NOD mouse model of type 1 diabetes: as good as it gets?

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

Thymic dendritic cell precursors: relationship to the T lymphocyte lineage and phenotype of the dendritic cell progeny

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

Quantitative impact of thymic clonal deletion on the T cell repertoire

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

Characterization of c-kit positive intrathymic stem cells that are restricted to lymphoid differentiation.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

Delta-like 4 is indispensable in thymic environment specific for T cell development

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

Targeted expression of major histocompatibility complex (MHC) class II molecules demonstrates that dendritic cells can induce negative but not positive selection of thymocytes in vivo

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3348095

TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes.

11 July 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20111615

Ongoing Dll4-Notch signaling is required for T-cell homeostasis in the adult thymus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20111615

M-CSF: a novel plasmacytoid and conventional dendritic cell poietin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20111615

Deletion of Notch1 converts pro-T cells to dendritic cells and promotes thymic B cells by cell-extrinsic and cell-intrinsic mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20111615

Deficient T cell fate specification in mice with an induced inactivation of Notch1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20111615

Conditional ablation of MHC-II suggests an indirect role for MHC-II in regulatory CD4 T cell maintenance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20111615

Lasker Basic Medical Research Award. Dendritic cells: versatile controllers of the immune system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20111615

Expansion of peripheral naturally occurring T regulatory cells by Fms-like tyrosine kinase 3 ligand treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20111615

Ameliorating effects of anti-Dll4 mAb on Theiler's murine encephalomyelitis virus-induced demyelinating disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20111615

Autoimmune diabetes onset results from qualitative rather than quantitative age-dependent changes in pathogenic T-cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20111615

A Guardian of T Cell Fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20111615

T-cell apoptosis detected in situ during positive and negative selection in the thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20111615

Expansion of CD4+ CD25+ Foxp3+ T cells by bone marrow-derived dendritic cells

21 January 2018

1 reference

12 December 2020

Notch signaling in the immune system

1 reference

12 December 2020

The Transcription Factor PU.1 Controls Dendritic Cell Development and Flt3 Cytokine Receptor Expression in a Dose-Dependent Manner

1 reference

12 December 2020

Generation of murine dendritic cells from flt3-ligand-supplemented bone marrow cultures

1 reference

12 December 2020

Homeostasis of peripheral CD4+ T cells: IL-2R alpha and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbers

1 reference

12 December 2020

Dynamics of pathogenic and suppressor T cells in autoimmune diabetes development

1 reference

12 December 2020

Kinetics and efficacy of positive selection in the thymus of normal and T cell receptor transgenic mice

1 reference

12 December 2020

Cell expansion and growth arrest phases during the transition from precursor (CD4-8-) to immature (CD4+8+) thymocytes in normal and genetically modified mice

1 reference

12 December 2020

Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20111615

1 reference

11 August 2017

1 reference

11 August 2017

1 reference