(Q35947548)

English

microRNA-34a-Mediated Down-Regulation of the Microglial-Enriched Triggering Receptor and Phagocytosis-Sensor TREM2 in Age-Related Macular Degeneration

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scholarly article

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Europe PubMed Central

11 August 2017

microRNA-34a-Mediated Down-Regulation of the Microglial-Enriched Triggering Receptor and Phagocytosis-Sensor TREM2 in Age-Related Macular Degeneration (English)

1 reference

Europe PubMed Central

11 August 2017

0 references

1 reference

based on heuristic

inferred from title

Triggering receptor expressed on myeloid cells 2

1 reference

GOA release 2020-03-11

1 reference

based on heuristic

inferred from title

macular degeneration

1 reference

based on heuristic

inferred from title

Surjyadipta Bhattacharjee

object named as

Surjyadipta Bhattacharjee

1

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5

object named as

Walter J Lukiw

1 reference

Europe PubMed Central

11 August 2017

author name string

Yuhai Zhao

2

1 reference

Europe PubMed Central

11 August 2017

Prerna Dua

3

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Europe PubMed Central

11 August 2017

Evgeny I Rogaev

4

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Europe PubMed Central

11 August 2017

language of work or name

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publication date

7 March 2016

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Europe PubMed Central

11 August 2017

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Europe PubMed Central

11 August 2017

11

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Europe PubMed Central

11 August 2017

3

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Europe PubMed Central

11 August 2017

e0150211

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Europe PubMed Central

11 August 2017

copyright license

Creative Commons Attribution 4.0 International

7 March 2016

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April 2022 Public Data File from Crossref

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describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4780721/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Microglial genes regulating neuroinflammation in the progression of Alzheimer's disease.

1 reference

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MicroRNA (miRNA)-Mediated Pathogenetic Signaling in Alzheimer's Disease (AD).

1 reference

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2 October 2017

Role of microRNAs in the regulation of innate immune cells under neuroinflammatory conditions.

1 reference

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2 October 2017

The impact of microRNA gene regulation on the survival and function of mature cell types in the eye

1 reference

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2 October 2017

TREM2 enables amyloid β clearance by microglia

1 reference

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2 October 2017

Identification of differential microRNAs in cerebrospinal fluid and serum of patients with major depressive disorder

1 reference

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2 October 2017

TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models.

1 reference

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2 October 2017

TREM2 lipid sensing sustains the microglial response in an Alzheimer's disease model

1 reference

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2 October 2017

Significance of NF-κB as a pivotal therapeutic target in the neurodegenerative pathologies of Alzheimer's disease and multiple sclerosis

1 reference

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2 October 2017

Biology and therapy of inherited retinal degenerative disease: insights from mouse models

1 reference

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2 October 2017

Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis.

1 reference

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2 October 2017

TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis

1 reference

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2 October 2017

Coding variants in TREM2 increase risk for Alzheimer's disease

1 reference

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2 October 2017

Aluminum and its potential contribution to Alzheimer's disease (AD).

1 reference

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2 October 2017

The gastrointestinal tract microbiome and potential link to Alzheimer's disease

1 reference

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2 October 2017

Regulating amyloidogenesis through the natural triggering receptor expressed in myeloid/microglial cells 2 (TREM2).

1 reference

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2 October 2017

MicroRNA (miRNA): sequence and stability, viroid-like properties, and disease association in the CNS

1 reference

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2 October 2017

miR-34: from bench to bedside

1 reference

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2 October 2017

Apolipoprotein E, amyloid-beta, and neuroinflammation in Alzheimer's disease

1 reference

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2 October 2017

Regional distribution of synaptic markers and APP correlate with distinct clinicopathological features in sporadic and familial Alzheimer's disease

1 reference

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2 October 2017

Protein folding and misfolding in the neurodegenerative disorders: a review

1 reference

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2 October 2017

Cellular membrane fluidity in amyloid precursor protein processing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4780721

2 October 2017

MicroRNA and epilepsy: profiling, functions and potential clinical applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4780721

2 October 2017

Increased microRNA-34c abundance in Alzheimer's disease circulating blood plasma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4780721

2 October 2017

TREM2 variant p.R47H as a risk factor for sporadic amyotrophic lateral sclerosis

1 reference

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2 October 2017

Alzheimer disease: epidemiology, diagnostic criteria, risk factors and biomarkers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4780721

2 October 2017

The involvement of microRNAs in neurodegenerative diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4780721

2 October 2017

TREM2 and the neuroimmunology of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4780721

2 October 2017

Identification of a unique TGF-β-dependent molecular and functional signature in microglia

1 reference

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2 October 2017

Regulation of neurotropic signaling by the inducible, NF-kB-sensitive miRNA-125b in Alzheimer's disease (AD) and in primary human neuronal-glial (HNG) cells

1 reference

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2 October 2017

The innate immune system in Alzheimer's disease.

1 reference

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2 October 2017

microRNA-34a promotes DNA damage and mitotic catastrophe.

1 reference

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2 October 2017

Insights into TREM2 biology by network analysis of human brain gene expression data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4780721

2 October 2017

Seizures and epileptiform activity in the early stages of Alzheimer disease

1 reference

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2 October 2017

Expression of the phagocytosis-essential protein TREM2 is down-regulated by an aluminum-induced miRNA-34a in a murine microglial cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4780721

2 October 2017

Alzheimer's disease risk gene CD33 inhibits microglial uptake of amyloid beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4780721

2 October 2017

Regulation of TREM2 expression by an NF-кB-sensitive miRNA-34a

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4780721

2 October 2017

Structure, expression pattern and biological activity of molecular complex TREM-2/DAP12.

1 reference

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2 October 2017

Attenuated inflammatory response in triggering receptor expressed on myeloid cells 2 (TREM2) knock-out mice following stroke

1 reference

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2 October 2017

TREM2 Variants in Alzheimer's Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4780721

2 October 2017

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

1 reference

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2 October 2017

Human genetic individuality

1 reference

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2 October 2017

Transcriptional activation of microRNA-34a by NF-kappa B in human esophageal cancer cells

1 reference

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2 October 2017

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1 reference

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2 October 2017

NF-кB-regulated micro RNAs (miRNAs) in primary human brain cells

1 reference

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2 October 2017

Gene expression profile of THP-1 monocytes following knockdown of DAP12, a causative gene for Nasu-Hakola disease.

1 reference

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Circulatory miR34a as an RNAbased, noninvasive biomarker for brain aging

1 reference

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2 October 2017

Differential expression of miRNA-146a-regulated inflammatory genes in human primary neural, astroglial and microglial cells

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2 October 2017

Structural insights into functional and pathological amyloid

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2 October 2017

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2 October 2017

Differential regulation of interleukin-1 receptor-associated kinase-1 (IRAK-1) and IRAK-2 by microRNA-146a and NF-kappaB in stressed human astroglial cells and in Alzheimer disease.

1 reference

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2 October 2017

Mammalian microRNAs predominantly act to decrease target mRNA levels

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2 October 2017

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2 October 2017

miR-34a, a microRNA up-regulated in a double transgenic mouse model of Alzheimer's disease, inhibits bcl2 translation

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2 October 2017

TREM and TREM-like receptors in inflammation and disease

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2 October 2017

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2 October 2017

From expression to signaling: roles of TREM-1 and TREM-2 in innate immunity and bacterial infection.

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2 October 2017

An NF-kappaB-sensitive micro RNA-146a-mediated inflammatory circuit in Alzheimer disease and in stressed human brain cells

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2 October 2017

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2 October 2017

Physicochemical characteristics of soluble oligomeric Abeta and their pathologic role in Alzheimer's disease.

1 reference

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2 October 2017

Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo

1 reference

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2 October 2017

The aluminium-amyloid cascade hypothesis and Alzheimer's disease

1 reference

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2 October 2017

Heterogeneous expression of the triggering receptor expressed on myeloid cells-2 on adult murine microglia

1 reference

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2 October 2017

Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-kappa B

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2 October 2017

Retinal amyloid peptides and complement factor H in transgenic models of Alzheimer's disease

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27 July 2018

Molecular simulation of the primary and secondary structures of the Abeta(1-42)-peptide of Alzheimer's disease.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4780721

27 July 2018

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24 September 2018

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1 reference

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24 September 2018

Lack of genetic association between TREM2 and late-onset Alzheimer's disease in a Japanese population.

1 reference

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24 September 2018

Decreased expression of CD33 in peripheral mononuclear cells of Alzheimer's disease patients.

1 reference

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24 September 2018

Triggering receptor expressed on myeloid cells 2 knockdown exacerbates aging-related neuroinflammation and cognitive deficiency in senescence-accelerated mouse prone 8 mice.

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24 September 2018

TREM2 signaling, miRNA-34a and the extinction of phagocytosis

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24 September 2018

Variability in micro RNA (miRNA) abundance, speciation and complexity amongst different human populations and potential relevance to Alzheimer's disease (AD)

1 reference

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24 September 2018

Expression level of human miR-34a correlates with glioma grade and prognosis.

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24 September 2018

MicroRNA-34a regulates cardiac ageing and function.

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24 September 2018

Alzheimer's disease (AD) as a disorder of the plasma membrane

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24 September 2018

Variant TREM2 as risk factor for Alzheimer's disease

1 reference

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24 September 2018

Bacterial sensor triggering receptor expressed on myeloid cells-2 regulates the mucosal inflammatory response.

1 reference

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24 September 2018

Micro-RNA abundance and stability in human brain: specific alterations in Alzheimer's disease temporal lobe neocortex.

1 reference

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24 September 2018

Blockade of TREM-2 exacerbates experimental autoimmune encephalomyelitis.

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24 September 2018

Micro-RNA speciation in fetal, adult and Alzheimer's disease hippocampus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4780721

24 September 2018

Gene expression profiling of 12633 genes in Alzheimer hippocampal CA1: transcription and neurotrophic factor down-regulation and up-regulation of apoptotic and pro-inflammatory signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4780721

24 September 2018

TREM2 and neurodegenerative disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4780721

14 November 2018

Identifiers

10.1371/JOURNAL.PONE.0150211

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Europe PubMed Central

11 August 2017

2016PLoSO..1150211B

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1 reference

Europe PubMed Central

11 August 2017

1 reference

Europe PubMed Central

11 August 2017

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