(Q35950132)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17526734%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

title

Haploinsufficiency of Mdm2 and Mdm4 in tumorigenesis and development (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17526734%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

0 references

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17526734%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

author name string

Tamara Terzian

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17526734%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Yongxing Wang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17526734%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Carolyn S Van Pelt

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17526734%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Elisabeth L Travis

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17526734%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Guillermina Lozano

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17526734%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

language of work or name

English

0 references

publication date

25 May 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17526734%20AND%20SRC:MED&resulttype=core&format=json

Molecular and Cellular Biology

31 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17526734%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

volume

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17526734%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

page(s)

5479-5485

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17526734%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

issue

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17526734%20AND%20SRC:MED&resulttype=core&format=json

Tumor suppression and normal aging in mice with constitutively high p53 activity

31 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952101

Tissue-specific differences of p53 inhibition by Mdm2 and Mdm4.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952101

A single nucleotide polymorphism in the MDM2 gene: from a molecular and cellular explanation to clinical effect

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952101

A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952101

COP1, the negative regulator of p53, is overexpressed in breast and ovarian adenocarcinomas

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952101

Amplification of Mdmx (or Mdm4) directly contributes to tumor formation by inhibiting p53 tumor suppressor activity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952101

Sonic hedgehog signaling is required for expansion of granule neuron precursors and patterning of the mouse cerebellum

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952101

Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952101

Mdm2 haplo-insufficiency profoundly inhibits Myc-induced lymphomagenesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952101

mdm2 Is critical for inhibition of p53 during lymphopoiesis and the response to ionizing irradiation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952101

Mdm4 (Mdmx) regulates p53-induced growth arrest and neuronal cell death during early embryonic mouse development

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952101

Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952101

Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952101

Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952101

Tumor spectrum analysis in p53-mutant mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952101

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952101

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1952101

Loss of one but not two mdm2 null alleles alters the tumour spectrum in p53 null mice

2 October 2017

1 reference

12 December 2020

Achilles' heel of cancer?

1 reference

12 December 2020

An alternatively spliced HDM2 product increases p53 activity by inhibiting HDM2

1 reference

12 December 2020

mdmx is a negative regulator of p53 activity in vivo

1 reference

12 December 2020

Cell cycle control and cancer

1 reference

12 December 2020

The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

1 reference

12 December 2020

Identifiers

DOI

10.1128/MCB.00555-06

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17526734%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17526734%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference