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Roles for microRNAs in conferring robustness to biological processes
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scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
3351105
retrieved
11 August 2017
title
Roles for microRNAs in conferring robustness to biological processes
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3351105
retrieved
11 August 2017
main subject
microRNA
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based on heuristic
inferred from title
author name string
Margaret S Ebert
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
3351105
retrieved
11 August 2017
Phillip A Sharp
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
3351105
retrieved
11 August 2017
language of work or name
English
0 references
publication date
1 April 2012
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stated in
Europe PubMed Central
PMCID
3351105
retrieved
11 August 2017
published in
Cell
1 reference
stated in
Europe PubMed Central
PMCID
3351105
retrieved
11 August 2017
volume
149
1 reference
stated in
Europe PubMed Central
PMCID
3351105
retrieved
11 August 2017
page(s)
515-524
1 reference
stated in
Europe PubMed Central
PMCID
3351105
retrieved
11 August 2017
issue
3
1 reference
stated in
Europe PubMed Central
PMCID
3351105
retrieved
11 August 2017
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The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-α receptor
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A Drosophila genetic screen yields allelic series of core microRNA biogenesis factors and reveals post-developmental roles for microRNAs
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Weak seed-pairing stability and high target-site abundance decrease the proficiency of lsy-6 and other microRNAs
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MicroRNAs can generate thresholds in target gene expression
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Poly(ADP-ribose) regulates stress responses and microRNA activity in the cytoplasm.
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A latent pro-survival function for the mir-290-295 cluster in mouse embryonic stem cells
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The role of incoherent microRNA-mediated feedforward loops in noise buffering
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miRNA regulation of Sdf1 chemokine signaling provides genetic robustness to germ cell migration
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Mammalian microRNAs predominantly act to decrease target mRNA levels
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Loss of individual microRNAs causes mutant phenotypes in sensitized genetic backgrounds in C. elegans
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Drosophila microRNAs 263a/b confer robustness during development by protecting nascent sense organs from apoptosis
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MicroRNA let-7a inhibits proliferation of human prostate cancer cells in vitro and in vivo by targeting E2F2 and CCND2.
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Target mRNA abundance dilutes microRNA and siRNA activity
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Differential regulation of microRNA stability
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Cell-cycle regulator E2F1 and microRNA-223 comprise an autoregulatory negative feedback loop in acute myeloid leukemia
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An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation
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Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression
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MicroRNAs and metazoan macroevolution: insights into canalization, complexity, and the Cambrian explosion
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Progressive lengthening of 3' untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development.
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MicroRNAs: target recognition and regulatory functions
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2 October 2017
Most mammalian mRNAs are conserved targets of microRNAs
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2 October 2017
A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition
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2 October 2017
The impact of microRNAs on protein output
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Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sites
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A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
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2 October 2017
Dicer inactivation leads to progressive functional and structural degeneration of the mouse retina
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Temporal reciprocity of miRNAs and their targets during the maternal-to-zygotic transition in Drosophila
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Suppression of non-small cell lung tumor development by the let-7 microRNA family
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MicroRNAs and the advent of vertebrate morphological complexity
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2 October 2017
Most Caenorhabditis elegans microRNAs are individually not essential for development or viability
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Target protectors reveal dampening and balancing of Nodal agonist and antagonist by miR-430.
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2 October 2017
MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells
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2 October 2017
MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammals
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Evolutionary conservation of microRNA regulatory circuits: an examination of microRNA gene complexity and conserved microRNA-target interactions through metazoan phylogeny
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2 October 2017
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2 October 2017
miR-181a is an intrinsic modulator of T cell sensitivity and selection
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Control of stress-dependent cardiac growth and gene expression by a microRNA
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2 October 2017
Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation
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Transcripts targeted by the microRNA-16 family cooperatively regulate cell cycle progression
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2 October 2017
Phenotypic consequences of promoter-mediated transcriptional noise
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MicroRNA-9a ensures the precise specification of sensory organ precursors in Drosophila
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Canalization of development by microRNAs
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2 October 2017
Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs
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2 October 2017
Cell-type-specific signatures of microRNAs on target mRNA expression
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A microRNA mediates EGF receptor signaling and promotes photoreceptor differentiation in the Drosophila eye
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2 October 2017
Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolution
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2 October 2017
A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis
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2 October 2017
The widespread impact of mammalian MicroRNAs on mRNA repression and evolution
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2 October 2017
LIN-12/Notch activation leads to microRNA-mediated down-regulation of Vav in C. elegans
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Noise in gene expression: origins, consequences, and control
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2 October 2017
The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans
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MicroRNA expression profiles classify human cancers
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2 October 2017
Noise propagation in gene networks
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2 October 2017
Biological robustness
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2 October 2017
Summing up the noise in gene networks
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2 October 2017
Regulation of noise in the expression of a single gene
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Hsp90 as a capacitor for morphological evolution
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PubMed Central
reference URL
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2 October 2017
Genome-wide dissection of microRNA functions and cotargeting networks using gene set signatures
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11 July 2018
Architecture-dependent noise discriminates functionally analogous differentiation circuits.
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24 September 2018
Redefining microRNA targets
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PubMed Central
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24 September 2018
A C. elegans genome-scale microRNA network contains composite feedback motifs with high flux capacity.
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PubMed Central
reference URL
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24 September 2018
Stochastic switching as a survival strategy in fluctuating environments
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PubMed Central
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retrieved
24 September 2018
Identifiers
DOI
10.1016/J.CELL.2012.04.005
1 reference
stated in
Europe PubMed Central
PMCID
3351105
retrieved
11 August 2017
PMCID
3351105
1 reference
stated in
Europe PubMed Central
PMCID
3351105
retrieved
11 August 2017
PubMed ID
22541426
1 reference
stated in
Europe PubMed Central
PMCID
3351105
retrieved
11 August 2017
ResearchGate publication ID
224865278
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