(Q35956168)

11 August 2017

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title

Glutathione-dependent bioactivation of haloalkanes and haloalkenes (English)

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11 August 2017

Anders MW

1

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11 August 2017

language of work or name

English

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publication date

1 October 2004

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11 August 2017

published in

Drug Metabolism Reviews

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11 August 2017

volume

36

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11 August 2017

issue

3-4

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11 August 2017

page(s)

583-594

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Isolation from rat kidney of a cytosolic high molecular weight cysteine-S-conjugate beta-lyase with activity toward leukotriene E4.

11 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033451

Metabolism of dihalomethanes to formaldehyde and inorganic halide--II. Studies on the mechanism of the reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033451

Dichloromethane metabolism to formaldehyde and reaction of formaldehyde with nucleic acids in hepatocytes of rodents and humans with and without glutathione S-transferase T1 and M1 genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033451

Nephrotoxicity of mercapturic acids of three structurally related 2,2-difluoroethylenes in the rat. Indications for different bioactivation mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033451

Toxic, halogenated cysteine S-conjugates and targeting of mitochondrial enzymes of energy metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033451

Role of cytochrome P450 and glutathione S-transferase alpha in the metabolism and cytotoxicity of trichloroethylene in rat kidney.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033451

Effects of AT-125 on the nephrotoxicity of hexachloro-1,3-butadiene in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033451

Bioactivation mechanism of the cytotoxic and nephrotoxic S-conjugate S-(2-chloro-1,1,2-trifluoroethyl)-L-cysteine

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033451

Thioacylating intermediates as metabolites of S-(1,2-dichlorovinyl)-L-cysteine and S-(1,2,2-trichlorovinyl)-L-cysteine formed by cysteine conjugate beta-lyase

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033451

Bioactivation of nephrotoxic haloalkenes by glutathione conjugation: formation of toxic and mutagenic intermediates by cysteine conjugate beta-lyase

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033451

Mechanism of S-(1,2-dichlorovinyl)glutathione-induced nephrotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033451

Structure-mutagenicity and structure-cytotoxicity studies on bromine-containing cysteine S-conjugates and related compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033451

Activation of dihaloalkanes by thiol-dependent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033451

Immunochemical detection of covalently modified kidney proteins in S-(1,1,2,2,-tetrafluoroethyl)-L-cysteine-treated rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033451

Formation of mitochondrial phospholipid adducts by nephrotoxic cysteine conjugate metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033451

Isolation and characterization of N7-guanyl adducts derived from 1,2-dibromo-3-chloropropane

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033451

Glutathione-mediated binding of dibromoalkanes to DNA: specificity of rat glutathione-S-transferases and dibromoalkane structure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033451

Structure-activity relationship for the biotransformation of haloalkenes by rat liver microsomal glutathione transferase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033451

Computational and experimental studies on the distribution of addition and substitution products of the microsomal glutathione transferase 1-catalyzed conjugation of glutathione with fluoroalkenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033451

Role of renal cysteine conjugate beta-lyase in the mechanism of compound A nephrotoxicity in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033451

Role of the renal cysteine conjugate beta-lyase pathway in inhaled compound A nephrotoxicity in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033451

Metabolism of dihalomethanes to carbon monoxide--III. Studies on the mechanism of the reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033451

Acivicin-induced alterations in renal and hepatic glutathione concentrations and in gamma-glutamyltransferase activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033451

Formation and mass spectrometric analysis of DNA and nucleoside adducts by S-(1-acetoxymethyl)glutathione and by glutathione S-transferase-mediated activation of dihalomethanes

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033451

Studies of the mechanism of nephrotoxicity of compound A in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033451

Evidence for formation of an S-[2-(N7-guanyl)ethyl]glutathione adduct in glutathione-mediated binding of the carcinogen 1,2-dibromoethane to DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033451

The mutagenic effect of 1,2-dichloroethane on Salmonella typhimurium. II. activation by the isolated perfused rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033451

In vitro metabolism of methylene chloride in human and animal tissues: use in physiologically based pharmacokinetic models

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033451

Expression of mammalian glutathione S-transferase 5-5 in Salmonella typhimurium TA1535 leads to base-pair mutations upon exposure to dihalomethanes

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033451

Stereoselective activation of vicinal dihalogen compounds to mutagens by glutathione conjugation

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033451

Role for an episulfonium ion in S-(2-chloroethyl)-DL-cysteine-induced cytotoxicity and its reaction with glutathione

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033451

Conjugation of haloalkanes by bacterial and mammalian glutathione transferases: mono- and dihalomethanes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033451

21 January 2018

Identifiers

DOI

10.1081/DMR-200033451

1 reference

release_k5p62kzmmranth3rwqszbq7fi4

11 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/k5p62kzmmranth3rwqszbq7fi4

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference