(Q35956294)

11 August 2017

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title

Pathophysiology of stroke: lessons from animal models (English)

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11 August 2017

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2

Ulrich Dirnagl

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Andreas Meisel

object named as

Andreas Meisel

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3

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Philipp Mergenthaler

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1

object named as

Philipp Mergenthaler

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PubMed ID

15554412

11 August 2017

language of work or name

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1 December 2004

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11 August 2017

Metabolic Brain Disease

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11 August 2017

19

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11 August 2017

3-4

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11 August 2017

151-167

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https://scigraph.springernature.com/pub.10.1023/b:mebr.0000043966.46964.e6

11 August 2017

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cites work

Correlation between peri-infarct DC shifts and ischaemic neuronal damage in rat.

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12 December 2020

Timing for fever-related brain damage in acute ischemic stroke.

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12 December 2020

Admission body temperature predicts long-term mortality after acute stroke: the Copenhagen Stroke Study

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12 December 2020

Targeting gene-modified hematopoietic cells to the central nervous system: use of green fluorescent protein uncovers microglial engraftment.

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12 December 2020

Fusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes

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12 December 2020

Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage

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12 December 2020

Acidosis and ischemic brain damage.

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12 December 2020

Why do all drugs work in animals but none in stroke patients? 1. Drugs promoting cerebral blood flow

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12 December 2020

In Vivo Delivery of a Bcl-xL Fusion Protein Containing the TAT Protein Transduction Domain Protects against Ischemic Brain Injury and Neuronal Apoptosis

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12 December 2020

Intercellular adhesion molecule-1-deficient mice are less susceptible to cerebral ischemia-reperfusion injury.

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12 December 2020

Early appearance of activated matrix metalloproteinase-9 after focal cerebral ischemia in mice: a possible role in blood-brain barrier dysfunction

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12 December 2020

Endothelial ICAM-1 expression associated with inflammatory cell response in human ischemic stroke.

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12 December 2020

Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment

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12 December 2020

Effect of hyperthermia on glutamate release in ischemic penumbra after middle cerebral artery occlusion in rats

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12 December 2020

Neurodegenerative disorders and ischemic brain diseases.

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12 December 2020

Inflammation and stroke: putative role for cytokines, adhesion molecules and iNOS in brain response to ischemia

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12 December 2020

Toward wisdom from failure: lessons from neuroprotective stroke trials and new therapeutic directions

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12 December 2020

Clinical trials in acute stroke: why have they not been successful?

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12 December 2020

Cyclooxygenase-2 is induced globally in infarcted human brain.

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12 December 2020

Caspase activation and neuroprotection in caspase-3- deficient mice after in vivo cerebral ischemia and in vitro oxygen glucose deprivation

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12 December 2020

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12 December 2020

Polymorphonuclear leukocytes occlude capillaries following middle cerebral artery occlusion and reperfusion in baboons

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12 December 2020

Stroke-induced immunodeficiency promotes spontaneous bacterial infections and is mediated by sympathetic activation reversal by poststroke T helper cell type 1-like immunostimulation

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12 December 2020

NAD+ repletion prevents PARP-1-induced glycolytic blockade and cell death in cultured mouse astrocytes

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12 December 2020

Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia.

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12 December 2020

The prognostic significance of subfebrility and fever in ischaemic cerebral infarction

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12 December 2020

Expression of fractalkine and its receptor, CX3CR1, in response to ischaemia-reperfusion brain injury in the rat.

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12 December 2020

Pathobiology of ischaemic stroke: an integrated view

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12 December 2020

Neogenesis of cerebellar Purkinje neurons from gene-marked bone marrow cells in vivo.

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12 December 2020

Contrasting mechanisms for suppression of macrophage cytokine release by transforming growth factor-beta and interleukin-10.

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12 December 2020

Neuronal regeneration after stroke

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12 December 2020

Matrix metalloproteinases and TIMPs are associated with blood-brain barrier opening after reperfusion in rat brain.

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12 December 2020

Immunologic tolerance to myelin basic protein decreases stroke size after transient focal cerebral ischemia

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12 December 2020

Effects of poststroke pyrexia on stroke outcome : a meta-analysis of studies in patients

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12 December 2020

Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia

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12 December 2020

Interleukin-10 in the brain.

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12 December 2020

Mechanisms, challenges and opportunities in stroke

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12 December 2020

Induction of mucosal tolerance to E-selectin prevents ischemic and hemorrhagic stroke in spontaneously hypertensive genetically stroke-prone rats.

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12 December 2020

The effect of pneumonia on mortality among patients hospitalized for acute stroke

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12 December 2020

Antibody to the alpha4 integrin decreases infarct size in transient focal cerebral ischemia in rats

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12 December 2020

Expression of bcl-2 from a defective herpes simplex virus-1 vector limits neuronal death in focal cerebral ischemia

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12 December 2020

Targeting the central nervous system inflammatory response in ischemic stroke.

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12 December 2020

Thresholds in cerebral ischemia - the ischemic penumbra

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12 December 2020

Intravenous TAT-Bcl-Xl is protective after middle cerebral artery occlusion in mice

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12 December 2020

Aminoguanidine ameliorates and L-arginine worsens brain damage from intraluminal middle cerebral artery occlusion.

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12 December 2020

Cortical negative DC deflections following middle cerebral artery occlusion and KCl-induced spreading depression: effect on blood flow, tissue oxygenation, and electroencephalogram

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12 December 2020

Inhibition of polymorphonuclear leukocyte adherence suppresses no-reflow after focal cerebral ischemia in baboons

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12 December 2020

Ischemic tolerance and endogenous neuroprotection

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12 December 2020

Inflammation and infection in clinical stroke

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12 December 2020

Anti-intercellular adhesion molecule-1 antibody reduces ischemic cell damage after transient but not permanent middle cerebral artery occlusion in the Wistar rat

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12 December 2020

The temporal profiles of ICAM-1 protein and mRNA expression after transient MCA occlusion in the rat

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12 December 2020

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

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12 December 2020

Cell transplantation for stroke

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12 December 2020

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12 December 2020

Adoptive transfer of myelin basic protein-tolerized splenocytes to naive animals reduces infarct size: a role for lymphocytes in ischemic brain injury?

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12 December 2020

Ischemic brain injury is mediated by the activation of poly(ADP-ribose)polymerase.

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12 December 2020

Cellular survival: a play in three Akts

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12 December 2020

Cause-specific mortality after first cerebral infarction: a population-based study.

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12 December 2020

Transforming growth factor-beta 1 prevents glutamate neurotoxicity in rat neocortical cultures and protects mouse neocortex from ischemic injury in vivo.

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12 December 2020

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12 December 2020

Hypoxia-induced stroke tolerance in the mouse is mediated by erythropoietin.

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12 December 2020

Delayed postischemic hyperthermia in awake rats worsens the histopathological outcome of transient focal cerebral ischemia

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12 December 2020

Nosocomial pneumonia after acute stroke: implications for neurological intensive care medicine.

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12 December 2020

Transgenic mice overexpressing XIAP in neurons show better outcome after transient cerebral ischemia.

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12 December 2020

Screening for dysphagia and aspiration in acute stroke: a systematic review

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12 December 2020

Neuroprotective effects of TNF binding protein in focal cerebral ischemia.

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12 December 2020

Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors

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12 December 2020

Complications after acute stroke

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12 December 2020

Apoptosis and caspases in neurodegenerative diseases

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12 December 2020

Repeated negative DC deflections in rat cortex following middle cerebral artery occlusion are abolished by MK-801: effect on volume of ischemic injury

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12 December 2020

Potassium-induced cortical spreading depressions during focal cerebral ischemia in rats: contribution to lesion growth assessed by diffusion-weighted NMR and biochemical imaging.

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12 December 2020

Mitochondrial contributions to tissue damage in stroke

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12 December 2020

A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window

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12 December 2020

Murine models define the role of TGF-beta as a master regulator of immune cell function

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12 December 2020

Neurogenesis after ischaemic brain insults

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12 December 2020

Diffusion-weighted NMR imaging: application to experimental focal cerebral ischemia

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12 December 2020

Attenuated stroke severity after prodromal TIA: a role for ischemic tolerance in the brain?

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12 December 2020

Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor

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12 December 2020

Anti-CD11b monoclonal antibody reduces ischemic cell damage after transient focal cerebral ischemia in rat.

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12 December 2020

In vivo evidence that erythropoietin protects neurons from ischemic damage

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12 December 2020

The biochemistry of apoptosis

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12 December 2020

Interaction between XIAP and Smac/DIABLO in the mouse brain after transient focal cerebral ischemia.

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12 December 2020

Apoptotic and antiapoptotic mechanisms in stroke.

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12 December 2020

Preventive antibacterial treatment improves the general medical and neurological outcome in a mouse model of stroke

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12 December 2020

Signaling of Cell Death and Cell Survival Following Focal Cerebral Ischemia: Life and Death Struggle in the Penumbra

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12 December 2020

Adventures in the pathophysiology of brain ischemia: penumbra, gene expression, neuroprotection: the 2002 Thomas Willis Lecture

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12 December 2020

Induction of spreading depression in the ischemic hemisphere following experimental middle cerebral artery occlusion: effect on infarct morphology.

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12 December 2020

Apoptosis and brain ischaemia

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12 December 2020

Delayed reduction of ischemic brain injury and neurological deficits in mice lacking the inducible nitric oxide synthase gene.

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12 December 2020

Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia.

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12 December 2020

Serial analysis of gene expression identifies metallothionein-II as major neuroprotective gene in mouse focal cerebral ischemia.

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12 December 2020

Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia.

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12 December 2020

14-3-3 proteins and survival kinases cooperate to inactivate BAD by BH3 domain phosphorylation

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12 December 2020

Lack of interleukin-6 expression is not protective against focal central nervous system ischemia

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12 December 2020

Noninvasive near infrared spectroscopy monitoring of regional cerebral blood oxygenation changes during peri-infarct depolarizations in focal cerebral ischemia in the rat.

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12 December 2020

Temperature changes of > or = 1 degree C alter functional neurologic outcome and histopathology in a canine model of complete cerebral ischemia

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12 December 2020

Penumbral probability thresholds of cortical flumazenil binding and blood flow predicting tissue outcome in patients with cerebral ischaemia

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12 December 2020

Aspiration pneumonitis and aspiration pneumonia

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12 December 2020

Increased expression of adhesion molecule CD18 (LFA-1beta) on the leukocytes of peripheral blood in patients with acute ischemic stroke.

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12 December 2020

The role of peroxynitrite in nitric oxide-mediated toxicity.

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12 December 2020

Erythropoietin therapy for acute stroke is both safe and beneficial

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12 December 2020

The progression and topographic distribution of interleukin-1beta expression after permanent middle cerebral artery occlusion in the rat.

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12 December 2020

Reduced susceptibility to ischemic brain injury and N-methyl-D-aspartate-mediated neurotoxicity in cyclooxygenase-2-deficient mice.

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12 December 2020

Microglia and macrophages are the major source of tumor necrosis factor in permanent middle cerebral artery occlusion in mice

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12 December 2020

Neurodegenerative and neuroprotective effects of tumor Necrosis factor (TNF) in retinal ischemia: opposite roles of TNF receptor 1 and TNF receptor 2.

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12 December 2020

Matrix metalloproteinases increase very early during experimental focal cerebral ischemia

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12 December 2020

Metalloproteinase inhibition reduces thrombolytic (tissue plasminogen activator)-induced hemorrhage after thromboembolic stroke.

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12 December 2020

Medical and neurological complications of ischemic stroke: experience from the RANTTAS trial. RANTTAS Investigators

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12 December 2020

Erythropoietin is a paracrine mediator of ischemic tolerance in the brain: evidence from an in vitro model

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12 December 2020

IL-10 reduces rat brain injury following focal stroke.

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12 December 2020

Glucose and the ischemic brain: a sour grape or a sweet treat?

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12 December 2020

Ischemia tolerance; model for research, hope for clinical practice?

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12 December 2020

Neuron-specific transgene expression of Bcl-XL but not Bcl-2 genes reduced lesion size after permanent middle cerebral artery occlusion in mice

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12 December 2020

Mitochondrial intermembrane proteins in cell death

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12 December 2020

Do transient ischemic attacks have a neuroprotective effect?

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12 December 2020

Inflammation and glial responses in ischemic brain lesions.

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12 December 2020

Body temperature in acute stroke: relation to stroke severity, infarct size, mortality, and outcome

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12 December 2020

Stroke severity determines body temperature in acute stroke

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12 December 2020

Fever and infection early after ischemic stroke

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12 December 2020

Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury

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12 December 2020

Delayed effect of administration of COX-2 inhibitor in mice with acute cerebral ischemia

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12 December 2020

Desferrioxamine induces delayed tolerance against cerebral ischemia in vivo and in vitro

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12 December 2020

Aetiology of fever in patients with acute stroke.

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12 December 2020

Induction of hypoxia inducible factor 1 by oxygen glucose deprivation is attenuated by hypoxic preconditioning in rat cultured neurons.

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12 December 2020

Neuroprotective effects of gelsolin during murine stroke

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12 December 2020

Characterization of cortical depolarizations evoked in focal cerebral ischemia.

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12 December 2020

10.1023/B:MEBR.0000043966.46964.E6

Identifiers

DOI

1 reference

PubMed ID

15554412

Dimensions Publication ID

11 August 2017

0 references

1 reference

PubMed ID

15554412