(Q35956623)

English

Clodronate : a review of its use in the prevention of bone metastases and the management of skeletal complications associated with bone metastases in patients with breast cancer

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

1 reference

Europe PubMed Central

Clodronate : a review of its use in the prevention of bone metastases and the management of skeletal complications associated with bone metastases in patients with breast cancer (English)

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

author name string

Toni M Dando

1

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

Lynda R Wiseman

2

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

publication date

1 January 2004

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

21

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

14

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

949-962

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

https://scigraph.springernature.com/pub.10.2165/00002512-200421140-00005

0 references

Bisphosphonate Induced Growth Inhibition of Breast Cancer Cells is Augmented by p38 Inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Future directions in the treatment and prevention of bone metastases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clodronate kinetics and bioavailability

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bisphosphonates inhibit stromelysin-1 (MMP-3), matrix metalloelastase (MMP-12), collagenase-3 (MMP-13) and enamelysin (MMP-20), but not urokinase-type plasminogen activator, and diminish invasion and migration of human malignant and endothelial cell

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bisphosphonates inhibit prostate and breast carcinoma cell adhesion to unmineralized and mineralized bone extracellular matrices.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The absolute bioavailability of clodronate from two different oral doses

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Double-blind controlled trial of oral clodronate in patients with bone metastases from breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Randomized, placebo-controlled trial of clodronate in patients with primary operable breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adjuvant clodronate treatment does not reduce the frequency of skeletal metastases in node-positive breast cancer patients: 5-year results of a randomized controlled trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dosing regimens and main adverse events of bisphosphonates

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clodronate: a review of its use in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The use of zoledronic acid in the management of metastatic bone disease and hypercalcaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of MMP-9 (gelatinase B) in activated human monocyte/macrophages by two different types of bisphosphonates

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Double-blinded controlled study comparing clodronate versus placebo in patients with breast cancer bone metastases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction in new metastases in breast cancer with adjuvant clodronate treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extended safety profile of oral clodronate after long-term use in primary breast cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral clodronate in breast cancer patients with bone metastases: a randomized study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bisphosphonates and metastatic breast carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clodronate decreases the frequency of skeletal metastases in women with breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bisphosphonates as adjuvant treatment for breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bisphosphonates inhibit breast and prostate carcinoma cell invasion, an early event in the formation of bone metastases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitrogen-containing bisphosphonates induce apoptosis of Caco-2 cells in vitro by inhibiting the mevalonate pathway: a model of bisphosphonate-induced gastrointestinal toxicity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Does supportive pamidronate treatment prevent or delay the first manifestation of bone metastases in breast cancer patients?

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of osteolytic bone metastases in breast carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bisphosphonates suppress bone resorption by a direct effect on early osteoclast precursors without affecting the osteoclastogenic capacity of osteogenic cells: the role of protein geranylgeranylation in the action of nitrogen-containing bisphosphona

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bisphosphonate therapy for patients with breast carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osteonecrosis of the jaws associated with the use of bisphosphonates: a review of 63 cases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clodronate inhibits adrenocortical cell proliferation and P450c21 activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bisphosphonates induce apoptosis in human breast cancer cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of clodronate in patients with metastatic breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The clinical and cost considerations of bisphosphonates in preventing bone complications in patients with metastatic breast cancer or multiple myeloma

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bisphosphonates act directly on the osteoclast to induce caspase cleavage of mst1 kinase during apoptosis. A link between inhibition of the mevalonate pathway and regulation of an apoptosis-promoting kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Timing of food intake has a marked effect on the bioavailability of clodronate

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The present and future role of bisphosphonates in the management of patients with breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antitumor effects of bisphosphonates

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Zoledronic acid: an advance in tumour bone disease therapy and a new hope for osteoporosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cost analysis of secondary prophylaxis with oral clodronate versus pamidronate in metastatic breast cancer patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical and economic issues in the treatment of advanced breast cancer with bisphosphonates

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel approaches to the management of bone metastases

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of pharmacokinetics of clodronate after single and repeated doses

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The bisphosphonate pamidronate is a potent inhibitor of human osteosarcoma cell growth in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

American Society of Clinical Oncology 2003 update on the role of bisphosphonates and bone health issues in women with breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bisphosphonates induce breast cancer cell death in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The antineoplastic role of bisphosphonates: from basic research to clinical evidence.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bisphosphonates influence the proliferation and the maturation of normal human osteoblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/15554753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2165/00002512-200421140-00005

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

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