(Q35968979)

English

Genome-Wide Pharmacogenomic Study on Methadone Maintenance Treatment Identifies SNP rs17180299 and Multiple Haplotypes on CYP2B6, SPON1, and GSG1L Associated with Plasma Concentrations of Methadone R- and S-enantiomers in Heroin-Dependent Patients

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scholarly article

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Europe PubMed Central

PMC publication ID

11 August 2017

Genome-Wide Pharmacogenomic Study on Methadone Maintenance Treatment Identifies SNP rs17180299 and Multiple Haplotypes on CYP2B6, SPON1, and GSG1L Associated with Plasma Concentrations of Methadone R- and S-enantiomers in Heroin-Dependent Patients (English)

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

pharmacogenomics

1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

1

object named as

Hsin-Chou Yang

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Europe PubMed Central

11 August 2017

PMC publication ID

author name string

Shih-Kai Chu

2

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Chieh-Liang Huang

3

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Hsiang-Wei Kuo

4

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Sheng-Chang Wang

5

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Sheng-Wen Liu

6

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Ing-Kang Ho

7

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Yu-Li Liu

8

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

publication date

24 March 2016

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Europe PubMed Central

PMC publication ID

11 August 2017

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

12

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Europe PubMed Central

PMC publication ID

11 August 2017

3

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

e1005910

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

copyright license

Creative Commons Attribution 4.0 International

24 March 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Impact of ABCB1 and CYP2B6 genetic polymorphisms on methadone metabolism, dose and treatment response in patients with opioid addiction: a systematic review and meta-analysis

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Pharmacometric characterization of efavirenz developmental pharmacokinetics and pharmacogenetics in HIV-infected children

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DNA methylation age of human tissues and cell types

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Functional genetic polymorphisms in CYP2C19 gene in relation to cardiac side effects and treatment dose in a methadone maintenance cohort.

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CYP2B6 SNPs are associated with methadone dose required for effective treatment of opioid addiction

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Stereo-selective metabolism of methadone by human liver microsomes and cDNA-expressed cytochrome P450s: a reconciliation

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OPRM1 and CYP2B6 Gene Variants as Risk Factors in Methadone-Related Deaths

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Development of a method to measure methadone enantiomers and its metabolites without enantiomer standard compounds for the plasma of methadone maintenance patients

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CYP2B6 variants and plasma efavirenz concentrations during antiretroviral therapy in Port-au-Prince, Haiti

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Methadone maintenance therapy versus no opioid replacement therapy for opioid dependence

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A flexible and accurate genotype imputation method for the next generation of genome-wide association studies

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Methadone induces the expression of hepatic drug-metabolizing enzymes through the activation of pregnane X receptor and constitutive androstane receptor

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2 October 2017

Clinical pharmacology of methadone for pain

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2 October 2017

A second generation human haplotype map of over 3.1 million SNPs

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2 October 2017

PLINK: a tool set for whole-genome association and population-based linkage analyses

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2 October 2017

Cytochrome P450 enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells

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2 October 2017

Enantiomeric metabolic interactions and stereoselective human methadone metabolism

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2 October 2017

A note on exact tests of Hardy-Weinberg equilibrium

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2 October 2017

Heroin dependence.

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Substitution management in opioid dependence

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Methadone maintenance therapy versus no opioid replacement therapy for opioid dependence

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The structure of haplotype blocks in the human genome

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The economic costs of heroin addiction in the United States

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Contribution of CYP2B6 alleles in explaining extreme (S)-methadone plasma levels: a CYP2B6 gene resequencing study.

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Genetic polymorphisms in CYP3A4 are associated with withdrawal symptoms and adverse reactions in methadone maintenance patients.

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CYP2B6 polymorphisms influence the plasma concentration and clearance of the methadone S-enantiomer.

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Role of CYP2B6 in stereoselective human methadone metabolism

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CYP2B6 and OPRM1 gene variations predict methadone-related deaths

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Identifiers

10.1371/JOURNAL.PGEN.1005910

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

ResearchGate publication ID

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