(Q35982097)

English

Combined inhibition of PLC{gamma}-1 and c-Src abrogates epidermal growth factor receptor-mediated head and neck squamous cell carcinoma invasion

scientific article

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scholarly article

1 reference

Europe PubMed Central

11 August 2017

Combined inhibition of PLC{gamma}-1 and c-Src abrogates epidermal growth factor receptor-mediated head and neck squamous cell carcinoma invasion (English)

1 reference

Europe PubMed Central

11 August 2017

head and neck squamous cell carcinoma

1 reference

based on heuristic

inferred from title

Judith Klein-Seetharaman

6

object named as

Judith Klein-Seetharaman

0 references

object named as

Sufi M Thomas

9

0 references

object named as

Alan Wells

7

0 references

Jennifer Rubin Grandis

8

object named as

Jennifer R Grandis

1 reference

Europe PubMed Central

11 August 2017

author name string

Hiroshi Nozawa

1

1 reference

Europe PubMed Central

11 August 2017

Gina Howell

2

1 reference

Europe PubMed Central

11 August 2017

Shinsuke Suzuki

3

1 reference

Europe PubMed Central

11 August 2017

Qing Zhang

4

1 reference

Europe PubMed Central

11 August 2017

Yanjun Qi

5

1 reference

Europe PubMed Central

11 August 2017

language of work or name

0 references

publication date

1 July 2008

1 reference

Europe PubMed Central

11 August 2017

Clinical Cancer Research

1 reference

Europe PubMed Central

11 August 2017

14

1 reference

Europe PubMed Central

11 August 2017

13

1 reference

Europe PubMed Central

11 August 2017

4336-4344

1 reference

Europe PubMed Central

11 August 2017

Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358699

2 October 2017

N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5- (tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine, a novel, highly selective, orally available, dual-specific c-Src/Abl kinase inhibitor

1 reference

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2 October 2017

Reverse phase protein array: validation of a novel proteomic technology and utility for analysis of primary leukemia specimens and hematopoietic stem cells

1 reference

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2 October 2017

Elevated Src activity promotes cellular invasion and motility in tamoxifen resistant breast cancer cells.

1 reference

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2 October 2017

Dasatinib (BMS-354825) tyrosine kinase inhibitor suppresses invasion and induces cell cycle arrest and apoptosis of head and neck squamous cell carcinoma and non-small cell lung cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358699

2 October 2017

SRC family kinases mediate epidermal growth factor receptor ligand cleavage, proliferation, and invasion of head and neck cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358699

2 October 2017

SH2 and SH3 domains

1 reference

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2 October 2017

The C terminus of c-Src inhibits breast tumor cell growth by a kinase-independent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358699

2 October 2017

The epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 (Iressa) suppresses c-Src and Pak1 pathways and invasiveness of human cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358699

2 October 2017

Src family kinases in tumor progression and metastasis

1 reference

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2 October 2017

Src kinases mediate STAT growth pathways in squamous cell carcinoma of the head and neck

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358699

2 October 2017

GeneMerge—post-genomic analysis, data mining, and hypothesis testing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358699

2 October 2017

Epidermal growth factor stimulation can substitute for c-Src overexpression in promoting breast carcinoma invasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358699

2 October 2017

Src-dependent phosphorylation of the epidermal growth factor receptor on tyrosine 845 is required for zinc-induced Ras activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358699

2 October 2017

Src kinase contributes to the metastatic spread of carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358699

2 October 2017

Structure, regulation, and function of phospholipase C isozymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358699

2 October 2017

SH2 domains, interaction modules and cellular wiring

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358699

2 October 2017

The epidermal growth factor receptor regulates interaction of the human DF3/MUC1 carcinoma antigen with c-Src and beta-catenin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358699

2 October 2017

The versatility and universality of calcium signalling

1 reference

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2 October 2017

Regulation of phosphoinositide-specific phospholipase C

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358699

2 October 2017

Structure, function, and control of phosphoinositide-specific phospholipase C

1 reference

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2 October 2017

Gene ontology: tool for the unification of biology

1 reference

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2 October 2017

The role of individual SH2 domains in mediating association of phospholipase C-gamma1 with the activated EGF receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358699

2 October 2017

A role for phospholipase C-gamma-mediated signaling in tumor cell invasion

1 reference

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2 October 2017

Take your partners, please--signal diversification by the erbB family of receptor tyrosine kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358699

2 October 2017

c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358699

2 October 2017

Structures of Src-family tyrosine kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358699

2 October 2017

1,25 dihydroxyvitamin D3 stimulates phospholipase C-gamma in rat colonocytes: role of c-Src in PLC-gamma activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358699

2 October 2017

Src family protein tyrosine kinases: cooperating with growth factor and adhesion signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358699

2 October 2017

c-Src protein expression is increased in human breast cancer. An immunohistochemical and biochemical analysis

1 reference

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A neu acquaintance for erbB3 and erbB4: a role for receptor heterodimerization in growth signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358699

2 October 2017

Src phosphorylation of the epidermal growth factor receptor at novel sites mediates receptor interaction with Src and P85 alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358699

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In vitro tyrosine phosphorylation of PLC-gamma 1 and PLC-gamma 2 by src-family protein tyrosine kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358699

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Potentiation of epidermal growth factor receptor-mediated oncogenesis by c-Src: implications for the etiology of multiple human cancers

1 reference

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Involvement of pp60c-src with two major signaling pathways in human breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358699

2 October 2017

pp60c-src activation in human colon carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358699

2 October 2017

A site of tyrosine phosphorylation in the C terminus of the epidermal growth factor receptor is required to activate phospholipase C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358699

2 October 2017

Characterization of protein tyrosine kinases from human breast cancer: involvement of the c-src oncogene product.

1 reference

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Type IV collagen stimulates an increase in intracellular calcium. Potential role in tumor cell motility

1 reference

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Individual epidermal growth factor receptor autophosphorylation sites do not stringently define association motifs for several SH2-containing proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358699

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Expression of pp60c-src protein kinase in adult and fetal human tissue: high activities in some sarcomas and mammary carcinomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358699

11 July 2018

Low incidence of mutations in EGFR kinase domain in Caucasian patients with head and neck squamous cell carcinoma

1 reference

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24 September 2018

Epidermal growth factor receptor-stimulated activation of phospholipase Cgamma-1 promotes invasion of head and neck squamous cell carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3358699

24 September 2018

Mitogenic effects of gastrin-releasing peptide in head and neck squamous cancer cells are mediated by activation of the epidermal growth factor receptor.

1 reference

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Elevated levels of transforming growth factor alpha and epidermal growth factor receptor messenger RNA are early markers of carcinogenesis in head and neck cancer.

1 reference

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24 September 2018

Overexpression of c-Src in areas of hyperproliferation in head and neck cancer, premalignant lesions and benign mucosal disorders

1 reference

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12 December 2020

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Electroporation of pp60c−srcAntibodies Inhibits the Angiotensin II Activation of Phospholipase C-γ1 in Rat Aortic Smooth Muscle Cells

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https://pubmed.ncbi.nlm.nih.gov/18594017

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Motility is rate-limiting for invasion of bladder carcinoma cell lines

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https://pubmed.ncbi.nlm.nih.gov/18594017

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Epidermal growth factor receptor-mediated motility in fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/18594017

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Analysis of pp60c-src protein kinase activity in human tumor cell lines and tissues

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Expression of integrins in squamous cell carcinoma of the oral cavity. Correlations with tumor invasion and metastasis

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https://pubmed.ncbi.nlm.nih.gov/18594017

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Identifiers

10.1158/1078-0432.CCR-07-4857

1 reference

Europe PubMed Central

11 August 2017

1 reference

Europe PubMed Central

11 August 2017

1 reference

Europe PubMed Central

11 August 2017

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