(Q35989852)

English

The new multicomponent vaccine against meningococcal serogroup B, 4CMenB: immunological, functional and structural characterization of the antigens

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scholarly article

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Europe PubMed Central

PMC publication ID

11 August 2017

The new multicomponent vaccine against meningococcal serogroup B, 4CMenB: immunological, functional and structural characterization of the antigens (English)

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

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based on heuristic

inferred from title

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based on heuristic

inferred from title

5

object named as

Rino Rappuoli

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

1

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Davide Serruto

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

author name string

Matthew J Bottomley

2

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Sanjay Ram

3

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Europe PubMed Central

PMC publication ID

11 August 2017

Marzia M Giuliani

4

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Europe PubMed Central

PMC publication ID

11 August 2017

language of work or name

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publication date

1 May 2012

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Europe PubMed Central

PMC publication ID

11 August 2017

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Europe PubMed Central

PMC publication ID

11 August 2017

30 Suppl 2

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Europe PubMed Central

PMC publication ID

11 August 2017

B87-97

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Europe PubMed Central

PMC publication ID

11 August 2017

Combined roles of human IgG subclass, alternative complement pathway activation, and epitope density in the bactericidal activity of antibodies to meningococcal factor h binding protein

1 reference

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1 reference

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Rational design of a meningococcal antigen inducing broad protective immunity

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Complement-mediated bactericidal activity of anti-factor H binding protein monoclonal antibodies against the meningococcus relies upon blocking factor H binding

1 reference

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New frontiers in meningococcal vaccines

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Immunogenicity of a meningococcal native outer membrane vesicle vaccine with attenuated endotoxin and over-expressed factor H binding protein in infant rhesus monkeys.

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A critical threshold of meningococcal factor H binding protein expression is required for increased breadth of protective antibodies elicited by native outer membrane vesicle vaccines

1 reference

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Cooperative serum bactericidal activity between human antibodies to meningococcal factor H binding protein and neisserial heparin binding antigen.

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A phase 1 study of a meningococcal native outer membrane vesicle vaccine made from a group B strain with deleted lpxL1 and synX, over-expressed factor H binding protein, two PorAs and stabilized OpcA expression.

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Characterization of diverse subvariants of the meningococcal factor H (fH) binding protein for their ability to bind fH, to mediate serum resistance, and to induce bactericidal antibodies

1 reference

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Infections of People with Complement Deficiencies and Patients Who Have Undergone Splenectomy

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Genetic shifts of Neisseria meningitidis serogroup B antigens and the quest for a broadly cross-protective vaccine

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Advances in the development of vaccines against Neisseria meningitidis

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Characterization of fHbp, nhba (gna2132), nadA, porA, and sequence type in group B meningococcal case isolates collected in England and Wales during January 2008 and potential coverage of an investigational group B meningococcal vaccine

1 reference

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The epidemiology of meningococcal disease and the impact of vaccines

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Neisseria meningitidis GNA2132, a heparin-binding protein that induces protective immunity in humans

1 reference

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Serogroup B meningococcal vaccines-an unfinished story

1 reference

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A novel phase variation mechanism in the meningococcus driven by a ligand-responsive repressor and differential spacing of distal promoter elements

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Expression of factor H binding protein of meningococcus responds to oxygen limitation through a dedicated FNR-regulated promoter.

1 reference

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Mechanisms of avoidance of host immunity by Neisseria meningitidis and its effect on vaccine development

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Properties and clinical performance of vaccines containing outer membrane vesicles from Neisseria meningitidis

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Biology and pathogenesis of the evolutionarily successful, obligate human bacterium Neisseria meningitidis

1 reference

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Meningococcal carriage and disease--population biology and evolution

1 reference

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Distribution and genetic variability of three vaccine components in a panel of strains representative of the diversity of serogroup B meningococcus

1 reference

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Pathogenic neisseriae: surface modulation, pathogenesis and infection control

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Neisseria meningitidis recruits factor H using protein mimicry of host carbohydrates

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Genome-based approaches to develop vaccines against bacterial pathogens

1 reference

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Solution Structure of the Factor H-binding Protein, a Survival Factor and Protective Antigen of Neisseria meningitidis

1 reference

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Structural Basis for the Immunogenic Properties of the Meningococcal Vaccine Candidate LP2086

1 reference

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Epitope mapping of a bactericidal monoclonal antibody against the factor H binding protein of Neisseria meningitidis.

1 reference

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1 reference

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Fine antigenic specificity and cooperative bactericidal activity of monoclonal antibodies directed at the meningococcal vaccine candidate factor h-binding protein

1 reference

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1 reference

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Genetics and evolution of Neisseria meningitidis: importance for the epidemiology of meningococcal disease

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Bactericidal antibody responses induced by meningococcal recombinant chimeric factor H-binding protein vaccines

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Vaccine-induced opsonophagocytic immunity to Neisseria meningitidis group B.

1 reference

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Immunogenicity of a tetravalent meningococcal glycoconjugate vaccine in infants: a randomized controlled trial.

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Interactions between Neisseria meningitidis and the complement system.

1 reference

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Three cases of invasive meningococcal disease caused by a capsule null locus strain circulating among healthy carriers in Burkina Faso

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Conquering the meningococcus

1 reference

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A universal vaccine for serogroup B meningococcus

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The meningococcal vaccine candidate GNA1870 binds the complement regulatory protein factor H and enhances serum resistance

1 reference

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Trimeric autotransporter adhesins: variable structure, common function

1 reference

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Trimeric autotransporters: a distinct subfamily of autotransporter proteins

1 reference

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Microsatellite instability regulates transcription factor binding and gene expression

1 reference

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The region comprising amino acids 100 to 255 of Neisseria meningitidis lipoprotein GNA 1870 elicits bactericidal antibodies

1 reference

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2 October 2017

Neisseria meningitidis NadA is a new invasin which promotes bacterial adhesion to and penetration into human epithelial cells.

1 reference

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Bacteremia in an immunocompromised patient caused by a commensal Neisseria meningitidis strain harboring the capsule null locus (cnl).

1 reference

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2 October 2017

NadA diversity and carriage in Neisseria meningitidis

1 reference

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Vaccine potential of the Neisseria meningitidis 2086 lipoprotein

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1 reference

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Vaccination against Neisseria meningitidis using three variants of the lipoprotein GNA1870

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NadA, a novel vaccine candidate of Neisseria meningitidis

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2 October 2017

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Human immunity to the meningococcus. II. Development of natural immunity

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Human heat shock protein (Hsp) 90 interferes with Neisseria meningitidis adhesin A (NadA)-mediated adhesion and invasion

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24 September 2018

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24 September 2018

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24 September 2018

Complement-dependent synergistic bactericidal activity of antibodies against factor H-binding protein, a sparsely distributed meningococcal vaccine antigen

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24 September 2018

Neisseria meningitidis group B correlates of protection and assay standardization--international meeting report Emory University, Atlanta, Georgia, United States, 16-17 March 2005.

1 reference

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24 September 2018

Antibody to genome-derived neisserial antigen 2132, a Neisseria meningitidis candidate vaccine, confers protection against bacteremia in the absence of complement-mediated bactericidal activity

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24 September 2018

Genetic Analysis of Meningococci Carried by Children and Young Adults

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14 November 2018

Rapid and Fatal Meningococcal Disease Due to a Strain of Neisseria meningitidis Containing the Capsule Null Locus

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14 November 2018

Meningococcal Meningitis: Unprecedented Incidence of Serogroup X--Related Cases in 2006 in Niger

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7 January 2021

Efficacy, safety, and immunogenicity of a meningococcal group B (15:P1.3) outer membrane protein vaccine in Iquique, Chile. Chilean National Committee for Meningococcal Disease

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7 January 2021

MeNZB: a safe and highly immunogenic tailor-made vaccine against the New Zealand Neisseria meningitidis serogroup B disease epidemic strain

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7 January 2021

Production, characterization and control of a Neisseria meningitidis hexavalent class 1 outer membrane protein containing vesicle vaccine

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7 January 2021

A phase 1 study of a group B meningococcal native outer membrane vesicle vaccine made from a strain with deleted lpxL2 and synX and stable expression of opcA

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7 January 2021

Improved immunogenicity of a H44/76 group B outer membrane vesicle vaccine with over-expressed genome-derived Neisserial antigen 1870

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7 January 2021

An experimental outer membrane vesicle vaccine from N. meningitidis serogroup B strains that induces serum bactericidal activity to multiple serogroups

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7 January 2021

Design and evaluation in mice of a broadly protective meningococcal group B native outer membrane vesicle vaccine

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7 January 2021

Functional significance of factor H binding to Neisseria meningitidis

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7 January 2021

Influence of sequence variability on bactericidal activity sera induced by Factor H binding protein variant 1.1.

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7 January 2021

Identification of multiple sites of interaction between heparin and the complement system

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7 January 2021

Prevalence and sequence variations of the genes encoding the five antigens included in the novel 5CVMB vaccine covering group B meningococcal disease

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7 January 2021

Putative vaccine antigens from Neisseria meningitidis recognized by serum antibodies of young children convalescing after meningococcal disease

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7 January 2021

Prevalence and genetic diversity of candidate vaccine antigens among invasive Neisseria meningitidis isolates in the United States

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7 January 2021

Multicenter, open-label, randomized phase II controlled trial of an investigational recombinant Meningococcal serogroup B vaccine with and without outer membrane vesicles, administered in infancy.

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7 January 2021

Early clinical experience with a candidate meningococcal B recombinant vaccine (rMenB) in healthy adults

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7 January 2021

An IgG monoclonal antibody to group B meningococci cross-reacts with developmentally regulated polysialic acid units of glycoproteins in neural and extraneural tissues

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunogenicity of 2 Investigational Serogroup B Meningococcal Vaccines in the First Year of Life

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Licensure of a meningococcal conjugate vaccine for children aged 2 through 10 years and updated booster dose guidance for adolescents and other persons at increased risk for meningococcal disease--Advisory Committee on Immunization Practices (ACIP),

1 reference

https://pubmed.ncbi.nlm.nih.gov/22607904

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.VACCINE.2012.01.033

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

ResearchGate publication ID

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