(Q35990000)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26240322%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

title

Consecutive radical S-adenosylmethionine methylations form the ethyl side chain in thienamycin biosynthesis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26240322%20AND%20SRC:MED&resulttype=core&format=json

carbapenem biosynthesis intermediate 1

20 February 2020

main subject

1 reference

ChEBI release 2020-05-28

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26240322%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Evan P Lloyd

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26240322%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Andrew R Buller

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26240322%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

author name string

Kristos A Moshos

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26240322%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Tyler L Grove

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26240322%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Anthony J Blaszczyk

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26240322%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Squire J Booker

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26240322%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Craig A Townsend

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26240322%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

language of work or name

English

0 references

publication date

3 August 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26240322%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

20 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26240322%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

volume

112

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26240322%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

page(s)

10354-10358

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26240322%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

issue

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26240322%20AND%20SRC:MED&resulttype=core&format=json

Delineating the biosynthesis of gentamicin x2, the common precursor of the gentamicin C antibiotic complex

20 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4547291

Mechanistic diversity of radical S-adenosylmethionine (SAM)-dependent methylation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4547291

Radical S-adenosylmethionine enzymes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4547291

Identification and characterization of the carbapenem MM 4550 and its gene cluster in Streptomyces argenteolus ATCC 11009.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4547291

Initial characterization of Fom3 from Streptomyces wedmorensis: The methyltransferase in fosfomycin biosynthesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4547291

GenK-catalyzed C-6' methylation in the biosynthesis of gentamicin: isolation and characterization of a cobalamin-dependent radical SAM enzyme.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4547291

Metagenome mining reveals polytheonamides as posttranslationally modified ribosomal peptides

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4547291

Radical-mediated enzymatic methylation: a tale of two SAMS

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4547291

Cfr and RlmN contain a single [4Fe-4S] cluster, which directs two distinct reactivities for S-adenosylmethionine: methyl transfer by SN2 displacement and radical generation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4547291

Definition of the common and divergent steps in carbapenem β-lactam antibiotic biosynthesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4547291

RlmN and Cfr are radical SAM enzymes involved in methylation of ribosomal RNA

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4547291

Escherichia coli allows efficient modular incorporation of newly isolated quinomycin biosynthetic enzyme into echinomycin biosynthetic pathway for rational design and synthesis of potent antibiotic unnatural natural product

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4547291

Four enzymes define the incorporation of coenzyme A in thienamycin biosynthesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4547291

Regulation and biosynthesis of carbapenem antibiotics in bacteria.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4547291

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4547291

Spectroscopic characterization and mechanistic investigation of P-methyl transfer by a radical SAM enzyme from the marine bacterium Shewanella denitrificans OS217.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4547291

Mutational analysis of the thienamycin biosynthetic gene cluster from Streptomyces cattleya

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4547291

Studies on the OA-6129 group of antibiotics, new carbapenem compounds. I. Taxonomy, isolation and physical properties.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4547291

Thiostrepton tryptophan methyltransferase expands the chemistry of radical SAM enzymes.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4547291

RlmN and AtsB as models for the overproduction and characterization of radical SAM proteins.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4547291

Biosynthetic studies and genetic engineering of pactamycin analogs with improved selectivity toward malarial parasites.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4547291

Measurement of energetics of conformational change in cobalamin-dependent methionine synthase.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4547291

Synthesis of (3S,5R)-carbapenam-3-carboxylic acid and its role in carbapenem biosynthesis and the stereoinversion problem

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4547291

Evidence for the formation of a linear [3Fe-4S] cluster in partially unfolded aconitase

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4547291

Stereochemistry of methylation in thienamycin biosynthesis: example of a methyl transfer from methionine with retention of configuration

24 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1508615112

Semi-micro methods for analysis of labile sulfide and of labile sulfide plus sulfane sulfur in unusually stable iron-sulfur proteins

21 January 2018

1 reference

12 December 2020

The Radical SAM Superfamily

1 reference

12 December 2020

Chemical-ionization mass spectrometry of beta-lactam antibiotics

1 reference

12 December 2020

Micro methods for the quantitative determination of iron and copper in biological material

1 reference

12 December 2020

Biosynthesis of the beta-lactam antibiotic, thienamycin, by Streptomyces cattleya

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1508615112

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26240322%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26240322%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26240322%20AND%20SRC:MED&resulttype=core&format=json