(Q37228577)

English

GenK-catalyzed C-6' methylation in the biosynthesis of gentamicin: isolation and characterization of a cobalamin-dependent radical SAM enzyme.

scientific article published on 21 May 2013

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scholarly article

1 reference

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1 March 2020

GenK-catalyzed C-6' methylation in the biosynthesis of gentamicin: isolation and characterization of a cobalamin-dependent radical SAM enzyme (English)

1 reference

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1 March 2020

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Yasushi Ogasawara

3

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1 March 2020

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Hak Joong Kim

1

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1 March 2020

Reid M McCarty

2

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1 March 2020

Yung-nan Liu

4

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1 March 2020

Steven O Mansoorabadi

5

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1 March 2020

Jake LeVieux

6

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1 March 2020

Hung-wen Liu

7

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1 March 2020

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21 May 2013

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1 March 2020

Journal of the American Chemical Society

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1 March 2020

135

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1 March 2020

8093-8096

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1 March 2020

22

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1 March 2020

EPR-kinetic isotope effect study of the mechanism of radical-mediated dehydrogenation of an alcohol by the radical SAM enzyme DesII.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3796153

6 September 2017

Radical-mediated enzymatic methylation: a tale of two SAMS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3796153

6 September 2017

In vitro phosphinate methylation by PhpK from Kitasatospora phosalacinea

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3796153

6 September 2017

Mechanistic studies of the radical S-adenosyl-L-methionine enzyme DesII: EPR characterization of a radical intermediate generated during its catalyzed dehydrogenation of TDP-D-quinovose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3796153

6 September 2017

Structure and mechanism of enzymes involved in biosynthesis and breakdown of the phosphonates fosfomycin, dehydrophos, and phosphinothricin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3796153

6 September 2017

Stoichiometry of the redox neutral deamination and oxidative dehydrogenation reactions catalyzed by the radical SAM enzyme DesII.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3796153

6 September 2017

Radical and electron recycling in catalysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3796153

6 September 2017

Anaerobic functionalization of unactivated C-H bonds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3796153

6 September 2017

Cobalamin-dependent and cobamide-dependent methyltransferases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3796153

6 September 2017

Genetic dissection of the biosynthetic route to gentamicin A2 by heterologous expression of its minimal gene set.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3796153

6 September 2017

Chlorophyll biosynthesis in bacteria: the origins of structural and functional diversity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3796153

6 September 2017

Gene cluster in Micromonospora echinospora ATCC15835 for the biosynthesis of the gentamicin C complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3796153

6 September 2017

Radical SAM, a novel protein superfamily linking unresolved steps in familiar biosynthetic pathways with radical mechanisms: functional characterization using new analysis and information visualization methods

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3796153

6 September 2017

Anaerobic chlorophyll isocyclic ring formation in Rhodobacter capsulatus requires a cobalamin cofactor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3796153

6 September 2017

Antibiotic from Micromonospora

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3796153

6 September 2017

Identification of gntK, a gene required for the methylation of purpurosamine C-6' in gentamicin biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3796153

26 June 2018

Studies on the biosynthesis of fosfomycin. 4. The biosynthetic origin of the methyl group of fosfomycin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3796153

26 June 2018

Biotransformation, a new approach to aminoglycoside biosynthesis: II. Gentamicin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3796153

26 June 2018

Thiostrepton tryptophan methyltransferase expands the chemistry of radical SAM enzymes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3796153

3 September 2018

An allylic ketyl radical intermediate in clostridial amino-acid fermentation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3796153

3 September 2018

GENTAMICIN, A NEW ANTIBIOTIC COMPLEX FROM MICROMONOSPORA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3796153

3 September 2018

Cobalamin-dependent methyltransferases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3796153

3 September 2018

Studies on the biosynthesis of bialaphos (SF-1293) 12. C-P bond formation mechanism of bialaphos: Discovery of a P-methylation enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/23679096

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New insight into the mechanism of methyl transfer during the biosynthesis of fosfomycin

1 reference

https://pubmed.ncbi.nlm.nih.gov/23679096

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Radical SAM Superfamily

1 reference

https://pubmed.ncbi.nlm.nih.gov/23679096

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cobalamin reduction by dithionite. Evidence for the formation of a six-coordinate cobalamin(II) complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/23679096

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/JA312641F

1 reference

Europe PubMed Central

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1 March 2020

release_jq5p2kjbejh4dd4gwsjs7gjx5a

1 reference

https://api.fatcat.wiki/v0/release/jq5p2kjbejh4dd4gwsjs7gjx5a

24 November 2022

based on heuristic

mapped directly with Wikidata item

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Europe PubMed Central

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1 March 2020

1 reference

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1 March 2020

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