(Q35991812)

English

Klotho-beta overexpression as a novel target for suppressing proliferation and fibroblast growth factor receptor-4 signaling in hepatocellular carcinoma

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scholarly article

1 reference

Europe PubMed Central

11 August 2017

Klotho-beta overexpression as a novel target for suppressing proliferation and fibroblast growth factor receptor-4 signaling in hepatocellular carcinoma (English)

1 reference

Europe PubMed Central

11 August 2017

1 reference

based on heuristic

inferred from title

5

object named as

Seng Gee Lim

1 reference

Europe PubMed Central

11 August 2017

author name string

Weijie Poh

1

1 reference

Europe PubMed Central

11 August 2017

Winnie Wong

2

1 reference

Europe PubMed Central

11 August 2017

Huimin Ong

3

1 reference

Europe PubMed Central

11 August 2017

Myat Oo Aung

4

1 reference

Europe PubMed Central

11 August 2017

Boon Tin Chua

6

1 reference

Europe PubMed Central

11 August 2017

Han Kiat Ho

7

1 reference

Europe PubMed Central

11 August 2017

publication date

23 March 2012

1 reference

Europe PubMed Central

11 August 2017

Molecular Cancer

1 reference

Europe PubMed Central

11 August 2017

11

1 reference

Europe PubMed Central

11 August 2017

14

1 reference

Europe PubMed Central

11 August 2017

https://scigraph.springernature.com/pub.10.1186/1476-4598-11-14

0 references

FGF19 regulates cell proliferation, glucose and bile acid metabolism via FGFR4-dependent and independent pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361496

2 October 2017

Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361496

2 October 2017

Metabolic regulator betaKlotho interacts with fibroblast growth factor receptor 4 (FGFR4) to induce apoptosis and inhibit tumor cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361496

2 October 2017

The AC133 epitope, but not the CD133 protein, is lost upon cancer stem cell differentiation

1 reference

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2 October 2017

FGF19-induced hepatocyte proliferation is mediated through FGFR4 activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361496

2 October 2017

Cancer stem/progenitor cells are highly enriched in CD133+CD44+ population in hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361496

2 October 2017

Molecular targeted therapies in hepatocellular carcinoma

1 reference

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Sorafenib in advanced hepatocellular carcinoma

1 reference

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2 October 2017

CD133+ HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway.

1 reference

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2 October 2017

Human hepatic stem cells from fetal and postnatal donors

1 reference

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2 October 2017

Liver-specific activities of FGF19 require Klotho beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361496

2 October 2017

Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21

1 reference

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2 October 2017

Identification and characterization of tumorigenic liver cancer stem/progenitor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361496

2 October 2017

BetaKlotho is required for metabolic activity of fibroblast growth factor 21

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361496

2 October 2017

A molecular signature to discriminate dysplastic nodules from early hepatocellular carcinoma in HCV cirrhosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361496

2 October 2017

Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361496

2 October 2017

Impaired negative feedback suppression of bile acid synthesis in mice lacking betaKlotho

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361496

2 October 2017

Hepatocellular carcinoma: molecular pathways and new therapeutic targets.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361496

2 October 2017

Gene expression patterns in human liver cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361496

2 October 2017

A mouse model of hepatocellular carcinoma: ectopic expression of fibroblast growth factor 19 in skeletal muscle of transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361496

2 October 2017

Elevated cholesterol metabolism and bile acid synthesis in mice lacking membrane tyrosine kinase receptor FGFR4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361496

2 October 2017

Specificity for fibroblast growth factors determined by heparan sulfate in a binary complex with the receptor kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361496

2 October 2017

Cellular aspects of alpha-fetoprotein reexpression in tumors

1 reference

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2 October 2017

Treatment of hepatocellular carcinoma: a systematic review of randomized controlled trials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361496

2 October 2017

PI3K: downstream AKTion blocks apoptosis

1 reference

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2 October 2017

Phosphorylation of c-jun mediated by MAP kinases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361496

2 October 2017

Resident hepatocyte fibroblast growth factor receptor 4 limits hepatocarcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3361496

11 July 2018

Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning

1 reference

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11 July 2018

SK HEP-1: a human cell line of endothelial origin

1 reference

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11 July 2018

Fibroblast growth factor receptor 4 regulates proliferation, anti-apoptosis and alpha-fetoprotein secretion during hepatocellular carcinoma progression and represents a potential target for therapeutic intervention

1 reference

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23 September 2018

Activation of the ERK and AKT signalling pathway predicts poor prognosis in hepatocellular carcinoma and ERK activation in cancer tissue is associated with hepatitis C virus infection

1 reference

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23 September 2018

Hepatic progenitor cells, stem cells, and AFP expression in models of liver injury.

1 reference

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23 September 2018

Forced expression of hepatocyte-specific fibroblast growth factor 21 delays initiation of chemically induced hepatocarcinogenesis.

1 reference

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23 September 2018

Involvement of the FGFR4 Arg388 allele in head and neck squamous cell carcinoma

1 reference

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23 September 2018

Cancer progression and tumor cell motility are associated with the FGFR4 Arg(388) allele

1 reference

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23 September 2018

Identifiers

10.1186/1476-4598-11-14

1 reference

Europe PubMed Central

11 August 2017

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1 reference

Europe PubMed Central

11 August 2017

1 reference

Europe PubMed Central

11 August 2017

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