(Q35993236)

11 August 2017

1 reference

title

Defensin deficiency, intestinal microbes, and the clinical phenotypes of Crohn's disease (English)

1 reference

11 August 2017

0 references

1

Jan Wehkamp

1 reference

11 August 2017

Michael Schmid

2

1 reference

PubMed ID

15618294

11 August 2017

Klaus Fellermann

series ordinal

3

1 reference

PubMed ID

15618294

11 August 2017

Eduard F Stange

series ordinal

4

1 reference

11 August 2017

23 December 2004

1 reference

Journal of Leukocyte Biology

11 August 2017

1 reference

11 August 2017

77

1 reference

11 August 2017

460-465

1 reference

11 August 2017

4

1 reference

Crohn's disease: a defensin deficiency syndrome?

11 August 2017

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Role of infections in the manifestation or reactivation of inflammatory bowel diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Expression of NOD2 in Paneth cells: a possible link to Crohn's ileitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Crohn's disease and the NOD2 gene: a role for paneth cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

TNF-alpha and IFN-gamma regulate the expression of the NOD2 (CARD15) gene in human intestinal epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Antimicrobial peptides as mediators of epithelial host defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Changes in the bacterial flora of the neoterminal ileum after ileocolonic resection for Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Mucosal flora in inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn’s disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Enhanced Escherichia coli adherence and invasion in Crohn's disease and colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

T cell specificity and cross reactivity towards enterobacteria, bacteroides, bifidobacterium, and antigens from resident intestinal flora in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

A peptide antibiotic from human skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Isolation and characterization of human beta -defensin-3, a novel human inducible peptide antibiotic

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Antibiotic peptides as mediators of innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Defensins: antimicrobial peptides of innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Widespread expression of beta-defensin hBD-1 in human secretory glands and epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Inducible expression of an antibiotic peptide gene in lipopolysaccharide-challenged tracheal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Toll-like receptor 4-dependent activation of dendritic cells by beta-defensin 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Antimicrobial peptides in innate immunity of the human intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

"For whom the bell tolls!" -- innate defense mechanisms and survival strategies of the intestinal epithelium against lumenal pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

NF-kappaB- and AP-1-mediated induction of human beta defensin-2 in intestinal epithelial cells by Escherichia coli Nissle 1917: a novel effect of a probiotic bacterium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

By IL-1 signaling, monocyte-derived cells dramatically enhance the epidermal antimicrobial response to lipopolysaccharide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Inducible and constitutive beta-defensins are differentially expressed in Crohn's disease and ulcerative colitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Defensin pattern in chronic gastritis: HBD-2 is differentially expressed with respect to Helicobacter pylori status.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Paneth cell trypsin is the processing enzyme for human defensin-5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Degranulation of paneth cells via toll-like receptor 9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Enteric salmonella infection inhibits Paneth cell antimicrobial peptide expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Expression of antimicrobial neutrophil defensins in epithelial cells of active inflammatory bowel disease mucosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Human defensin 5 is stored in precursor form in normal Paneth cells and is expressed by some villous epithelial cells and by metaplastic Paneth cells in the colon in inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Innate immunity and colonic inflammation: enhanced expression of epithelial alpha-defensins

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Antimicrobial peptides in the first line defence of human colon mucosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Rationale for probiotic and antibiotic treatment strategies in inflammatory bowel diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Non-pathogenic Escherichia coli versus mesalazine for the treatment of ulcerative colitis: a randomised trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Effect of probiotic strains on interleukin 8 production by HT29/19A cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Functional modulation of enterocytes by gram-positive and gram-negative microorganisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Deficient host-bacteria interactions in inflammatory bowel disease? The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn's disease and ulcerative colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

Polymorphisms of the lipopolysaccharide-signaling complex in inflammatory bowel disease: association of a mutation in the Toll-like receptor 4 gene with ulcerative colitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0904543

21 January 2018

Identifiers

DOI

10.1189/JLB.0904543

1 reference

11 August 2017

1 reference

PubMed ID

15618294