(Q35994069)

11 August 2017

P2X7 receptor-mediated purinergic signaling promotes liver injury in acetaminophen hepatotoxicity in mice (English)

1 reference

11 August 2017

1 reference

1 reference

Rafaz Hoque

1

1 reference

11 August 2017

Muhammed Adnan Sohail

2

1 reference

11 August 2017

Steven Salhanick

3

1 reference

11 August 2017

Ahsan F Malik

4

1 reference

11 August 2017

Ayaz Ghani

5

1 reference

11 August 2017

Simon C Robson

6

1 reference

11 August 2017

Wajahat Z Mehal

7

1 reference

11 August 2017

1 March 2012

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American Journal of Physiology - Gastrointestinal and Liver Physiology

11 August 2017

1 reference

11 August 2017

302

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11 August 2017

10

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11 August 2017

G1171-9

1 reference

TLR9 and the NLRP3 inflammasome link acinar cell death with inflammation in acute pancreatitis

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362096

Role of the Nalp3 inflammasome in acetaminophen-induced sterile inflammation and liver injury

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362096

Intravascular danger signals guide neutrophils to sites of sterile inflammation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362096

The role of damage associated molecular pattern molecules in acetaminophen-induced liver injury in mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362096

Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362096

Sensing pathogens and danger signals by the inflammasome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362096

Acetaminophen-induced hepatotoxicity in mice is dependent on Tlr9 and the Nalp3 inflammasome.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362096

Regulated catalysis of extracellular nucleotides by vascular CD39/ENTPD1 is required for liver regeneration

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362096

The E-NTPDase family of ectonucleotidases: Structure function relationships and pathophysiological significance

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362096

The role of purinergic signaling in the liver and in transplantation: effects of extracellular nucleotides on hepatic graft vascular injury, rejection and metabolism

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362096

Role of inflammation in the mechanism of acetaminophen-induced hepatotoxicity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362096

Role of innate immunity in acetaminophen-induced hepatotoxicity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362096

Acetaminophen-induced acute liver failure: results of a United States multicenter, prospective study

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362096

Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362096

Mechanisms of caspase-1 activation by P2X7 receptor-mediated K+ release.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362096

Cytokine-Induced Inflammatory Liver Injuries

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362096

Purinergic signaling and vascular cell proliferation and death

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362096

Role of macrophages and inflammatory mediators in chemically induced toxicity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362096

Altered cytokine production in mice lacking P2X(7) receptors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362096

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362096

Extracellular ATP is a danger signal activating P2X7 receptor in lung inflammation and fibrosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362096

NAD+ and ATP released from injured cells induce P2X7-dependent shedding of CD62L and externalization of phosphatidylserine by murine T cells

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362096

Isolation of mouse intrahepatic lymphocytes.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362096

Neutrophil depletion protects against murine acetaminophen hepatotoxicity

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362096

Opposite roles of neutrophils and macrophages in the pathogenesis of acetaminophen-induced acute liver injury.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362096

Innate immune system plays a critical role in determining the progression and severity of acetaminophen hepatotoxicity

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362096

Acetaminophen hepatoxicity: what do we know, what don't we know, and what do we do next?

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362096

NAD-induced T cell death: ADP-ribosylation of cell surface proteins by ART2 activates the cytolytic P2X7 purinoceptor

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362096

Toxicology. Protecting liver from painkiller's lethal dose

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362096

Targeted disruption of cd39/ATP diphosphohydrolase results in disordered hemostasis and thromboregulation.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3362096

TLR9 and the recognition of self and non-self nucleic acids

23 September 2018

1 reference

12 December 2020

Protection against acetaminophen toxicity in CYP1A2 and CYP2E1 double-null mice

1 reference

12 December 2020

Temporal variation in hepatotoxicity and metabolism of acetaminophen in mice

1 reference

12 December 2020

Expression of P2X receptors on immune cells in the rat liver during postnatal development

1 reference

12 December 2020

Cyclophilin A is a damage-associated molecular pattern molecule that mediates acetaminophen-induced liver injury

1 reference

12 December 2020

Pretreatment of mice with macrophage inactivators decreases acetaminophen hepatotoxicity and the formation of reactive oxygen and nitrogen species

1 reference

12 December 2020

Identifiers

DOI

10.1152/AJPGI.00352.2011

1 reference

11 August 2017

1 reference

11 August 2017

PubMed publication ID

22383490

1 reference