(Q35998797)

11 August 2017

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title

WNT signalling and haematopoiesis: a WNT-WNT situation (English)

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11 August 2017

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Frank J T Staal

1

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PubMed ID

15630426

11 August 2017

Hans C Clevers

series ordinal

2

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11 August 2017

1 January 2005

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Nature Reviews Immunology

11 August 2017

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11 August 2017

5

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11 August 2017

21-30

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11 August 2017

1

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Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome

11 August 2017

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TCF transcription factors, mediators of Wnt-signaling in development and cancer

31 March 2020

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Sonic hedgehog induces the proliferation of primitive human hematopoietic cells via BMP regulation

31 March 2020

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Bone morphogenetic proteins regulate the developmental program of human hematopoietic stem cells

31 March 2020

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31 March 2020

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Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway

31 March 2020

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31 March 2020

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Specificity of WNT-receptor interactions

31 March 2020

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Frizzleds: new members of the superfamily of G-protein-coupled receptors

31 March 2020

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WNT-frizzled signaling via cyclic GMP.

31 March 2020

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The WNT/calcium pathway: biochemical mediators, tools and future requirements

31 March 2020

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Wnt breakers in colon cancer

31 March 2020

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Wnt-frizzled signaling to G-protein-coupled effectors

31 March 2020

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Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta

31 March 2020

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The significance of the Wnt pathway in the pathology of human cancers

31 March 2020

1 reference

The ins and outs of Wingless signaling.

31 March 2020

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Convergence of Wnt, beta-catenin, and cadherin pathways

31 March 2020

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You Wnt some, you lose some: oncogenes in the Wnt signaling pathway

31 March 2020

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The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors

31 March 2020

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The chromatin remodelling factor Brg-1 interacts with beta-catenin to promote target gene activation

31 March 2020

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Chibby, a nuclear beta-catenin-associated antagonist of the Wnt/Wingless pathway

31 March 2020

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ICAT inhibits beta-catenin binding to Tcf/Lef-family transcription factors and the general coactivator p300 using independent structural modules

31 March 2020

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Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex

31 March 2020

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Pygopus residues required for its binding to Legless are critical for transcription and development

31 March 2020

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Pygopus and Legless target Armadillo/beta-catenin to the nucleus to enable its transcriptional co-activator function.

31 March 2020

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A complex of Armadillo, Legless, and Pygopus coactivates dTCF to activate wingless target genes.

31 March 2020

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Wnt-5A augments repopulating capacity and primitive hematopoietic development of human blood stem cells in vivo.

31 March 2020

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A role for Wnt signalling in self-renewal of haematopoietic stem cells

31 March 2020

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Wnt proteins are lipid-modified and can act as stem cell growth factors

31 March 2020

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An HMG-box-containing T-cell factor required for thymocyte differentiation.

31 March 2020

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Nuclear localization and formation of beta-catenin-lymphoid enhancer factor 1 complexes are not sufficient for activation of gene expression

31 March 2020

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LEF-1, a gene encoding a lymphoid-specific protein with an HMG domain, regulates T-cell receptor alpha enhancer function [corrected]

31 March 2020

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Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice

31 March 2020

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Redundant regulation of T cell differentiation and TCRalpha gene expression by the transcription factors LEF-1 and TCF-1

31 March 2020

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Wnt3a-/--like phenotype and limb deficiency in Lef1(-/-)Tcf1(-/-) mice

31 March 2020

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Extensive alternative splicing and dual promoter usage generate Tcf-1 protein isoforms with differential transcription control properties

31 March 2020

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The beta-catenin--TCF-1 pathway ensures CD4(+)CD8(+) thymocyte survival

31 March 2020

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Thymic epithelial cells provide WNT signals to developing thymocytes.

31 March 2020

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Impaired mammary gland and lymphoid development caused by inducible expression of Axin in transgenic mice

31 March 2020

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Frizzled 9 knock-out mice have abnormal B-cell development

31 March 2020

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Deletion of β-catenin impairs T cell development

31 March 2020

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Beta-catenin is dispensable for hematopoiesis and lymphopoiesis

31 March 2020

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Tcf-1-mediated transcription in T lymphocytes: differential role for glycogen synthase kinase-3 in fibroblasts and T cells

31 March 2020

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Somatic activation of beta-catenin bypasses pre-TCR signaling and TCR selection in thymocyte development.

31 March 2020

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beta-Catenin expression enhances generation of mature thymocytes.

31 March 2020

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Crosstalk in the mouse thymus

31 March 2020

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Wnt glycoproteins regulate the expression of FoxN1, the gene defective in nude mice.

31 March 2020

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A transcriptional response to Wnt protein in human embryonic carcinoma cells

31 March 2020

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The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

31 March 2020

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Wnt target genes identified by DNA microarrays in immature CD34+ thymocytes regulate proliferation and cell adhesion.

31 March 2020

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ALY, a context-dependent coactivator of LEF-1 and AML-1, is required for TCRalpha enhancer function

31 March 2020

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Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism

31 March 2020

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The B cell antigen receptor regulates the transcriptional activator beta-catenin via protein kinase C-mediated inhibition of glycogen synthase kinase-3.

31 March 2020

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Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells.

31 March 2020

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Activation of the Wnt signaling pathway in chronic lymphocytic leukemia

31 March 2020

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Oncogenic homeodomain transcription factor E2A-Pbx1 activates a novel WNT gene in pre-B acute lymphoblastoid leukemia

31 March 2020

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Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML

31 March 2020

1 reference

The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma

31 March 2020

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Illegitimate WNT signaling promotes proliferation of multiple myeloma cells

31 March 2020

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Wnt5a inhibits B cell proliferation and functions as a tumor suppressor in hematopoietic tissue

31 March 2020

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Notch1 functions as a tumor suppressor in mouse skin

31 March 2020

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LEF1-mediated regulation of Delta-like1 links Wnt and Notch signaling in somitogenesis

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRI1529

1 reference

11 August 2017

1 reference

PubMed ID

15630426