(Q36006947)

English

Lin-28 homologue A (LIN28A) promotes cell cycle progression via regulation of cyclin-dependent kinase 2 (CDK2), cyclin D1 (CCND1), and cell division cycle 25 homolog A (CDC25A) expression in cancer

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scholarly article

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Europe PubMed Central

PMC publication ID

11 August 2017

Lin-28 homologue A (LIN28A) promotes cell cycle progression via regulation of cyclin-dependent kinase 2 (CDK2), cyclin D1 (CCND1), and cell division cycle 25 homolog A (CDC25A) expression in cancer (English)

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Dionyssios Katsaros

11

object named as

Dionyssios Katsaros

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Europe PubMed Central

PMC publication ID

11 August 2017

author name string

Ning Li

1

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Xiaomin Zhong

2

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Xiaojuan Lin

3

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Jinyi Guo

4

1 reference

Europe PubMed Central

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11 August 2017

Lian Zou

5

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Janos L Tanyi

6

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Zhongjun Shao

7

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Shun Liang

8

1 reference

Europe PubMed Central

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11 August 2017

Li-Ping Wang

9

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Wei-Ting Hwang

10

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Kathleen Montone

12

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Xia Zhao

13

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Lin Zhang

14

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Europe PubMed Central

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11 August 2017

language of work or name

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publication date

30 March 2012

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Europe PubMed Central

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11 August 2017

number of pages

12

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based on heuristic

inferred from page(s)

Journal of Biological Chemistry

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Europe PubMed Central

PMC publication ID

11 August 2017

287

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Europe PubMed Central

PMC publication ID

11 August 2017

21

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Europe PubMed Central

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11 August 2017

17386-17397

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Europe PubMed Central

PMC publication ID

11 August 2017

High expression of Lin28 is associated with tumour aggressiveness and poor prognosis of patients in oesophagus cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

LIN28 expression and prognostic value in hepatocellular carcinoma patients who meet the Milan criteria and undergo hepatectomy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Lin28b reprograms adult bone marrow hematopoietic progenitors to mediate fetal-like lymphopoiesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Human ovarian cancer stem/progenitor cells are stimulated by doxorubicin but inhibited by Mullerian inhibiting substance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Glycine decarboxylase activity drives non-small cell lung cancer tumor-initiating cells and tumorigenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Molecular basis for interaction of let-7 microRNAs with Lin28

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Importance of the NCp7-like domain in the recognition of pre-let-7g by the pluripotency factor Lin28.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

MiR-181 mediates cell differentiation by interrupting the Lin28 and let-7 feedback circuit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

The Lin28/let-7 axis regulates glucose metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Germline genetic variants disturbing the Let-7/LIN28 double-negative feedback loop alter breast cancer susceptibility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Expression and interdependencies of pluripotency factors LIN28, OCT3/4, NANOG and SOX2 in human testicular germ cells and tumours of the testis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

LIN28B fosters colon cancer migration, invasion and transformation through let-7-dependent and -independent mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Lin-28 reactivation is required for let-7 repression and proliferation in human small cell lung cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

LIN28B promotes colon cancer progression and metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

LIN28B polymorphisms influence susceptibility to epithelial ovarian cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Evidence that Lin28 stimulates translation by recruiting RNA helicase A to polysomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Double-negative feedback loop between reprogramming factor LIN28 and microRNA let-7 regulates aldehyde dehydrogenase 1-positive cancer stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Identification of microRNAs regulating reprogramming factor LIN28 in embryonic stem cells and cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Lin-28B expression promotes transformation and invasion in human hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

LIN28 alters cell fate succession and acts independently of the let-7 microRNA during neurogliogenesis in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Pluripotency factors Lin28 and Oct4 identify a sub-population of stem cell-like cells in ovarian cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Lin28-mediated post-transcriptional regulation of Oct4 expression in human embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in mouse embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

A role for Lin28 in primordial germ-cell development and germ-cell malignancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

The pluripotency factor LIN28 marks undifferentiated spermatogonia in mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Lin28 promotes transformation and is associated with advanced human malignancies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Genetic variation in LIN28B is associated with the timing of puberty

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Genome-wide association study identifies sequence variants on 6q21 associated with age at menarche

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Genome-wide association studies identify loci associated with age at menarche and age at natural menopause

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Meta-analysis of genome-wide association data identifies two loci influencing age at menarche

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Lin28 modulates cell growth and associates with a subset of cell cycle regulator mRNAs in mouse embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

let-7 Overexpression leads to an increased fraction of cells in G2/M, direct down-regulation of Cdc34, and stabilization of Wee1 kinase in primary fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Genetic analysis of the role of the reprogramming gene LIN-28 in human embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Identification of ten loci associated with height highlights new biological pathways in human growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Selective blockade of microRNA processing by Lin28

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Dynamic gene expression of Lin-28 during embryonic development in mouse and chicken

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Induced pluripotent stem cell lines derived from human somatic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

The let-7 microRNA represses cell proliferation pathways in human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Localization of the developmental timing regulator Lin28 to mRNP complexes, P-bodies and stress granules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Lin-28 binds IGF-2 mRNA and participates in skeletal myogenesis by increasing translation efficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Identification and characterization of lin-28 homolog B (LIN28B) in human hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Extensive post-transcriptional regulation of microRNAs and its implications for cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

RAS is regulated by the let-7 microRNA family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Temporally regulated expression of Lin-28 in diverse tissues of the developing mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

Conservation of the heterochronic regulator Lin-28, its developmental expression and microRNA complementary sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

2 October 2017

A LIN28-dependent structural change in pre-let-7g directly inhibits dicer processing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

11 July 2018

Musashi1 cooperates in abnormal cell lineage protein 28 (Lin28)-mediated let-7 family microRNA biogenesis in early neural differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

11 July 2018

Histone H2a mRNA interacts with Lin28 and contains a Lin28-dependent posttranscriptional regulatory element

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

11 July 2018

Heterochronic mutants of the nematode Caenorhabditis elegans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

11 July 2018

Genome-wide studies reveal that Lin28 enhances the translation of genes important for growth and survival of human embryonic stem cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

23 September 2018

Pluripotent factor lin-28 and its homologue lin-28b in epithelial ovarian cancer and their associations with disease outcomes and expression of let-7a and IGF-II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366838

23 September 2018

Lin28: A microRNA regulator with a macro role

1 reference

https://pubmed.ncbi.nlm.nih.gov/22467868

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RNA-binding protein LIN28 is a marker for primary extragonadal germ cell tumors: an immunohistochemical study of 131 cases

1 reference

https://pubmed.ncbi.nlm.nih.gov/22467868

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RNA-binding protein LIN28 is a marker for testicular germ cell tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22467868

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RNA-binding protein LIN28 is a sensitive marker of ovarian primitive germ cell tumours

1 reference

https://pubmed.ncbi.nlm.nih.gov/22467868

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M111.321158

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

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