(Q36008885)

11 August 2017

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title

Ribavirin and lethal mutagenesis of poliovirus: molecular mechanisms, resistance and biological implications (English)

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11 August 2017

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Marco Vignuzzi

1

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Raul Andino

series ordinal

3

object named as

Raul Andino

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11 August 2017

Jeffrey K Stone

2

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PubMed ID

15649563

11 August 2017

language of work or name

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1 February 2005

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11 August 2017

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11 August 2017

107

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11 August 2017

173-181

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11 August 2017

2

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Curing of foot-and-mouth disease virus from persistently infected cells by ribavirin involves enhanced mutagenesis.

11 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Molecular approaches for the treatment of hemorrhagic fever virus infections.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Poliovirus RNA-dependent RNA polymerase (3D(pol)). Assembly of stable, elongation-competent complexes by using a symmetrical primer-template substrate (sym/sub)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Ribavirin inhibits proliferation of bovine respiratory syncytial virus in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

The broad spectrum antiviral nucleoside ribavirin as a substrate for a viral RNA capping enzyme.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

The mechanism of action of ribavirin: lethal mutagenesis of RNA virus genomes mediated by the viral RNA-dependent RNA polymerase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Inhibition of hepatitis delta virus RNA replication in primary woodchuck hepatocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Viral RNA mutations are region specific and increased by ribavirin in a full-length hepatitis C virus replication system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Inhibition of sandfly fever Sicilian virus (Phlebovirus) replication in vitro by antiviral compounds

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Interferon, ribavirin, 6-azauridine and glycyrrhizin: antiviral compounds active against pathogenic flaviviruses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Ribavirin's antiviral mechanism of action: lethal mutagenesis?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

RNA virus error catastrophe: direct molecular test by using ribavirin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Rapid evolution of viral RNA genomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Viruses at the edge of adaptation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Quasispecies Structure and Persistence of RNA Viruses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Basic concepts in RNA virus evolution

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

RNA virus mutations and fitness for survival

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

A constant rate of spontaneous mutation in DNA-based microbes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Rates of spontaneous mutation among RNA viruses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

The distribution of rates of spontaneous mutation over viruses, prokaryotes, and eukaryotes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Selforganization of matter and the evolution of biological macromolecules

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

On the nature of virus quasispecies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Error catastrophe and antiviral strategy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Statistical geometry in sequence space: a method of quantitative comparative sequence analysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Ribavirin enhancement of hepatitis C virus core antigen-specific type 1 T helper cell response correlates with the increased IL-12 level

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Visna virus as an in vitro model for human immunodeficiency virus and inhibition by ribavirin, phosphonoformate, and 2',3'-dideoxynucleosides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Quantitative real-time PCR detection of Rift Valley fever virus and its application to evaluation of antiviral compounds

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Poliovirus RNA-dependent RNA polymerase (3Dpol): structural, biochemical, and biological analysis of conserved structural motifs A and B

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Modulation of hepatitis C virus quasispecies heterogeneity by interferon-alpha and ribavirin therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Structure of the RNA-dependent RNA polymerase of poliovirus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Rapid evolution of RNA genomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Prospects for treatment of viral hemorrhagic fevers with ribavirin, a broad-spectrum antiviral drug

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

The antiviral compound ribavirin modulates the T helper (Th) 1/Th2 subset balance in hepatitis B and C virus-specific immune responses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Ribavirin inhibits West Nile virus replication and cytopathic effect in neural cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Ribavirin Induces Error-Prone Replication of GB Virus B in Primary Tamarin Hepatocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Mechanism of action of ribavirin in the combination treatment of chronic HCV infection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Effect of ribavirin on virus load and quasispecies distribution in patients infected with hepatitis C virus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Lethal mutagenesis of HIV with mutagenic nucleoside analogs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Hepatitis C virus RNA-dependent RNA polymerase (NS5B) as a mediator of the antiviral activity of ribavirin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Retrovirus mutation rates and their role in genetic variation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Ribavirin suppresses replication of lymphadenopathy-associated virus in cultures of human adult T lymphocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Lassa fever. Effective therapy with ribavirin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Characterization of in vitro and in vivo antiviral activity of lactoferrin and ribavirin upon hantavirus.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

A single mutation in poliovirus RNA-dependent RNA polymerase confers resistance to mutagenic nucleotide analogs via increased fidelity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Pharmacokinetics and absolute bioavailability of ribavirin in healthy volunteers as determined by stable-isotope methodology.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

The importance of IMP dehydrogenase inhibition in the broad spectrum antiviral activity of ribavirin and selenazofurin.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Lethal mutagenesis of the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Ribavirin causes error catastrophe during Hantaan virus replication.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Response of foot-and-mouth disease virus to increased mutagenesis: influence of viral load and fitness in loss of infectivity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Antiviral activity and mode of action studies of ribavirin and mycophenolic acid against orthopoxviruses in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Selective inhibition of arthropod-borne and arenaviruses in vitro by 3'-fluoro-3'-deoxyadenosine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Lack of evidence for proofreading mechanisms associated with an RNA virus polymerase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Experimental Lassa fever virus infection successfully treated with ribavirin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

The cooperative effect of interferon-alpha and ribavirin on subacute sclerosing panencephalitis (SSPE) virus infections, in vitro and in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Mechanisms of action of ribavirin in antiviral therapies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Ribavirin polarizes human T cell responses towards a Type 1 cytokine profile.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Retrovirus variation and reverse transcription: abnormal strand transfers result in retrovirus genetic variation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Inhibition of Semliki Forest virus multiplication by ribavirin: a potential method for the monitoring of antiviral agents in serum

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Mutagenic and inhibitory effects of ribavirin on hepatitis C virus RNA polymerase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Effect of ribavirin triphosphate on primer generation and elongation during influenza virus transcription in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Mode of action of ribavirin: effect of nucleotide pool alterations on influenza virus ribonucleoprotein synthesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Effects of selenazofurin and ribavirin and their 5'-triphosphates on replicative functions of influenza A and B viruses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Respiratory syncytial virus (RSV) disease and prospects for its control

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Comparison of the inhibition of human metapneumovirus and respiratory syncytial virus by ribavirin and immune serum globulin in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Use of cotton rats to evaluate the efficacy of antivirals in treatment of measles virus infections

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Ribavirin treatment up-regulates antiviral gene expression via the interferon-stimulated response element in respiratory syncytial virus-infected epithelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

The effect of ribavirin and IMPDH inhibitors on hepatitis C virus subgenomic replicon RNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

Mutation Frequencies at Defined Single Codon Sites in Vesicular Stomatitis Virus and Poliovirus Can Be Increased Only Slightly by Chemical Mutagenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

7 January 2021

Pol gene quasispecies of human immunodeficiency virus: mutations associated with drug resistance in virus from patients undergoing no drug therapy

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

7 January 2021

Molecular mechanisms of action of ribavirin

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

7 January 2021

Synergistic anti-influenza virus A (H1N1) activities of PM-523 (polyoxometalate) and ribavirin in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

7 January 2021

Inhibition of Crimean-Congo hemorrhagic fever viral infectivity yields in vitro by ribavirin

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2004.11.007

7 January 2021

10.1016/J.VIRUSRES.2004.11.007

Identifiers

DOI

1 reference

11 August 2017

1 reference

PubMed ID

15649563