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CCN3 modulates bone turnover and is a novel regulator of skeletal metastasis
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Europe PubMed Central
PMC publication ID
3368020
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22427255%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
title
CCN3 modulates bone turnover and is a novel regulator of skeletal metastasis
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3368020
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22427255%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
author
Véronique Ouellet
series ordinal
1
1 reference
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Europe PubMed Central
PMC publication ID
3368020
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22427255%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
author name string
Peter M Siegel
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3368020
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22427255%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
publication date
18 March 2012
1 reference
stated in
Europe PubMed Central
PMC publication ID
3368020
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22427255%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
published in
Journal of Cell Communication and Signaling
1 reference
stated in
Europe PubMed Central
PMC publication ID
3368020
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22427255%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
volume
6
1 reference
stated in
Europe PubMed Central
PMC publication ID
3368020
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22427255%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
issue
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3368020
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22427255%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
page(s)
73-85
1 reference
stated in
Europe PubMed Central
PMC publication ID
3368020
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22427255%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
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CCN3/NOV inhibits BMP-2-induced osteoblast differentiation by interacting with BMP and Notch signaling pathways
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2 October 2017
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2 October 2017
A novel mechanism for BCR-ABL action: stimulated secretion of CCN3 is involved in growth and differentiation regulation
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Nuclear addressing provides a clue for the transforming activity of amino-truncated CCN3 proteins
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2 October 2017
In Ewing's sarcoma CCN3(NOV) inhibits proliferation while promoting migration and invasion of the same cell type
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CCN3 (NOV) interacts with connexin43 in C6 glioma cells: possible mechanism of connexin-mediated growth suppression
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Estrogen regulation in human breast cancer cells of new downstream gene targets involved in estrogen metabolism, cell proliferation and cell transformation
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2 October 2017
The oestrogen receptors (ER alpha and ER beta) and their role in breast cancer: a review
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2 October 2017
The CCN family: a new stimulus package
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2 October 2017
Adhesion of endothelial cells to NOV is mediated by the integrins alphavbeta3 and alpha5beta1
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2 October 2017
A multigenic program mediating breast cancer metastasis to bone
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2 October 2017
Osteoclast differentiation and activation
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2 October 2017
Human WISP1v, a member of the CCN family, is associated with invasive cholangiocarcinoma
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2 October 2017
Proposal for a unified CCN nomenclature
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retrieved
2 October 2017
Expression of connective tissue growth factor/hypertrophic chondrocyte-specific gene product 24 (CTGF/Hcs24) during fracture healing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
2 October 2017
Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
2 October 2017
Matrix metalloproteinases cleave connective tissue growth factor and reactivate angiogenic activity of vascular endothelial growth factor 165
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
2 October 2017
The nephroblastoma overexpressed gene (NOV/ccn3) protein associates with Notch1 extracellular domain and inhibits myoblast differentiation via Notch signaling pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
2 October 2017
Chordin-like CR domains and the regulation of evolutionarily conserved extracellular signaling systems.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
2 October 2017
The expression of ccn3(nov) gene in musculoskeletal tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
2 October 2017
Elevated levels of connective tissue growth factor, WISP-1, and CYR61 in primary breast cancers associated with more advanced features.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
2 October 2017
Connective tissue growth factor binds vascular endothelial growth factor (VEGF) and inhibits VEGF-induced angiogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
2 October 2017
Minireview: the OPG/RANKL/RANK system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
2 October 2017
A novel variant of WISP1 lacking a Von Willebrand type C module overexpressed in scirrhous gastric carcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
2 October 2017
Differential expression of the ccn3 (nov) proto-oncogene in human prostate cell lines and tissues.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
2 October 2017
The expression of ccn3 (nov) RNA and protein in the rat central nervous system is developmentally regulated
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
2 October 2017
NOV (nephroblastoma overexpressed) and the CCN family of genes: structural and functional issues
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
2 October 2017
The expression of osteoprotegerin and RANK ligand and the support of osteoclast formation by stromal-osteoblast lineage cells is developmentally regulated
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
2 October 2017
Effects of transforming growth factor-beta signaling on chondrogenesis in mouse chondrogenic EC cells, ATDC5.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
2 October 2017
Nuclear localisation of NOVH protein: a potential role for NOV in the regulation of gene expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
2 October 2017
Plasminogen activator inhibitor type-2 (PAI-2) gene transcription requires a novel NF-kappaB-like transcriptional regulatory motif
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
2 October 2017
The connective tissue growth factor/cysteine-rich 61/nephroblastoma overexpressed (CCN) family
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
2 October 2017
Binding properties and distribution of insulin-like growth factor binding protein-related protein 3 (IGFBP-rP3/NovH), an additional member of the IGFBP Superfamily
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
2 October 2017
The C-terminal domain of the regulatory protein NOVH is sufficient to promote interaction with fibulin 1C: a clue for a role of NOVH in cell-adhesion signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
2 October 2017
WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
2 October 2017
Identification of rCop-1, a new member of the CCN protein family, as a negative regulator for cell transformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
2 October 2017
novH: differential expression in developing kidney and Wilm's tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
2 October 2017
Chromosomal mapping and expression of the human cyr61 gene in tumour cells from the nervous system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
2 October 2017
Identification of a family of low-affinity insulin-like growth factor binding proteins (IGFBPs): characterization of connective tissue growth factor as a member of the IGFBP superfamily
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
2 October 2017
Cyr61 and Fisp12 are both ECM-associated signaling molecules: activities, metabolism, and localization during development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
2 October 2017
Assembly and routing of von Willebrand factor variants: the requirements for disulfide-linked dimerization reside within the carboxy-terminal 151 amino acids
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
2 October 2017
Proviral Rearrangements and Overexpression of a New Cellular Gene (nov) in Myeloblastosis-Associated Virus Type 1-Induced Nephroblastomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
2 October 2017
Alternative splicing of CCN mRNAs .... it has been upon us.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
11 July 2018
Domain-specific CCN3 antibodies as unique tools for structural and functional studies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
11 July 2018
Alternative splicing of type II procollagen pre-mRNA in chondrocytes is oppositely regulated by BMP-2 and TGF-beta1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
11 July 2018
The heparin-binding 10 kDa fragment of connective tissue growth factor (CTGF) containing module 4 alone stimulates cell adhesion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
11 July 2018
Binding properties of insulin-like growth factor binding protein-3 (IGFBP-3), IGFBP-3 N- and C-terminal fragments, and structurally related proteins mac25 and connective tissue growth factor measured using a biosensor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
11 July 2018
Purification and characterization of novel heparin-binding growth factors in uterine secretory fluids. Identification as heparin-regulated Mr 10,000 forms of connective tissue growth factor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
11 July 2018
Regulatory role of CCN3 in melanoma cell interaction with the extracellular matrix
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
23 September 2018
The aminoterminal insulin-like growth factor (IGF) binding domain of IGF binding protein-3 cannot be functionally substituted by the structurally homologous domain of CCN3.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
23 September 2018
Expression and regulation of CCN genes in murine osteoblasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
23 September 2018
NOV (CCN3) regulation in the growth plate and CCN family member expression in cartilage neoplasia.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
23 September 2018
Low density lipoprotein receptor-related protein (LRP) is a heparin-dependent adhesion receptor for connective tissue growth factor (CTGF) in rat activated hepatic stellate cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
23 September 2018
Amino- and carboxyl-terminal fragments of insulin-like growth factor (IGF) binding protein-3 cooperate to bind IGFs with high affinity and inhibit IGF receptor interactions.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
23 September 2018
Organization and expression of the Cyr61 gene in normal human fibroblasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
23 September 2018
MVLN cells: a bioluminescent MCE-7-derived cell line to study the modulation of estrogenic activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
23 September 2018
Evaluation of metastatic potential in prostate carcinoma: an in vivo model
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3368020
retrieved
23 September 2018
Nov gene encodes adhesion factor for vascular smooth muscle cells and is dynamically regulated in response to vascular injury
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22427255
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Matrix Metalloproteinase-9 Silencing by RNA Interference Triggers the Migratory-adhesive Switch in Ewing's Sarcoma Cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22427255
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Immunocytochemical localization of NOVH protein and ultrastructural characteristics of NCI-H295R cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22427255
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Transcriptional profiling of bone regeneration. Insight into the molecular complexity of wound repair
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22427255
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1007/S12079-012-0161-7
1 reference
stated in
Europe PubMed Central
PMC publication ID
3368020
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22427255%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
PMC publication ID
3368020
1 reference
stated in
Europe PubMed Central
PMC publication ID
3368020
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22427255%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
PubMed publication ID
22427255
1 reference
stated in
Europe PubMed Central
PMC publication ID
3368020
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22427255%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
ResearchGate publication ID
221715676
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