(Q36018407)

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Combination immunotherapy after ASCT for multiple myeloma using MAGE-A3/Poly-ICLC immunizations followed by adoptive transfer of vaccine-primed and costimulated autologous T cells

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Europe PubMed Central

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11 August 2017

Combination immunotherapy after ASCT for multiple myeloma using MAGE-A3/Poly-ICLC immunizations followed by adoptive transfer of vaccine-primed and costimulated autologous T cells (English)

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Europe PubMed Central

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11 August 2017

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multiple myeloma

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based on heuristic

25

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Carl H June

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11 August 2017

Bruce L. Levine

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Bruce L Levine

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Edward A. Stadtmauer

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Edward A Stadtmauer

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Dan T Vogl

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Nicole A Aqui

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Hong-Bin Fang

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Todd Milliron

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Saul Yanovich

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Gorgun Akpek

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Kathleen Ruehle

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Kathleen Ruehle

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Sunita Philip

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Ashraf Z Badros

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Ashraf Badros

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Brendan M Weiss

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Brendan M Weiss

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Naseem D S Kerr

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Naseem Kerr

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Michael Kalos

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Aaron P Rapoport

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Yin Yan Xu

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Ling Cai

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Patricia Tsao

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Alan Cross

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Dean Mann

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Andrea Brennan

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Zhaohui Zheng

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Scott E Strome

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Andres M Salazar

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publication date

11 February 2014

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Clinical Cancer Research

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1355-1365

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describes a project that uses

1 reference

Europe PubMed Central

18 June 2022

https://europepmc.org/article/PMC/4557204

based on heuristic

inferred from PubMed Central ID database lookup

Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557204

2 October 2017

Vaccination with dendritic cell/tumor fusions following autologous stem cell transplant induces immunologic and clinical responses in multiple myeloma patients

1 reference

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2 October 2017

Chimeric antigen receptor-modified T cells for acute lymphoid leukemia

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2 October 2017

Persistent antigen at vaccination sites induces tumor-specific CD8⁺ T cell sequestration, dysfunction and deletion

1 reference

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2 October 2017

Lenalidomide after stem-cell transplantation for multiple myeloma

1 reference

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2 October 2017

Induction of MAGE-A3 and HPV-16 immunity by Trojan vaccines in patients with head and neck carcinoma

1 reference

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2 October 2017

Lenalidomide-induced immunomodulation in multiple myeloma: impact on vaccines and antitumor responses

1 reference

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2 October 2017

Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia

1 reference

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2 October 2017

Combination immunotherapy using adoptive T-cell transfer and tumor antigen vaccination on the basis of hTERT and survivin after ASCT for myeloma.

1 reference

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2 October 2017

Transfer of influenza vaccine-primed costimulated autologous T cells after stem cell transplantation for multiple myeloma leads to reconstitution of influenza immunity: results of a randomized clinical trial.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557204

2 October 2017

Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant

1 reference

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2 October 2017

Rapid immune recovery and graft-versus-host disease-like engraftment syndrome following adoptive transfer of Costimulated autologous T cells.

1 reference

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2 October 2017

Synthetic double-stranded RNAs are adjuvants for the induction of T helper 1 and humoral immune responses to human papillomavirus in rhesus macaques

1 reference

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2 October 2017

The anti-cancer agents lenalidomide and pomalidomide inhibit the proliferation and function of T regulatory cells.

1 reference

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2 October 2017

A North American brain tumor consortium phase II study of poly-ICLC for adult patients with recurrent anaplastic gliomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557204

2 October 2017

A phase II clinical trial of poly-ICLC with radiation for adult patients with newly diagnosed supratentorial glioblastoma: a North American Brain Tumor Consortium (NABTC01-05).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557204

2 October 2017

Differential pattern of CD4+ and CD8+ T-cell immunity to MAGE-A1/A2/A3 in patients with monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma

1 reference

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Chronic lymphocytic leukemia T cells show impaired immunological synapse formation that can be reversed with an immunomodulating drug

1 reference

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Cancer testis antigens in human melanoma stem cells: expression, distribution, and methylation status

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Toll like receptor-3 ligand poly-ICLC promotes the efficacy of peripheral vaccinations with tumor antigen-derived peptide epitopes in murine CNS tumor models

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Timely reconstitution of immune competence affects clinical outcome following autologous stem cell transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557204

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Multiepitope Trojan antigen peptide vaccines for the induction of antitumor CTL and Th immune responses

1 reference

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Tumor regression and autoimmunity after reversal of a functionally tolerant state of self-reactive CD8+ T cells.

1 reference

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2 October 2017

T cells from the tumor microenvironment of patients with progressive myeloma can generate strong, tumor-specific cytolytic responses to autologous, tumor-loaded dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557204

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Superiority of tandem autologous transplantation over standard therapy for previously untreated multiple myeloma.

1 reference

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1 reference

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Autoantibodies against cancer antigens

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Longitudinal analysis and prognostic effect of cancer-testis antigen expression in multiple myeloma.

1 reference

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Long-term outcome results of the first tandem autotransplant trial for multiple myeloma.

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Restoration of immunity in lymphopenic individuals with cancer by vaccination and adoptive T-cell transfer.

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GMP production and testing of Xcellerated T Cells for the treatment of patients with CLL.

1 reference

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23 September 2018

Enhancement of cytokine production and AP-1 transcriptional activity in T cells by thalidomide-related immunomodulatory drugs

1 reference

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Thalidomide and immunomodulatory derivatives augment natural killer cell cytotoxicity in multiple myeloma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557204

23 September 2018

Thalidomide and its analogs overcome drug resistance of human multiple myeloma cells to conventional therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557204

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Life-threatening infections occurring more than 3 months after BMT. 18 UK Bone Marrow Transplant Teams.

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Graft-versus-myeloma effect: proof of principle

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1 reference

https://pubmed.ncbi.nlm.nih.gov/24520093

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/24520093

12 December 2020

based on heuristic

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p27kip1 functions as an anergy factor inhibiting interleukin 2 transcription and clonal expansion of alloreactive human and mouse helper T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/24520093

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inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/24520093

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inferred from PubMed ID database lookup

Early lymphocyte recovery predicts superior survival after autologous hematopoietic stem cell transplantation in multiple myeloma or non-Hodgkin lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/24520093

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based on heuristic

inferred from PubMed ID database lookup

Activated marrow-infiltrating lymphocytes effectively target plasma cells and their clonogenic precursors

1 reference

https://pubmed.ncbi.nlm.nih.gov/24520093

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cancer-testis antigens CT7 (MAGE-C1) and MAGE-A3/6 are commonly expressed in multiple myeloma and correlate with plasma-cell proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/24520093

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based on heuristic

inferred from PubMed ID database lookup

Immunoselection of functional CMRF-56+ blood dendritic cells from multiple myeloma patients for immunotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/24520093

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based on heuristic

inferred from PubMed ID database lookup

Cancer/testis genes in multiple myeloma: expression patterns and prognosis value determined by microarray analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24520093

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inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/24520093

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1 reference

https://pubmed.ncbi.nlm.nih.gov/24520093

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/1078-0432.CCR-13-2817

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

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