(Q36018639)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26081744%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

title

Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26081744%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

0 references

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26081744%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Matthew C Hill

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26081744%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Ryan W Himes

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26081744%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

James Wilson

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26081744%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

William R. Lagor

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26081744%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

author name string

Beatrice Bissig-Choisat

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26081744%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Xavier Legras

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26081744%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Pradip K Saha

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26081744%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Leon Chen

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26081744%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Peter Bell

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26081744%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Francis P Pankowicz

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26081744%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Mercedes Barzi

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26081744%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Claudia Kettlun Leyton

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26081744%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Hon-Chiu Eastwood Leung

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26081744%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Robert L Kruse

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26081744%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

John A Goss

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26081744%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Lawrence Chan

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26081744%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Karl-Dimiter Bissig

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26081744%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

language of work or name

English

0 references

publication date

17 June 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26081744%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

published in

Nature Communications

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26081744%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

volume

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26081744%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

page(s)

7339

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26081744%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

17 February 2020

copyright license

start time

17 June 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4557302/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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JCL Roundtable: diagnosis of severe familial hypercholesterolemia

2 October 2017

1 reference

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Lipoprotein(a) concentrations, rosuvastatin therapy, and residual vascular risk: an analysis from the JUPITER Trial (Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin).

2 October 2017

1 reference

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New potential cell source for hepatocyte transplantation: discarded livers from metabolic disease liver transplants.

2 October 2017

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Lipoprotein(a): resurrected by genetics

2 October 2017

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Adeno-associated virus serotype 8 gene therapy leads to significant lowering of plasma cholesterol levels in humanized mouse models of homozygous and heterozygous familial hypercholesterolemia

2 October 2017

1 reference

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Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells

2 October 2017

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Evaluation of adeno-associated viral vectors for liver-directed gene transfer in dogs.

2 October 2017

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Gene therapy in a humanized mouse model of familial hypercholesterolemia leads to marked regression of atherosclerosis

2 October 2017

1 reference

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Induced pluripotent stem cell-derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice

2 October 2017

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Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells.

2 October 2017

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Biological, clinical and population relevance of 95 loci for blood lipids

2 October 2017

1 reference

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Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment

2 October 2017

1 reference

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The pleiotropic effects of natural AAV infections on liver-directed gene transfer in macaques

2 October 2017

1 reference

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Systematic evaluation of AAV vectors for liver directed gene transfer in murine models.

2 October 2017

1 reference

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Analysis of AAV serotypes 1-9 mediated gene expression and tropism in mice after systemic injection

2 October 2017

1 reference

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Repopulation of adult and neonatal mice with human hepatocytes: a chimeric animal model

2 October 2017

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Robust expansion of human hepatocytes in Fah-/-/Rag2-/-/Il2rg-/- mice

2 October 2017

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Liver transduction with recombinant adeno-associated virus is primarily restricted by capsid serotype not vector genotype

2 October 2017

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Gene therapy: twenty-first century medicine

2 October 2017

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Near completely humanized liver in mice shows human-type metabolic responses to drugs

2 October 2017

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Homozygous familial hypercholesterolemia and its management

2 October 2017

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Clades of Adeno-associated viruses are widely disseminated in human tissues.

2 October 2017

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Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy

2 October 2017

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Hepatitis C virus replication in mice with chimeric human livers

2 October 2017

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Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery

2 October 2017

1 reference

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Serial inbreeding of rabbits with hereditary hyperlipidemia (WHHL-rabbit).

2 October 2017

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Lipoprotein receptors in the liver. Control signals for plasma cholesterol traffic

2 October 2017

1 reference

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High-yield preparation of isolated rat liver parenchymal cells: a biochemical and fine structural study

2 October 2017

1 reference

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The LDL receptor locus in familial hypercholesterolemia: mutational analysis of a membrane protein

2 October 2017

1 reference

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Mouse hepatocytes migrate to liver parenchyma and function indefinitely after intrasplenic transplantation

2 October 2017

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Molecular genetics of the LDL receptor gene in familial hypercholesterolemia

2 October 2017

1 reference

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Chapter 4 Preparation of Isolated Rat Liver Cells

2 October 2017

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2 October 2017

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Naturally occurring singleton residues in AAV capsid impact vector performance and illustrate structural constraints.

11 July 2018

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Binding and degradation of low density lipoproteins by cultured human fibroblasts. Comparison of cells from a normal subject and from a patient with homozygous familial hypercholesterolemia.

11 July 2018

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Treatment of hereditary tyrosinaemia type I by inhibition of 4-hydroxyphenylpyruvate dioxygenase

11 July 2018

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Natural killer T cells in lipoprotein metabolism and atherosclerosis.

11 July 2018

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Familial hypercholesterolemias: prevalence, genetics, diagnosis and screening recommendations from the National Lipid Association Expert Panel on Familial Hypercholesterolemia

23 September 2018

1 reference

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Vascular calcifications in homozygote familial hypercholesterolemia

23 September 2018

1 reference

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Analysis of tumors arising in male B6C3F1 mice with and without AAV vector delivery to liver.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557302

Expression of human cytochromes P450 in chimeric mice with humanized liver.

23 September 2018

1 reference

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LDL immune complexes stimulate LDL receptor expression in U937 histiocytes via extracellular signal-regulated kinase and AP-1

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557302

Repopulation of mouse liver with human hepatocytes and in vivo infection with hepatitis B virus

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557302

Phospholipid and cholesteryl ester transfer activities in plasma from 14 vertebrate species. Relation to atherogenesis susceptibility.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557302

Genetically determined hypercholesterolemia in a rhesus monkey family due to a deficiency of the LDL receptor.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4557302

Genomic evidence for the absence of a functional cholesteryl ester transfer protein gene in mice and rats

23 September 2018

1 reference

12 December 2020

Characterization of an unusual lipoprotein similar to human lipoprotein a isolated from the baboon, Papio sp

1 reference

12 December 2020

Lipoprotein(a) in nonhuman primates. Presence and characteristics of Lp(a) immunoreactive materials using anti-human Lp(a) serum

1 reference

12 December 2020

Thyroid hormone rapidly induces hepatic LDL receptor mRNA levels in hypophysectomized rats

1 reference

12 December 2020

Liver-specific inactivation of the abetalipoproteinemia gene completely abrogates very low density lipoprotein/low density lipoprotein production in a viable conditional knockout mouse

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCOMMS8339

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26081744%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26081744%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

PubMed publication ID

26081744

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26081744%20AND%20SRC:MED&resulttype=core&format=json