(Q28748804)

1

0 references

Hui Li

2

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Luk H Vandenberghe

3

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Christian Hinderer

4

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Peter Bell

5

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Dawn Marchadier

6

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Aisha Wilson

7

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Debra Cromley

8

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Valeska Redon

9

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Hongwei Yu

10

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Daniel J Rader

Creative Commons Attribution 4.0 International

12

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language of work or name

English

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publication date

19 October 2010

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published in

PLOS One

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volume

5

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issue

10

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page(s)

e13424

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copyright license

start time

19 October 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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1 reference

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Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy

16 March 2017

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A pilot study of ex vivo gene therapy for homozygous familial hypercholesterolaemia

16 March 2017

1 reference

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Liver transplantation to provide low-density-lipoprotein receptors and lower plasma cholesterol in a child with homozygous familial hypercholesterolemia

16 March 2017

1 reference

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Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

16 March 2017

1 reference

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The role of liver sinusoidal cells in hepatocyte-directed gene transfer

7 April 2017

1 reference

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Homozygous familial hypercholesterolemia: long term clinical course and plasma exchange therapy for two individual patients and review of the literature

3 June 2018

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The pleiotropic effects of natural AAV infections on liver-directed gene transfer in macaques

3 June 2018

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Systematic evaluation of AAV vectors for liver directed gene transfer in murine models.

3 June 2018

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Long-term physiologically regulated expression of the low-density lipoprotein receptor in vivo using genomic DNA mini-gene constructs

3 June 2018

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Hepatic regulatory T cells and Kupffer cells are crucial mediators of systemic T cell tolerance to antigens targeting murine liver.

3 June 2018

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26 years of LDL--apheresis: a review of experience

3 June 2018

1 reference

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Adeno-associated virus-mediated gene transfer to nonhuman primate liver can elicit destructive transgene-specific T cell responses.

3 June 2018

1 reference

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AAV-mediated gene transfer for the treatment of hemophilia B: problems and prospects

3 June 2018

1 reference

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Manufacturing and characterizing AAV-based vectors for use in clinical studies

3 June 2018

1 reference

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Mechanisms of disease: genetic causes of familial hypercholesterolemia

3 June 2018

1 reference

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Gene therapy in disorders of lipoprotein metabolism

3 June 2018

1 reference

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Small animal models of cardiovascular disease: tools for the study of the roles of metabolic syndrome, dyslipidemia, and atherosclerosis

3 June 2018

1 reference

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Adeno-associated virus serotypes: vector toolkit for human gene therapy

3 June 2018

1 reference

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Gene therapy with novel adeno-associated virus vectors substantially diminishes atherosclerosis in a murine model of familial hypercholesterolemia

3 June 2018

1 reference

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Clades of Adeno-associated viruses are widely disseminated in human tissues.

3 June 2018

1 reference

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Non-physiological overexpression of the low density lipoprotein receptor (LDLr) gene in the liver induces pathological intracellular lipid and cholesterol storage

3 June 2018

1 reference

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3 June 2018

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Advances in experimental dyslipidemia and atherosclerosis

3 June 2018

1 reference

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Reduction of isoprostanes and regression of advanced atherosclerosis by apolipoprotein E.

3 June 2018

1 reference

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A mouse model of human familial hypercholesterolemia: markedly elevated low density lipoprotein cholesterol levels and severe atherosclerosis on a low-fat chow diet.

3 June 2018

1 reference

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Low density lipoprotein receptor-negative mice expressing human apolipoprotein B-100 develop complex atherosclerotic lesions on a chow diet: no accentuation by apolipoprotein(a).

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957433

Successful ex vivo gene therapy directed to liver in a patient with familial hypercholesterolaemia

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957433

Genetically determined hypercholesterolemia in a rhesus monkey family due to a deficiency of the LDL receptor.

3 June 2018

1 reference

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Receptor-mediated endocytosis: concepts emerging from the LDL receptor system

3 June 2018

1 reference

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Failure of complete bile diversion and oral bile acid therapy in the treatment of homozygous familial hypercholesterolemia

3 June 2018

1 reference

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Familial Hypercholesterolaemia Regression Study: a randomised trial of low-density-lipoprotein apheresis.

3 June 2018

1 reference

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Effective treatment of familial hypercholesterolaemia in the mouse model using adenovirus-mediated transfer of the VLDL receptor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013424

Low-density lipoprotein receptor gene therapy using helper-dependent adenovirus produces long-term protection against atherosclerosis in a mouse model of familial hypercholesterolemia

21 January 2018

1 reference

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The host response to adenovirus, helper-dependent adenovirus, and adeno-associated virus in mouse liver

21 January 2018

1 reference

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Prolonged correction of hyperlipidemia in mice with familial hypercholesterolemia using an adeno-associated viral vector expressing very-low-density lipoprotein receptor.

21 January 2018

1 reference

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Complete prevention of atherosclerosis in apoE-deficient mice by hepatic human apoE gene transfer with adeno-associated virus serotypes 7 and 8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013424

Sustained correction of disease in naive and AAV2-pretreated hemophilia B dogs: AAV2/8-mediated, liver-directed gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013424

Hepatic expression of apolipoprotein E inhibits progression of atherosclerosis without reducing cholesterol levels in LDL receptor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013424

Worldwide epidemiology of neutralizing antibodies to adeno-associated viruses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013424

Total correction of hemophilia A mice with canine FVIII using an AAV 8 serotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013424

Heparin binding directs activation of T cells against adeno-associated virus serotype 2 capsid

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013424

Adeno-associated virus capsid structure drives CD4-dependent CD8+ T cell response to vector encoded proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0013424

Regulatory requirements for clinical trial and marketing authorisation application for gene therapy medicinal products

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957433

Hepatic steatosis, insulin resistance, and adipose tissue disorders.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957433

In vivo correction of low density lipoprotein receptor deficiency in the Watanabe heritable hyperlipidemic rabbit with recombinant adenoviruses.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2957433

Regression of atherosclerosis induced by liver-directed gene transfer of apolipoprotein A-I in mice

27 November 2018

1 reference

12 December 2020

Thyroid hormone rapidly induces hepatic LDL receptor mRNA levels in hypophysectomized rats

1 reference

12 December 2020

Mouse models of atherosclerosis

1 reference

12 December 2020

Orthotopic liver transplantation for hepatic-based metabolic disorders

1 reference

12 December 2020