(Q36021571)

11 August 2017

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title

Molecular pathogenesis of childhood brain tumors (English)

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11 August 2017

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3

James T Rutka

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11 August 2017

Torsten Pietsch

1

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PubMed ID

15674478

11 August 2017

Michael D Taylor

series ordinal

2

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11 August 2017

1 November 2004

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Journal of Neuro-Oncology

11 August 2017

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11 August 2017

70

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11 August 2017

2

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11 August 2017

203-215

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https://scigraph.springernature.com/pub.10.1007/s11060-004-2750-7

11 August 2017

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cites work

Deletion mapping on chromosome 17p in medulloblastoma

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11060-004-2750-7

Nonrandom chromosomal gains in pilocytic astrocytomas of childhood.

21 January 2018

1 reference

12 December 2020

[Ganglioglioma of optic nerve in neurofibromatosis type 1. Case report and review of the literature]

1 reference

12 December 2020

Identification of extensive genomic loss and gain by comparative genomic hybridisation in malignant astrocytoma in children and young adults.

1 reference

12 December 2020

Disruption of Ini1 leads to peri-implantation lethality and tumorigenesis in mice

1 reference

12 December 2020

Altered neural cell fates and medulloblastoma in mouse patched mutants

1 reference

12 December 2020

Multiple genomic alterations including N-myc amplification in a primary large cell medulloblastoma.

1 reference

12 December 2020

Pilocytic astrocytomas do not show most of the genetic changes commonly seen in diffuse astrocytomas.

1 reference

12 December 2020

Low frequency of SV40, JC and BK polyomavirus sequences in human medulloblastomas, meningiomas and ependymomas.

1 reference

12 December 2020

Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer

1 reference

12 December 2020

Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome

1 reference

12 December 2020

Characterisation of X;17(q12;p13) translocation breakpoints in a female patient with hypomelanosis of Ito and choroid plexus papilloma.

1 reference

12 December 2020

The PEN5 epitope identifies an oligodendrocyte precursor cell population and pilocytic astrocytomas

1 reference

12 December 2020

Epidermal growth factor receptor expression and gene amplification in high-grade non-brainstem gliomas of childhood

1 reference

12 December 2020

Extensive genomic abnormalities in childhood medulloblastoma by comparative genomic hybridization.

1 reference

12 December 2020

Cerebellar gliomas in children with NF1: pathology and surgery.

1 reference

12 December 2020

Isolation and characterization of human patched 2 (PTCH2), a putative tumour suppressor gene inbasal cell carcinoma and medulloblastoma on chromosome 1p32.

1 reference

12 December 2020

Absence of p53 gene mutations in a tumor panel representative of pilocytic astrocytoma diversity using a p53 functional assay.

1 reference

12 December 2020

Spectrum of hSNF5/INI1 somatic mutations in human cancer and genotype-phenotype correlations

1 reference

12 December 2020

Somatic mutations in the human homologue of Drosophila patched in primitive neuroectodermal tumours

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12 December 2020

Central nervous system atypical teratoid/rhabdoid tumors of infancy and childhood

1 reference

12 December 2020

The clinical significance of extracellular matrix in gangliogliomas.

1 reference

12 December 2020

Aggressive medulloblastoma with high-level N-myc amplification.

1 reference

12 December 2020

Analysis of oncogene and tumor suppressor gene alterations in pediatric malignant astrocytomas reveals reduced survival for patients with PTEN mutations.

1 reference

12 December 2020

Mutations in the human homologue of the Drosophila segment polarity gene patched (PTCH) in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system.

1 reference

12 December 2020

Cytogenetic abnormalities in human ependymomas.

1 reference

12 December 2020

Enhanced MYCN expression and isochromosome 17q in pineoblastoma cell lines

1 reference

12 December 2020

Molecular cytogenetic analysis of medulloblastomas and supratentorial primitive neuroectodermal tumors by using conventional banding, comparative genomic hybridization, and spectral karyotyping.

1 reference

12 December 2020

Familial occurrence of tumours of the choroid plexus

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12 December 2020

Choroid plexus papilloma and cysts in the Aicardi syndrome: case reports.

1 reference

12 December 2020

More about: cell and molecular biology of simian virus 40: implications for human infections and disease

1 reference

12 December 2020

Deletions of AXIN1, a component of the WNT/wingless pathway, in sporadic medulloblastomas

1 reference

12 December 2020

Malignant transformation of a gangliocytoma/ganglioglioma into a glioblastoma multiforme: a molecular genetic analysis. Case report.

1 reference

12 December 2020

Comparative genomic hybridization in patients with supratentorial and infratentorial primitive neuroectodermal tumors

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12 December 2020

Evidence for a 17p tumor related locus distinct from p53 in pediatric primitive neuroectodermal tumors.

1 reference

12 December 2020

Monosomy 22 in rhabdoid or atypical tumors of the brain.

1 reference

12 December 2020

SV40 and human brain tumors

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12 December 2020

Atypical teratoid/rhabdoid tumors and choroid plexus tumors: when genetics "surprise" pathology.

1 reference

12 December 2020

Constitutional mutations of the hSNF5/INI1 gene predispose to a variety of cancers

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12 December 2020

The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog

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12 December 2020

Molecular analysis of the lissencephaly gene 1 (LIS-1) in medulloblastomas.

1 reference

12 December 2020

DNA sequences similar to those of simian virus 40 in ependymomas and choroid plexus tumors of childhood

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12 December 2020

"Turcot's syndrome": phenotype of brain tumors, survival and mode of inheritance.

1 reference

12 December 2020

Human homolog of patched, a candidate gene for the basal cell nevus syndrome

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12 December 2020

Molecular genetics of pediatric brain stem gliomas. Application of PCR techniques to small and archival brain tumor specimens

1 reference

12 December 2020

Mutational and expression analysis of the NF1 gene argues against a role as tumor suppressor in sporadic pilocytic astrocytomas.

1 reference

12 December 2020

Genetic alterations in pediatric high-grade astrocytomas.

1 reference

12 December 2020

Involvement of multiple chromosome 17p loci in medulloblastoma tumorigenesis

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12 December 2020

Up-regulation of specific NF 1 gene transcripts in sporadic pilocytic astrocytomas.

1 reference

12 December 2020

Germ-line and somatic mutations of the APC gene in patients with Turcot syndrome and analysis of APC mutations in brain tumors.

1 reference

12 December 2020

Genomic imbalances in pediatric intracranial ependymomas define clinically relevant groups

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12 December 2020

p53-dependent apoptosis suppresses tumor growth and progression in vivo

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12 December 2020

Narrowing the critical region for a rhabdoid tumor locus in 22q11

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12 December 2020

Chromosomal abnormalities subdivide ependymal tumors into clinically relevant groups

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12 December 2020

Identification in human brain tumors of DNA sequences specific for SV40 large T antigen.

1 reference

12 December 2020

Molecular analysis of a partial deletion of 22q in a central nervous system rhabdoid tumor

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12 December 2020

Induction of brain tumors by a newly isolated JC virus (Tokyo-1 strain).

1 reference

12 December 2020

Microphthalmia and chorioretinal lesions in a girl with an Xp22.2-pter deletion and partial 3p trisomy: clinical observations relevant to Aicardi syndrome gene localization

1 reference

12 December 2020

p53 mutations in nonastrocytic human brain tumors

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12 December 2020

APC mutations in sporadic medulloblastomas

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12 December 2020

Imbalances of chromosome 17 in medulloblastomas determined by comparative genomic hybridisation and fluorescence in situ hybridisation

1 reference

12 December 2020

Monosomy 22 in rhabdoid or atypical teratoid tumors of the brain

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12 December 2020

Incidence of p14ARF gene deletion in high-grade adult and pediatric astrocytomas.

1 reference

12 December 2020

Central nervous system atypical teratoid/rhabdoid tumors of infancy and childhood: definition of an entity

1 reference

12 December 2020

Isochromosome 17q in primitive neuroectodermal tumors of the central nervous system.

1 reference

12 December 2020

Medulloblastoma growth inhibition by hedgehog pathway blockade

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12 December 2020

Simian virus 40, poliovaccines and human tumors: a review of recent developments

1 reference

12 December 2020

C-MYC expression in medulloblastoma and its prognostic value.

1 reference

12 December 2020

p53 gene mutation and mdm2 gene amplification are uncommon in medulloblastoma.

1 reference

12 December 2020

Absence of allelic loss in cytomegalic neurons of cortical tuber in the Eker rat model of tuberous sclerosis

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12 December 2020

Determination of p53 mutations, EGFR overexpression, and loss of p16 expression in pediatric glioblastomas.

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12 December 2020

Molecular analysis of childhood primitive neuroectodermal tumors defines markers associated with poor outcome

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12 December 2020

High frequency of TP53 mutations in juvenile pilocytic astrocytomas indicates role of TP53 in the development of these tumors.

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12 December 2020

Chromosomal alterations in a case of ganglioglioma.

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12 December 2020

Cytogenetics and Molecular Genetics of Malignant Gliomas and Medulloblastoma

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12 December 2020

Intracranial and spinal metastases from a ganglioglioma with unusual cytogenetic abnormalities in a patient with complex partial seizures.

1 reference

12 December 2020

Oncogene amplification in medulloblastoma: analysis of a case by comparative genomic hybridization and fluorescence in situ hybridization.

1 reference

12 December 2020

Sporadic medulloblastomas contain PTCH mutations.

1 reference

12 December 2020

Mapping of chromosomal gains and losses in primitive neuroectodermal tumors by comparative genomic hybridization

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12 December 2020

Evaluation of proliferative index and cell cycle protein expression in choroid plexus tumors in children.

1 reference

12 December 2020

Microsatellite analysis of childhood brain tumors

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12 December 2020

Comparative genomic hybridization of medulloblastomas and clinical relevance: eleven new cases and a review of the literature

1 reference

12 December 2020

Molecular genetic analysis of ependymal tumors. NF2 mutations and chromosome 22q loss occur preferentially in intramedullary spinal ependymomas

1 reference

12 December 2020

Activating Smoothened mutations in sporadic basal-cell carcinoma

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12 December 2020

The molecular basis of Turcot's syndrome

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12 December 2020

Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer

1 reference

12 December 2020

Indications for a tumor suppressor gene at 22q11 involved in the pathogenesis of ependymal tumors and distinct from hSNF5/INI1.

1 reference

12 December 2020

Analysis of pilocytic astrocytoma by comparative genomic hybridization.

1 reference

12 December 2020

Perinatal induction of medulloblastomas in Syrian golden hamsters by a human polyoma virus (JC)

1 reference

12 December 2020

Induction versus progression of brain tumor development: differential functions for the pRB- and p53-targeting domains of simian virus 40 T antigen

1 reference

12 December 2020

MYCC and MYCN oncogene amplification in medulloblastoma. A fluorescence in situ hybridization study on paraffin sections from the Children's Oncology Group

1 reference

12 December 2020

Analysis of loss of heterozygosity on chromosomes 10q, 11, and 16 in medulloblastomas.

1 reference

12 December 2020

Correlation of loss of heterozygosity at chromosome 9q with histological subtype in medulloblastomas

1 reference

12 December 2020

Chromosomal characteristics of childhood brain tumors

1 reference

12 December 2020

Interstitial deletion of chromosome 11q in a pineoblastoma

1 reference

12 December 2020

Missense mutations in SMOH in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system

1 reference

12 December 2020

Malignant transformation in a ganglioglioma with anaplastic neuronal and astrocytic components. Report of a case with flow cytometric and cytogenetic analysis.

1 reference

12 December 2020

Biologic risk stratification of medulloblastoma: the real time is now.

1 reference

12 December 2020

Astrocytomas and choroid plexus tumors in two families with identical p53 germline mutations.

1 reference

12 December 2020

A new pineoblastoma cell line, PER-480, with der(10)t(10;17), der(16)t(1;16), and enhanced MYC expression in the absence of gene amplification

1 reference

12 December 2020

Mutations of the PATCHED gene in several types of sporadic extracutaneous tumors

1 reference

12 December 2020

Pediatric high-grade astrocytomas show chromosomal imbalances distinct from adult cases

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12 December 2020

Molecular cytogenetic studies of pediatric ependymomas

1 reference

12 December 2020

Deletion of chromosome arm 17p DNA sequences in pediatric high-grade and juvenile pilocytic astrocytomas.

1 reference

12 December 2020

Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome

1 reference

12 December 2020

Comparative genomic hybridization detects an increased number of chromosomal alterations in large cell/anaplastic medulloblastomas.

1 reference

12 December 2020

A novel splice site associated polymorphism in the tuberous sclerosis 2 (TSC2) gene may predispose to the development of sporadic gangliogliomas.

1 reference

12 December 2020

c-MYC interacts with INI1/hSNF5 and requires the SWI/SNF complex for transactivation function

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12 December 2020

Familial posterior fossa brain tumors of infancy secondary to germline mutation of the hSNF5 gene

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12 December 2020

Microsatellite instability occurs in distinct subtypes of pediatric but not adult central nervous system tumors

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12 December 2020

Nuclear localization and mutation of beta-catenin in medulloblastomas

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12 December 2020

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

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12 December 2020

Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog

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12 December 2020

Hedgehog and patched in neural development and disease

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12 December 2020

Regulation of cerebral cortical size by control of cell cycle exit in neural precursors

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12 December 2020

Age and TP53 mutation frequency in childhood malignant gliomas: results in a multi-institutional cohort.

1 reference

12 December 2020

Duplication of 9P and hyperplasia of the choroid plexus: a pathologic, radiologic, and molecular cytogenetics study

1 reference

12 December 2020

Expression of oligodendrocyte progenitor cell antigens by gliomas: implications for the histogenesis of brain tumors

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12 December 2020

Hypomelanosis of Ito in a girl with plexus papilloma and translocation (X;17).

1 reference

12 December 2020

Preferential inactivation of the p53 tumor suppressor pathway and lack of EGFR amplification distinguish de novo high grade pediatric astrocytomas from de novo adult astrocytomas

1 reference

12 December 2020

Medulloblastomas of the desmoplastic variant carry mutations of the human homologue of Drosophila patched.

1 reference

12 December 2020

PTEN mutations in gliomas and glioneuronal tumors.

1 reference

12 December 2020

Haploinsufficiency of Snf5 (integrase interactor 1) predisposes to malignant rhabdoid tumors in mice

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12 December 2020

Developmental pathways: Sonic hedgehog-Patched-GLI

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12 December 2020

Prediction of central nervous system embryonal tumour outcome based on gene expression

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12 December 2020

Mutational analysis of TSC1 and TSC2 genes in gangliogliomas

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12 December 2020

Are juvenile pilocytic astrocytomas benign tumors? A cytogenetic study in 24 cases.

1 reference

12 December 2020

Hedgehog and its patched-smoothened receptor complex: a novel signalling mechanism at the cell surface

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12 December 2020

Evidence for clonal origin of neoplastic neuronal and glial cells in gangliogliomas

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12 December 2020

Comparative genomic hybridization detects many recurrent imbalances in central nervous system primitive neuroectodermal tumours in children

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12 December 2020

Ganglioglioma in a patient with Turcot syndrome. Case report

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12 December 2020

N-myc and c-myc oncogenes amplification in medulloblastomas. Evidence of particularly aggressive behavior of a tumor with c-myc amplification.

1 reference

12 December 2020

The molecular biology of ependymomas

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12 December 2020

Medulloblastomas and primitive neuroectodermal tumors rarely contain polyomavirus DNA sequences

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12 December 2020

When the SWI/SNF complex remodels...the cell cycle

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12 December 2020

Natural simian virus 40 strains are present in human choroid plexus and ependymoma tumors.

1 reference

12 December 2020

Epigenetic silencing of the HIC-1 gene in human medulloblastomas

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12 December 2020

Aicardi syndrome accompanied by auditory disturbance and multiple brain tumors

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12 December 2020

Sporadic medulloblastomas contain oncogenic beta-catenin mutations.

1 reference

12 December 2020

Detection of oncogene amplifications in medulloblastomas by comparative genomic hybridization and array-based comparative genomic hybridization

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12 December 2020

Loss of neurofibromatosis 1 (NF1) gene expression in NF1-associated pilocytic astrocytomas.

1 reference

12 December 2020

Expression of the neurotrophin receptor p75NTR in medulloblastomas is correlated with distinct histological and clinical features: evidence for a medulloblastoma subtype derived from the external granule cell layer

1 reference

12 December 2020

Somatic mutations of WNT/wingless signaling pathway components in primitive neuroectodermal tumors

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12 December 2020

Atypical teratoid/rhabdoid tumor of the central nervous system: a highly malignant tumor of infancy and childhood frequently mistaken for medulloblastoma: a Pediatric Oncology Group study

1 reference

12 December 2020

Comparative genomic hybridization in pineal parenchymal tumors

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12 December 2020

Molecular genetic analysis of chromosome arm 17p and chromosome arm 22q DNA sequences in sporadic pediatric ependymomas

1 reference

12 December 2020

Three choroid plexus papillomas in a patient with Aicardi syndrome. A case report

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12 December 2020

Medulloblastomas and the human neurotropic polyomavirus JC virus

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12 December 2020

Rhabdoid tumor of the kidney: a report of two cases with respective tumor markers and a specific chromosomal abnormality, del(11p13).

1 reference

12 December 2020

Mutations in SUFU predispose to medulloblastoma

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12 December 2020

The relationship between TP53 mutations and overexpression of p53 and prognosis in malignant gliomas of childhood.

1 reference

12 December 2020

10.1007/S11060-004-2750-7

Identifiers

DOI

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11 August 2017

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PubMed ID

15674478